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Topikal proparakain suistimaline bağlı gelişen toksik keratopati

Year 2014, Volume: 24 Issue: 3, 109 - 111, 01.01.2014

Abstract

Gözde ağrı, yanma, batma ve yaşarma şikayetleri ile başvuran kırk iki yaşındaki erkek olguda kornea santralinde epitel defekti, stromal ülserasyon ve korneal ödem saptandı. Sanayide kaynak işi yapan ve şikayetlerinin 40 gündür mevcut olduğunu ifade eden olgunun ısrarlı sorgulanması sonucunda proparakainin topikal formunu kullandığı öğrenildi. Özellikle sanayi, inşaat gibi kornea yaralanması oranı yüksek olan meslek gruplarında proparakain suistimali daha sık görülmektedir. Bu nedenle, kornea epitel defekti, epitel iyileşmesinde gecikme, stromal erime, şiddetli ağrı ve görme keskinliğinde azalma görülen özellikle bu meslek gruplarındaki hastalarda propakain suistimali akla getirilmelidir

References

  • Özbek Z, Korneada İlaç Toksisitesi. Akarçay K, Akata F, Akova YA, ve ark. Türk Oftalmoloji Derneği Eğitim Yayınları No:11 Kornea (1. Baskı). 2009: 577-86.
  • Harnisch JP, Hoffmann F, Dumitrescu L. Side-effects of local anesthetics on the corneal epithelium of the rabbit eye. Albert Von Greafes Arch Klin Exp Ophtalmol. 1975;197: 71-81.
  • Risco JM, Millar LC. Ultrastructural alterations in the endotheli- um in a patient with topical anesthetic abuse keratopaty. Ophtal- mology 1992;99:628-33.
  • Ansari H, Garibaldi DC, Jun AS. Anaesthetic abuse keratopathy as a manifestation of ocular Munchausen’s syndrome. Clin Experi- ment Ophtalmol 2006;34:81-3.
  • Kubaloğlu A, Sarı ES, Evcili PS, ve ark. Topikal proparakain’in neden olduğu sekonder toksik keratopatiler. Türk Oftal Derg 2012;42:30-4.

Topical proparacaine abuse associated with toxic keratopathy

Year 2014, Volume: 24 Issue: 3, 109 - 111, 01.01.2014

Abstract

Forty-two-year-old male presented to hospital for 40 days of pain , foreign body sensation, and tearing on his both eyes. On slit lamp examination, patient had central corneal epithelial defect, stromal ulceration and corneal edema. Detailed history of the case revealed that he was a worker in metal factory and abusing topical proparacaine for forty days for the relief of his symptoms. Proparacaine abuse frequently seen among industry and construction workers because of high prevalance of corneal injury in this population. Because of that, proparacaine abuse must be suspected whenever corneal epithelial defect , delayed epithelial healing, disproportional pain according to stromal wound and visual acuity loss are detected

References

  • Özbek Z, Korneada İlaç Toksisitesi. Akarçay K, Akata F, Akova YA, ve ark. Türk Oftalmoloji Derneği Eğitim Yayınları No:11 Kornea (1. Baskı). 2009: 577-86.
  • Harnisch JP, Hoffmann F, Dumitrescu L. Side-effects of local anesthetics on the corneal epithelium of the rabbit eye. Albert Von Greafes Arch Klin Exp Ophtalmol. 1975;197: 71-81.
  • Risco JM, Millar LC. Ultrastructural alterations in the endotheli- um in a patient with topical anesthetic abuse keratopaty. Ophtal- mology 1992;99:628-33.
  • Ansari H, Garibaldi DC, Jun AS. Anaesthetic abuse keratopathy as a manifestation of ocular Munchausen’s syndrome. Clin Experi- ment Ophtalmol 2006;34:81-3.
  • Kubaloğlu A, Sarı ES, Evcili PS, ve ark. Topikal proparakain’in neden olduğu sekonder toksik keratopatiler. Türk Oftal Derg 2012;42:30-4.
There are 5 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Kamil Yavuzer This is me

Şaban Gönül This is me

Bengü Ekinci Köktekir This is me

Şansal Gedik This is me

Banu Bozkurt This is me

Publication Date January 1, 2014
Published in Issue Year 2014 Volume: 24 Issue: 3

Cite

Vancouver Yavuzer K, Gönül Ş, Köktekir BE, Gedik Ş, Bozkurt B. Topikal proparakain suistimaline bağlı gelişen toksik keratopati. Genel Tıp Derg. 2014;24(3):109-11.

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