Medyan ve Aralık Olarak Raporlanan Çalışmaların Meta-analizi: Erken Evre Meme Kanserinde Cerrahi Yöntem Tercihinde Yaş Faktörünün İncelenmesi

Year 2018, , 175 - 184, 31.07.2018

Esin Avcı

https://doi.org/10.17714/gumusfenbil.331912

Abstract

Sürekli verilere
ait çalışmaların birleştirilmesinde meta-analiz uygulanabilmesi için ortalama
ve standart sapmaya gerek olmaktadır. Bu çalışmada, yayımlanan çalışmaların
medyan, aralık ve örneklem hacmi olarak verilmesi durumunda ortalama ve
standart sapmanın tahmin edilmesi için geliştirilen dönüşüm yöntemleri ele
alınmıştır. Uygulama olarak erken evre meme kanserli hastalara en çok uygulanan
iki tedavi yönteminin tercihinde yaş faktörünün etkisi incelenmiştir. Ele
alınan dönüşüm yöntemleri kullanılarak meta-analizine dahil edilen çalışma
sayısı 9'dan 17'ye çıkarılmış ve örneklem hacmi arttırılarak daha etkin
meta-analizi elde edilmiştir. Analiz sonucunda, yaş faktörünün tedavi yöntemi
tercihinde önemli olmadığı sonucuna varılmıştır.

Keywords

Aralık, Erken evre meme kanseri, Meta-analizi, Örneklem ortalaması, Standart sapma

Meta-analysis of Median and Range Reported Studies: Examination of Age Factor in the preference of Surgical Method in Early Stage Breast Cancer

Abstract

To perform meta-analysis of continuous data,
meta-analyses need the mean and the standart deviation. In this paper, the
conversion methods that improved to estimate the mean and the standart
deviation from published studies that report median, range and sample size were
discussed. The impact of age on preferring the most used surgery type for early
stage breast cancer patients was analyzed. Using the conversion methods, the
number of studies included in the meta-analysis was increased from 9 to 17 and
the sample volume was increased to obtain more efficient meta-analysis. As a
result of the analysis, it was concluded that the age factor was not
significant in the choice of treatment.

Keywords

, Range, Early Stage Breast Cancer, Meta-analysis, Sample mean, Standart deviation

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