Yaşlılarda Hiponatremiyle İlişkili Faktörler

Year 2019, Volume: 2 Issue: 3, 90 - 94, 31.12.2019

Suleyman Emre Kocyıgıt Ali Ekrem Aydın

Abstract

Amaç: Hiponatremi yaşlı hastalarda en sık görülen
elektrolit bozukluğudur, kötü prognoz ve mortalite artışı ile ilişkilidir. Bu
çalışmanın amacı, yaşlı erişkinlerde hiponatremi ile ilişkili komorbid
hastalıkları ve ilaçları incelemektir.

Gereç ve Yöntemler: Bu retrospektif, kesitsel bir çalışmada geriatri
kliniğine başvuran 240 yaşlı hasta (yatarak ve ayakta tedavi gören hasta)
değerlendirdi. Tüm katılımcıların demografik özellikleri, komorbiditeleri,
ilaçları ve laboratuvar bulguları değerlendirildi. Hiponatremi, sodyum düzeyi
<135 mmol / L olarak tanımlandı.

Bulgular:
Çalışmada hiponatremi
prevalansı % 22.1 idi  ve ortalama yaş
75.27 ± 7.28 olarak saptandı. 
Hiponatremi grubunda hipertansiyon (HT), diabetes mellitus (DM), konjestif
kalp yetmezliği (KKY), aterosklerotik kalp hastalığı (ASKH) sıklığı daha
yüksekti (p<0.05). Diüretik, antidepresan ve antipsikotik ilaç kullanım
sıklığı hiponatremi grubunda daha fazla olarak tespit edildi (p< 0.05).

Sonuç: Bazı komorbiditeler ile diüretik, antidepresan
ve antipsikotik gibi yaşlılarda sık reçete edilen ilaç gruplarının hiponatremi
ile ilişkili olabileceği gösterilmiştir. Bu açıdan geriatri pratiğinde
hastaları değerlendirmek önemlidir.

Keywords

hiponatremi, yaşlılık, diüretik, komorbidite

The Factors Associated Hyponatremia in Older Adults

Abstract

Aim: Hyponatremia is the most common electrolyte
disturbance in older adults and is associated with poor prognosis and increased
mortality. The aim of this study was to investigate comorbid diseases and drugs
associated with hyponatremia in older adults.

Material and Methods: In this
retrospective and cross-sectional study, 240 elderly patients (inpatients and
outpatients) admitted to the geriatrics clinic were evaluated. Demographic
characteristics, comorbidities, drugs and laboratory findings of all participants
were evaluated. Hyponatremia was defined as sodium level <135 mmol / L.

Results: The prevalence of hyponatremia was 22.1%
and the mean age was 75.27 ± 7.28 years. The frequency of hypertension (HT),
diabetes mellitus (DM), congestive heart failure (CHF), and atherosclerotic
heart disease (ASHD) were higher in the hyponatremia group than normonatremia
group (p <0.05). The incidence of diuretics, anridepressant and
antipsychotic drugs usage was higher in hyponatremia group (p <0.05).

Conclusions: Several
comorbidities and frequently prescribed drug groups in older adults such as
diuretics, antidepressants and antipsychotic medicines may be associated with
hyponatremia. In this respect, it is necessary to evaluate patients in
geriatric practice in terms of comorbidities and drugs.

Keywords

hyponatremia, old age, diuretic, comorbidity

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