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Spinal kord yaralanmalı hastalarda idrar kültürünün kantitatif çalışması

Year 2012, Volume: 22 Issue: 3, 87 - 91, 01.01.2012

Abstract

Amaç: Kronik dönem spinal kord yaralanmalı SKY hastaların idrar kültürlerinde asemptomatik bakteriüri varlığını tespit etmek ve üreme varlığı ile risk faktörleri arasındaki ilişkiyi araştırmak. Yöntem: SKY’li 36 hasta ve üriner sistem şikayeti olmayan 36 sağlıklı kontrol çalışmaya alındı. Hastaların tümü günde dört kez kendi kendine temiz aralıklı kateterizasyon TAK yapıyordu. Hastalardaki bakteri üreme sıklığı kontrol grubuyla karşılaştırıldı. Hastalarda üreme varlığı üzerine etkili risk faktörleri araştırıldı. Bulgular: SKY’ li hastalarda en sık üreyen bakteri Eshercia coli E. coli idi % 44.4 . Kontrol grubunda en sık üreyen bakteri Koagülaz negatif Stafilokok % 8.4 , ikinci sırada üreyen bakteri E. coli % 2.8 olarak belirlendi. İdrar kültürlerindeki E. coli üreme sıklığı SKY’li hastalarda kontrol grubuna göre istatistik olarak anlamlı derecede yüksekti. Hastalarda asemptomatik bakteriüri varlığı ile cinsiyet, yaralanma süresi, nörolojik seviye, yaralanma tipi ve anal sfikter kusuru arasında anlamlı bir ilişki saptanmadı. Sonuç: Kronik dönemdeki TAK yapan SKY’li hastalarda asemptomatik bakteriüri sık bir bulgudur. SKY’li hastaları takip eden hekimler bu hastalarda asemptomatik bakteriürinin sık bir bulgu olabileceğini göz önünde bulundurmalı ve üriner sistem enfeksiyonun ÜSE klinik bulguları yoksa antimikrobiyal ajanlarla tedavi edilmemelidir

References

  • Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society. Guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40:643-54.
  • Colgan R, Nicolle LE, McGlone A, Hooton TM. Asymptomatic bacteriuria in adults. Am Fam Physician 2006;74:985-90.
  • Nicolle LE. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am 2003;17:367-94
  • Nicolle LE. Asymptomatic bacteriuria in the elderly. Infect Dis Clin North Am 1997;11:647-62.
  • Waites KB, Canupp KC, DeVivo MJ. Epidemiology and risk factors for urinary tract infection following spinal cord injury.Arch Phys Med Rehabil 1993;74:691-5.
  • Waites KB, Canupp KC, DeVivo MJ. Eradication of urinary tract infection following spinal cord injury. Paraplegia 1993;31:645-52.
  • Reşorlu B. Urinary Tract Infections in Spinal Cord Injured Patients. Turk Fiz Tıp Rehab Derg 2009;55:186.
  • Akata F. Özel hasta gruplarında infeksiyon kontrolü: Spinal kord hasarlı hastada infeksiyon kontrolü. Hastane İnfek Derg 2001;5:286-94.
  • Cardenas DD, Mayo ME. Management of bladder dysfunction. In: Braddom RL (ed). Physical Medicine & Rehabilitation. Philadelphia: WB Saunders Company, 2000:561-78.
  • Maynard FM Jr, Bracken MB, Creasey G, Ditunno JF Jr, Donovan WH,Ducker TB, et al. International standarts for neurological and functional classification of spinal cord injury. American Spinal Cord Injury Association. Spinal Cord 1997;35:266-74.
  • Maynard FM, Diokno AC. Urinary infection and complication during clean intermittent catheterization following spinal cord injury. J Urol 1984;132:943-6.
  • De Ruz AE, Leoni E, Cabrera R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 2000;164:1285–9.
  • Hull RA, Rudy DC, Wieser IE, Donovan WH. Virulence factors of E.coli isolates from patients with symptomatic and asymptomatic bacteriuria and neuropathic bladders due to spinal cord and brain injuries. J Clin Microbiol 1998;36:115- 7.
  • Montgomerie JZ. Infections in patients with spinal cord injuries. Clin Infect Dis 1997;25:1285-92.
  • Yaylı G. Asemptomatik Bakteriüriye Yaklaşım. Klin Derg 2000;13:83-5.
  • Kutlu SS. Üriner sistem infeksiyonlarında profilaski. Pamukkale Tıp Derg 2010;3:96-102.
  • Reid G, Nicolle LE. Asymptomatic bacteriuria in spinal cord patients and the elderly. Urol Clin North Am 1999;26:789-95.
  • Lapides J, Diokno AC, Sibler SJ, Lowe BS. Clean intermittent self catheterization in the treatment of urinary tract disease. J Urol 1972;107:458.
  • Hunt HG, Pippa O, Whitaker RH. Intermittent catheterisation: Simple, safe, and effective but underused. Br Med J 1996;312:103-8.
  • Wyndaele JJ. Complications of intermittent catheterization: their prevention and treatment. Spinal Cord 2002;40:536-41.
  • Montgomerie JZ, McCary A, Bennett CJ, Young M, Matias B, Diaz F, et al. Urethral cultures in female patients with a spinal cord injury. Spinal Cord 1997;35:282-5.
  • Sanderson PJ, Weissler S. A comparison of the effect of chlorhexidine antisepsis, soap and antibiotics on bacteriuria, perineal colonization and environmental contamination in spinally injured patients. J Hosp Infect 1990;15:235–43.
  • Barnes DG, Timoney AG, Moulas G, Shaw PJR, Sanderson PJ. Correlation of bacteriological flora of the urethra, glans and perineum with organisms causing urinary tract infection in the spinal injured male patient. Paraplegia 1991;30:851-4.
  • Bakke A, Digranes A. Bacteriuria in patients treated with clean intermittent catheterization. Scand J Infect Dis 1991;23:577-82.
  • Dedeić-Ljubović A, Hukić M. Catheter-related urinary tract infection in patients suffering from spinal cord injuries. Bosn J Basic Med Sci 2009;9:2-9.
  • Bennett CJ, Young MN, Darrington H. Differences in urinary tract infections in male and female spinal cord injury patients on intermittent catheterization. Paraplegia 1995;33:69-72.
  • Donovan WH, Stolov WC, Clowers DE, Clowers MR. Bacteriuria during intermittent catheterization following spinal cord injury. Arch Phys Med Rehabil 1978;59:351–7.
  • Ditunno JF, Formal CS. Chronic spinal cord injury. N Engl J Med 1994;330:550–6.
  • Mohler JL, Cowen DL, Flanigan RC. Suppression and treatment of urinary tract infection in patients with an intermittently catheterized neurogenic bladder. J Urol 1987;138:336–40.
  • Waites KB, Chen Y, DeVivo MJ, Canupp KC, Moser SA. Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury. Arch Phys Med Rehabil 2000;81:764-9.
  • Esclarin De Ruz A, Garcia Leoni E, Herruzo Cabrella R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 2000;164:1285-9.

Quantitative study of urine cultures in patients with spinal cord injuries

Year 2012, Volume: 22 Issue: 3, 87 - 91, 01.01.2012

Abstract

Objective: To investigate the association between risk factors and bacterial reproduction and to determine asymptomatic bacteriurea existence in urinary samples of patients with spinal cord injuries SCI at chronical stage. Methods: Thirty-six patients with SCI and 36 healthy controls with no complaint of urinary system were included into the study. All patients were performed clean intermittent catheterization IC by themselves four times per day. In patients, the frequency of bacterial reproduction was compared with that of health controls. Results: The most commonly encountered bacterium was E. coli % 44.4 in patients. In controls, the most commonly reproducing bacteria were Coagulase negative Staphilococci % 8.4 and E. coli % 2.8 , in turn. In urinary cultures, the frequency of reproduction of E. coli was found to be significantly higher in patients with SCI, compared to healthy controls p0.05 . Conclusion: In patients with SCI performing IC at chronic stage, asymptomatic bacteriurea is a widespread finding. Healtcare providers treating patients with SCI should be aware that asymptomatic bacteriurea may be widespread in such patients, and these patients should not be treated with antimicrobial agents unless clinical findings of urinary tract infections are present

References

  • Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society. Guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40:643-54.
  • Colgan R, Nicolle LE, McGlone A, Hooton TM. Asymptomatic bacteriuria in adults. Am Fam Physician 2006;74:985-90.
  • Nicolle LE. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am 2003;17:367-94
  • Nicolle LE. Asymptomatic bacteriuria in the elderly. Infect Dis Clin North Am 1997;11:647-62.
  • Waites KB, Canupp KC, DeVivo MJ. Epidemiology and risk factors for urinary tract infection following spinal cord injury.Arch Phys Med Rehabil 1993;74:691-5.
  • Waites KB, Canupp KC, DeVivo MJ. Eradication of urinary tract infection following spinal cord injury. Paraplegia 1993;31:645-52.
  • Reşorlu B. Urinary Tract Infections in Spinal Cord Injured Patients. Turk Fiz Tıp Rehab Derg 2009;55:186.
  • Akata F. Özel hasta gruplarında infeksiyon kontrolü: Spinal kord hasarlı hastada infeksiyon kontrolü. Hastane İnfek Derg 2001;5:286-94.
  • Cardenas DD, Mayo ME. Management of bladder dysfunction. In: Braddom RL (ed). Physical Medicine & Rehabilitation. Philadelphia: WB Saunders Company, 2000:561-78.
  • Maynard FM Jr, Bracken MB, Creasey G, Ditunno JF Jr, Donovan WH,Ducker TB, et al. International standarts for neurological and functional classification of spinal cord injury. American Spinal Cord Injury Association. Spinal Cord 1997;35:266-74.
  • Maynard FM, Diokno AC. Urinary infection and complication during clean intermittent catheterization following spinal cord injury. J Urol 1984;132:943-6.
  • De Ruz AE, Leoni E, Cabrera R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 2000;164:1285–9.
  • Hull RA, Rudy DC, Wieser IE, Donovan WH. Virulence factors of E.coli isolates from patients with symptomatic and asymptomatic bacteriuria and neuropathic bladders due to spinal cord and brain injuries. J Clin Microbiol 1998;36:115- 7.
  • Montgomerie JZ. Infections in patients with spinal cord injuries. Clin Infect Dis 1997;25:1285-92.
  • Yaylı G. Asemptomatik Bakteriüriye Yaklaşım. Klin Derg 2000;13:83-5.
  • Kutlu SS. Üriner sistem infeksiyonlarında profilaski. Pamukkale Tıp Derg 2010;3:96-102.
  • Reid G, Nicolle LE. Asymptomatic bacteriuria in spinal cord patients and the elderly. Urol Clin North Am 1999;26:789-95.
  • Lapides J, Diokno AC, Sibler SJ, Lowe BS. Clean intermittent self catheterization in the treatment of urinary tract disease. J Urol 1972;107:458.
  • Hunt HG, Pippa O, Whitaker RH. Intermittent catheterisation: Simple, safe, and effective but underused. Br Med J 1996;312:103-8.
  • Wyndaele JJ. Complications of intermittent catheterization: their prevention and treatment. Spinal Cord 2002;40:536-41.
  • Montgomerie JZ, McCary A, Bennett CJ, Young M, Matias B, Diaz F, et al. Urethral cultures in female patients with a spinal cord injury. Spinal Cord 1997;35:282-5.
  • Sanderson PJ, Weissler S. A comparison of the effect of chlorhexidine antisepsis, soap and antibiotics on bacteriuria, perineal colonization and environmental contamination in spinally injured patients. J Hosp Infect 1990;15:235–43.
  • Barnes DG, Timoney AG, Moulas G, Shaw PJR, Sanderson PJ. Correlation of bacteriological flora of the urethra, glans and perineum with organisms causing urinary tract infection in the spinal injured male patient. Paraplegia 1991;30:851-4.
  • Bakke A, Digranes A. Bacteriuria in patients treated with clean intermittent catheterization. Scand J Infect Dis 1991;23:577-82.
  • Dedeić-Ljubović A, Hukić M. Catheter-related urinary tract infection in patients suffering from spinal cord injuries. Bosn J Basic Med Sci 2009;9:2-9.
  • Bennett CJ, Young MN, Darrington H. Differences in urinary tract infections in male and female spinal cord injury patients on intermittent catheterization. Paraplegia 1995;33:69-72.
  • Donovan WH, Stolov WC, Clowers DE, Clowers MR. Bacteriuria during intermittent catheterization following spinal cord injury. Arch Phys Med Rehabil 1978;59:351–7.
  • Ditunno JF, Formal CS. Chronic spinal cord injury. N Engl J Med 1994;330:550–6.
  • Mohler JL, Cowen DL, Flanigan RC. Suppression and treatment of urinary tract infection in patients with an intermittently catheterized neurogenic bladder. J Urol 1987;138:336–40.
  • Waites KB, Chen Y, DeVivo MJ, Canupp KC, Moser SA. Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury. Arch Phys Med Rehabil 2000;81:764-9.
  • Esclarin De Ruz A, Garcia Leoni E, Herruzo Cabrella R. Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 2000;164:1285-9.
There are 31 citations in total.

Details

Primary Language Turkish
Journal Section Original Article
Authors

Halim Yılmaz This is me

Muhammet Güzel Kurtoglu This is me

Recep Keşli This is me

Osman Tüfekci This is me

Publication Date January 1, 2012
Published in Issue Year 2012 Volume: 22 Issue: 3

Cite

Vancouver Yılmaz H, Güzel Kurtoglu M, Keşli R, Tüfekci O. Spinal kord yaralanmalı hastalarda idrar kültürünün kantitatif çalışması. Genel Tıp Derg. 2012;22(3):87-91.

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