Antimicrobial Potential of Usnea longissima Ach. Lichen Against Human Pathogens

Year 2019, Volume: 9 Issue: 4, 710 - 715, 15.10.2019

Kadir Kınalıoğlu Sinem Aydın Bahar Bilgin Sökmen

https://doi.org/10.17714/gumusfenbil.528595

Cited By: 1

Abstract

Lichens are a symbiotic association between a fungus and algae
and/or cyanobacteria. Lichen use as food and dye source, air pollution
indicator, medicinal and decoration.  In
this study, antimicrobial activity of ethyl acetate and ethanol extracts of
Usnea longissima Ach. lichen was searched by disc diffusion method. While
inhibition zones ranges from 14.5 mm to 24.5 mm for bacteria, inhibition zones
ranges from 10 mm to 32 mm for fungi. Lichen extracts exhibited higher activity
than gentamicin
and tetracycline but they showed similar activity to nystatin. The MIC values of the
extract varied between 0.002-0.117 mg/mL against bacteria; while The MIC values
of the extract varied between 0.004-0.059 mg/mL against fungi. According to the obtained
results, it could be said that U. longissima might be an alternative to
synthetic antimicrobial agents.

Keywords

Antimicrobial activity, Lichen, Microorganism

Usnea longissima Ach. Likeninin İnsan Patojenlerine Karşı Antimikrobiyal Potansiyeli

Abstract

Likenler bir mantar ve bir alg ve/ya da siyanobakteri arasındaki simbiyotik
birlikteliklerdir. Likenler besin ve boya kaynağı, hava kirliliği indikatörü,
tıbbi ve dekorasyon amaçlı kullanılmaktadır. Bu çalışmada, Usnea longissima
Ach. likeninin etanol ve etil asetat ekstraktlarının antimikrobiyal
aktiviteleri disk difüzyon metodu ile araştırıldı. Bakteriler için inhibisyon
zonları 14.5 mm ve 24.5 mm arasında değişirken; mantarlar için 10 mm ve 32 mm
arasında değişmektedir. Liken ekstraktları gentamisin ve tetrasiklinden daha
yüksek ve nistatine benzer aktivite göstermiştir. Ekstraktların bakterilere
karşı MİK değerleri 2-117 µg/mL arasında değişirken; mantarlara karşı MİK
değerleri 4-59 µg/mL arasında değişmektedir. Elde edilen sonuçlara göre, U.
longissima’nın sentetik antimikrobiyal ajanlara alternatif olabileceği
söylenebilir.

 

Keywords

Antimikrobiyal aktivite, Liken, Mikroorganizma

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