Resveratrol Content of Turkish Wines Produced from Grapes of Different Regions (Turkish with English Abstract)

Abstract

Resveratrol (3, 5, 4’ trihidroksistilben) is a type of polyphenol which is named as phytoalexin. Polyphenols can be found in skins, seeds and stalks of grapes. Intake of phenolic compounds, especially flavanols through wine consumption is known to have favorable health effects due to their antioxidant properties. Researches show that wine contains resveratrol which is produced under stress conditions as a defense metabolite in grapes. Wine has high amounts of polyphenolic compounds that are known to have protective properties against coronary heart diseases, cancer and inflammation. In-vitro and in-vivo investigations show that red wine has preventive effects on leukemia, skin, lungs and prostate cancers. Recent findings of in-vivo investigations point out that, resveratrol can be an effective agent during the initial, development and progressive phases of cancer. Although there are many researches on determination of resveratrol content of wines in different countries, investigations on this subject are limited in Turkey. In this study, resveratrol contents of wine samples which are produced from grapes grown in different regions of Turkey were determined by High Performance Liquid Chromatography. The results show that resveratrol concentration of the samples changes with according to the type of grapes and the regions they were grown.

Keywords

• Resveratrol, wine, ecological conditions      　　

Farklı Bölgelerin Üzümlerinden Üretilen Türk Şaraplarında Resveratrol Düzeyleri

Abstract

Resveratrol (3,5,4’ trihidroksistilben), fitoaleksin adı verilen bir polifenol çeşididir. Polifenoller üzümlerin kabuklarında, çekirdeklerinde ve saplarında bulunan maddelerdir. Fenolik bileşikler, özellikle flavanoller şarap alımıyla ilgili bilinen sağlık yararları açısından antioksidan özelliklere sahiptirler. Birçok çalışma, üzümlerde stres koşullarında bir savunma metaboliti olarak sentezlenen resveratrolün şarapta bulunduğunu göstermiştir. Şarap insanlarda kansere, iltihaplanmalara ve koroner kalp hastalıklarına karşı koruyucu özellikleri olduğu bilinen polifenol bileşikleri büyük oranda içermektedir. Hücre ve hayvanlarda yapılan çalışmalar, kırmızı şarabın, lösemi, deri, akciğer ve prostat kanserleri gibi pek çok kanser türünde koruyucu etkisi olduğunu göstermektedir. In-vivo çalışmalardan alınan son bilgiler, resveratrolün kanserin başlangıç, gelişme ve ilerleme safhalarında etkili bir ajan olabileceği hakkında bilgi vermektedir. Farklı ülkelerdeki şarapların içerdiği resveratrol miktarının belirlenmesi ile ilgili birçok araştırma olmasına rağmen, Türkiye’de çok az benzer çalışmalar bulunmaktadır. Bu çalışmada, Türkiye’nin farklı bölgelerinde yetişen üzümlerden üretilen şaraplar önemli şarap üreticilerinden temin edilmiş ve resveratrol miktarları Yüksek Performanslı Sıvı Kromatografisi cihazı kullanılarak belirlenmiştir. Elde edilen sonuçlar resveratrol konsantrasyonunun üzüm çeşidine ve bölgelere göre değişebileceğini göstermiştir.

Keywords

• Resveratrol, şarap, ekolojik koşullar     　　 

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