Baş-boyun tümörlerinde reirradyasyondaki güncel gelişmeler

Year 2012, Volume: 22 Issue: 4, 141 - 150, 01.01.2012

Güler Yavaş Çağdaş Yavaş

Abstract

Baş-boyun kanserlerinin tedavisindeki ilerlemelere rağmen %15–50 hastada nüks hastalık gelişmektedir. Tedavi sonrasında takipler- de bu hastalarda ikinci primer hastalık geliştirme riski de yüksektir. Bu risk hayat boyu %14-20’dir. Daha önce radyoterapi uygulan- mış bölgede lokal nüksü gelişen ya da radyoterapi alanı içerisinde ikinci primer tümörü gelişen hastalarda tedavi seçenekleri kısıtlıdır. Sınırlı hacimde tümörü olan hastalarda tercih edilen tedavi şekli kurtarma cerrahisidir. Ancak kurtarma cerrahisi için uygun olmayan ya da cerrahi sonu kötü prognostik faktörleri bulunan hastalarda reirradyasyon alternatif bir tedavi seçeneğidir

Keywords

Baş-boyun tümörleri, reirradyasyon, radyoterapi

Current status of reirradiation for head and neck tumors

Abstract

Despite advances in the treatment of head and neck cancer, 15-50%of patients will develop recurrent disease. Survivors also are at risk to develop second primary tumors. The incidence of developing a second primary tumor is approximately 14-20%during lifeti- me. Therapeutic options are limited for patients who present with locally advanced disease or a second primary disease within the previously irradiated region. Salvage surgery is the preferred option for those with limited-volume disease. However for the patients who are not appropriate for surgery or for those with postoperative poor prognostic factors, reirradiation is an alternative treatment option

Keywords

head and neck tumor, reirradiation, radiotherapy

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