N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?

Year 2017, Volume: 7 Issue: 4, 385 - 390, 13.12.2017

Osman Bülent Zülfikar Halil Haldun Emiroğlu

https://doi.org/10.16899/gopctd.358803

Abstract

Amaç: Akut pankreatit etiyolojisinde ilaçlar
nispeten seyrek bir nedendir. Çalışmamızda ilaç kullanımına bağlı akut
pankreatit gelişen ve N-asetilsistein tedavisi sonrası iyileşen 6 hastanın
retrospektif değerlendirmesini amaçlanmıştır.

Gereç ve Yöntem: 2007-2017
yılları arasında ilaca bağlı akut pankreatit tanısı alan ve NAC tedavisi
uygulanan 6 çocuk hastanın dosyaları retrospektif olarak incelendi. Altı
hastanın akut pankreatit tanısı "Uluslararası Çocuk Pankreatit Çalışma
Grubu" tarafından önerilen kriterlere göre konuldu. Hastalığın şiddet
derecesi NASPGHAN kriterlerine göre belirlendi.  

Bulgular: Akut pankreatit tedavisi sırasında
NAC uygulanan ilaca bağlı akut pankreatitli 6 hastanın tümü tamamen iyileşti.

Sonuç: NAC, ilaca bağlı akut pankreatit
tedavisi için faydalı görünmektedir.

Keywords

Pankreatit, N-asetil sistein

N-acetyl cysteine: Is it an option for treatment of drug induced acute pancreatitis?

Abstract

Abstract

Aim: Drugs are a
relatively rare cause of acute pancreatitis. We aimed a retrospective
evaluation of 6 patients with drug induced acute pancreatitis, who were
recovered after N-acetyl cysteine treatment.

Materials
and Methods: .  The information in the
files of 6 patients with drug induced acute pancreatitis who were improved
after NAC treatment  between 2007 and
2017 was retrospectively reviewed. The criteria recommended by the
International Study Group of Pediatric Pancreatitis were used for the diagnosis
of acute pancreatitis in 6 patients. The severity of the disease was determined
according to NASPGHAN criteria

Results: All of the 6
patients with drug induced acute pancreatitis who underwent NAC during the
treatment of acute pancreatitis were completely healed.

Conclusion: NAC treatment
seems to be beneficial for drug induced acute pancreatitis.

Keywords

Panceatitis, N-acetyl cysteine

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