COVID-19'LU GEBE KADINLARDA PERİFERİK YAYMA BULGULARI VE KLİNİK ÖNEMİ

Year 2025, Volume: 35 Issue: 1, 181 - 188, 28.02.2025

Defne Ay Tuncel , Raziye Narin , Turkan Muhlis , Ayşe Yiğit Sönmez

https://doi.org/10.54005/geneltip.1598358

Abstract

ÖZ
Amaç: Periferik kan yayma analizi hematolojide temel bir tanı aracıdır. COVID-19'lu gebe kadınlarda, bu tanı tekniği daha da önem kazanmaktadır. Çalışmamız COVID-19'lu gebe kadınlarda periferik yayma bulgularını açıklamayı amaçlamaktadır.
Materyal ve Yöntemler: Çalışmamızın katılımcıları COVID-19 tanısı almış 50 gebe kadın ve 50 kontrolden oluşmaktadır. Klinik bulgular ilaçlar, periferik kan yayması ve tam kan sayımı parametreleri incelenen değişkenlerden bazılarıdır. Kategorik ölçümleri karşılaştırmak için Ki-Kare testleri kullanıldı. Sayısal ölçümler için Örnek T-Testi kullanıldı. Gruplar tam kan sayımı parametreleri açısından karşılaştırıldı. Gruplar arasında anlamlı farklılıklar belirlendi.
Bulgular: Ferritin, CRP, prokalsitonin, D-dimer, APTT ve fibrinojen değerleri gruplar arasında anlamlı farklılıklar gösterdi. COVID-19 grubunda lenfosit oranı kontrol grubuna göre daha düşüktür. Bant hücreleri, lenfositler, monositler, nötrofiller, vakuollü monositler ve hipersegmente nötrofillerin oranları gruplar arasında istatistiksel olarak anlamlı farklılıklar göstermektedir. Periferik kan anormallikleri mikrobiyal enfeksiyonlarda, özellikle viral enfeksiyonlarda yaygındır.
Sonuçlar: Bu anormallikler altta yatan patofizyolojik değişikliklere dair içgörüler sağlayabilir. COVID-19 hastalarında trombositlerde ve eritrositlerde herhangi bir anormallik gözlemlenmemiştir. Ancak kontrollerle karşılaştırıldığında atipik monositler ve nötrofil hipersegmentasyonu COVID-19 hastalarında önemli ölçüde yüksektir.

Keywords

COVID-19, Periferik Kan Yayması, Gebe Kadınlar, Tam Kan Sayımı, Lenfosit Oranı.

Project Number

yok

PERIPHERAL BLOOD SMEAR FINDINGS AND CLINICAL SIGNIFICANCE IN PREGNANT WOMEN WITH COVID-19

Abstract

ABSTRACT
Aim: Peripheral blood smear analysis is a cornerstone diagnostic tool in hematology. Pregnant women with COVID-19, this diagnostic technique assumes heightened significance. Our study aims to elucidate the peripheral smear findings in pregnant women with COVID-19.
Material and Methods: Our study's participants comprise 50 pregnant women diagnosed with COVID-19 and 50 controls. Clinical findings medications, peripheral blood smear and complete blood count parameters some of examined variables. The Chi-Square tests were employed to compare categorical measurements. Samples T-Test was used for numerical measurements. The groups were compared in terms of complete blood count parameters. Significant differences were identified between the groups.
Results: The values of ferritin, CRP, procalcitonin, D-dimer, APTT, and fibrinogen exhibited significant differences among the groups. The lymphocyte ratio in the COVID-19 group is lower compared to the control group. The proportions of band cells, lymphocytes, monocytes, neutrophils, vacuolated monocytes, and hypersegmented neutrophils exhibit statistically significant differences between the groups. Peripheral blood abnormalities are prevalent in microbial infections, particularly in viral infections.
Conclusions: These abnormalities can provide insights into the underlying pathophysiological changes. In patients with COVID-19, no abnormalities have been observed in platelets and erythrocytes. However, compared to controls, atypical monocytes and neutrophil hypersegmentation are significantly elevated in COVID-19 patients.

Keywords

: COVID-19, Peripheral Blood Smear, Pregnant Women, Complete Blood Count, Lymphocyte Ratio.

Project Number

yok

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