Proteomics Studies of Lactic Acid Bacteria (Turkish with English Abstract)

Year 2013, Volume: 38 Issue: 1, 55 - 62, 01.02.2013

Fadime Kıran Özlem Osmanağaoğlu

Abstract

Lactic acid bacteria which are dominant in the natural flora of fermented foods and commonly used by consumers, are a very important group for the food technology and health sector. Nowadays, proteomics studies on lactic acid bacteria strains are focused on systematic mapping of strains and determination of protein synthesis induced by especially various environmental situations or stresses. These approaches are complementary to each other and provide new insights for the use of bacteria in food industry, in human health and in struggle against bacterial pathogens. Considering the industrial importance of lactic acid bacteria, the use of proteomics methods is expected to increase as well as genomic studies in the near future, especially in the study of strains which will be used as a starter culture or probiotic.

Keywords

Lactic acid bacteria, proteomic, stress.

Laktik Asit Bakterilerinde Proteomik Çalışmalar

Abstract

Fermente gıdaların doğal florasında baskın halde bulunan ve tüketiciler tarafından sıklıkla kullanılan laktik asit bakterileri gıda teknolojisi ve sağlık sektörü açısından oldukça önemli bir gruptur. Günümüzde laktik asit bakterilerinin dâhil olduğu proteomik çalışmalar, suşların sistematik protein haritalarının çıkarılması ve özellikle sentezleri çeşitli çevresel şartlar veya stresler tarafından uyarılan proteinlerin belirlenmesi üzerine odaklanmaktadır. Bu yaklaşımlar birbirinin tamamlayıcısı olup bakterilerin gıda endüstrisinde, insan sağlığında ve bakteriyel patojenlere karşı mücadelede kullanımları için yeni anlayışlar sağlamaktadır. Laktik asit bakterilerinin endüstriyel önemi düşünüldüğünde, yakın gelecekte özellikle starter kültür ya da probiyotik olarak kullanılacak suşların incelenmesinde, proteomik yöntemlerin kullanımının genomiks çalışmalar kadar artacağı öngörülmektedir.

Keywords

Laktik asit bakterileri, proteomik, stres.

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