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Hiperkalseminin eşlik ettiği cilt altı yağ nekrozu

Year 2014, Volume: 24 Issue: 2, 72 - 74, 01.01.2014

Abstract

Cilt altı yağ nekrozu nadir görülen; gövdede, kollarda, bacaklarda ve yanaklarda ağrılı, eritematöz plak ya da nodüller şeklinde ortaya çıkan yağ dokusunun inflamatuvar iyi huylu hastalığıdır. Cilt altı yağ nekrozu olan yenidoğanlarda sıklıkla asfiktik doğum, mekon- yum aspirasyonu, hipoksi, hipotermi, lokal travma öyküsü mevcuttur. Kendi kendini sınırlayan bir hastalık olmakla beraber ağır hiperkalsemi, hiperlipidemi, geçici trombositopeni gibi komplikasyonlara yol açabilir. Özellikle yaygın cilt tutulumu olan hastalarda hiperkalsemi hayatı tehdit eden bir komplikasyondur. Hiperkalsemiye maruziyet süresi uzarsa metastatik kalsifikasyonlar, nefrokal- sinosis ve böbrek yetmezliği, kalp problemleri ortaya çıkabilir. Bu yazıda bebeklik döneminde hiperkalsemin eşlik ettiği cilt altı yağ nekrozu vakası sunulmuştur

References

  • Karochristou K, Siahanidou T, Kakorou-Tsivitanidou T, Stefanaki K,Mandyla H. Subcutaneous fat necrosis associated with severe hypocalcaemia in a neonate. J Perinatol 2006;26:64-6.
  • Burden AD, Krafchik BR. Subcutaneous fat necrosis of the new- born: A review of 11 cases. Pediatr Dermatol 1999;16:384-7.
  • Tran JT, Sheth AP. Complications of subcutaneous fat necrosis of the newborn: A case report and review of the literature. Pediatr Dermatol 2003;20:257-61.
  • Mitra S, Dove J, Somisetty SK. Subcutaneous fat necrosis in newborn-an unusual case and review of literature. Eur J Pediatr 2011;170:1085-6.
  • Akin MA, Akin L, Coban D, Akcakus M, Balkanli S, Kurtoglu S. Post-operative subcutaneous fat necrosis in a newborn: A case re- port. Fetal Pediatr Pathol 2011;30:363-9.
  • Holzel A. Subcutaneous fat necrosis of the newborn. Arch Dis Child 1951;26:89-91.
  • Fenniche S, Daoud L, Benmously R, et al. Subcutaneous fat necro- sis: report of two cases. Dermatol Online J 2004;10:12.
  • Clay PR. Idiopathic hypercalcaemia with subcutaneous calcium deposits following pseudosclerema. Proc R Soc Med 1956;49:598- 600.
  • Srinath G, Cohen M. Imaging findings in subcutaneous fat necro- sis in a newborn. Pediatr Radiol 2006;36:361-3.
  • Vijayakumar M, Prahlad N, Nammalwar BR, Shanmughasund- haram R. Subcutaneous fat necrosis with hypercalcemia. Indian Pediatr 2006;43:360-3.
  • Hung SH, Tsai WY, Tsao PN, Chou HC, Hsieh WS. J Oral clodro- nate therapy for hypercalcemia related to extensive subcutaneous fat necrosis in a newborn. Formos Med Assoc 2003;102:801-4.
  • Dudink J, Walther FJ, Beekman RP. Subcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcification. Arch Dis Child Fetal Neonatal Ed 2003;88:F343-5.

Subcutaneous fat necrosis with hypercalcemia

Year 2014, Volume: 24 Issue: 2, 72 - 74, 01.01.2014

Abstract

Subcutaneous fat necrosis is a rare and bening inflammatory disease of adipose tissue. It manifests as painful erythematous plaques and nodules in trunk, extremities and cheeks. Neonates with subcutaneous fat necrosis, often had a history of asphyxia ,meconium aspiration, hypoxia, hypothermia and local trauma. Although it is a self-limiting disease, it can lead to complications such as severe hypercalcemia, hyperlipidemia, and transient thrombocytopenia. Especially in patients with extensive skin involvement, hypercalce- mia is a life threatening complication. If exposure to hypercalcemia takes a long time, metastatic calcification, nephrocalcinosis and renal failure, cardiac problems may occur. In this article, a case of subcutaneous fat necrosis accompanied by hypercalcemia in an infant was reported

References

  • Karochristou K, Siahanidou T, Kakorou-Tsivitanidou T, Stefanaki K,Mandyla H. Subcutaneous fat necrosis associated with severe hypocalcaemia in a neonate. J Perinatol 2006;26:64-6.
  • Burden AD, Krafchik BR. Subcutaneous fat necrosis of the new- born: A review of 11 cases. Pediatr Dermatol 1999;16:384-7.
  • Tran JT, Sheth AP. Complications of subcutaneous fat necrosis of the newborn: A case report and review of the literature. Pediatr Dermatol 2003;20:257-61.
  • Mitra S, Dove J, Somisetty SK. Subcutaneous fat necrosis in newborn-an unusual case and review of literature. Eur J Pediatr 2011;170:1085-6.
  • Akin MA, Akin L, Coban D, Akcakus M, Balkanli S, Kurtoglu S. Post-operative subcutaneous fat necrosis in a newborn: A case re- port. Fetal Pediatr Pathol 2011;30:363-9.
  • Holzel A. Subcutaneous fat necrosis of the newborn. Arch Dis Child 1951;26:89-91.
  • Fenniche S, Daoud L, Benmously R, et al. Subcutaneous fat necro- sis: report of two cases. Dermatol Online J 2004;10:12.
  • Clay PR. Idiopathic hypercalcaemia with subcutaneous calcium deposits following pseudosclerema. Proc R Soc Med 1956;49:598- 600.
  • Srinath G, Cohen M. Imaging findings in subcutaneous fat necro- sis in a newborn. Pediatr Radiol 2006;36:361-3.
  • Vijayakumar M, Prahlad N, Nammalwar BR, Shanmughasund- haram R. Subcutaneous fat necrosis with hypercalcemia. Indian Pediatr 2006;43:360-3.
  • Hung SH, Tsai WY, Tsao PN, Chou HC, Hsieh WS. J Oral clodro- nate therapy for hypercalcemia related to extensive subcutaneous fat necrosis in a newborn. Formos Med Assoc 2003;102:801-4.
  • Dudink J, Walther FJ, Beekman RP. Subcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcification. Arch Dis Child Fetal Neonatal Ed 2003;88:F343-5.
There are 12 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Nesibe Akyürek This is me

Mehmet Emre Atabek This is me

Beray Selver Eklioğlu This is me

Sevil Arı Yuca This is me

Publication Date January 1, 2014
Published in Issue Year 2014 Volume: 24 Issue: 2

Cite

Vancouver Akyürek N, Atabek ME, Eklioğlu BS, Yuca SA. Hiperkalseminin eşlik ettiği cilt altı yağ nekrozu. Genel Tıp Derg. 2014;24(2):72-4.