Retrospective Study on Serum Electrolytes in Women with Postmenoposal Osteoporosis

Yıl 2022, , 1221 - 1226, 27.09.2022

Büşra Şahin , Gülsemin Ertürk Çelik , Sezin Ertürk Aksakal , Yaprak Ustun

https://doi.org/10.37989/gumussagbil.1137155

Öz

The aim of this study is to analyse the effect of serum sodium-potassium ratio on osteoporosis and to perform correlation analysis associated with Bone Mineral Density. One hundred one patients applying to Etlik Zubeyde Hanım Women's Health Teaching and Research Hospital between June 2021 and February 2022 were included to our retrospective study. Demographic data, serum electrolyte lipid profile, C-Reactive Protein (CRP), 25-hydroxy vitamin D, blood urea nitrogen (BUN) and creatinin values of the patients were recorded into patient follow-up forms. Median age and menapouse duration of patient with osteoporosis were significantly higher than control group. Significant difference was not detected in lipid profile, electrolyte values, BUN/creatinin, HDL/LDL, sodium/potassium ratio of the patients. Significant negative correlation was detected between T-score, BUN/Cr ratio and menapouse duration according to the correlation analysis which was implemented. In order to reduce osteoporosis associated fractures and for early treatment, detecting the modifiable factors is key in patients with osteoporosis. In accordance to our study siginificant relationship between serum electrolytes and osteoporosis was not detected nevertheless, it is needed to have wide ranging studies in patients with osteoporosis for this particular subject.

Anahtar Kelimeler

Bone mineral density, Osteoporosis, Serum electrolyte

Postmenopozal Osteoporozlu Kadınlarda Serum Elektrolitleri Üzerine Retrospektif Çalışma

Öz

Bu çalışmanın amacı serum sodyum-potasyum oranının osteoporoz üzerindeki etkisinin araştırılması ve kemik mineral dansitometre (KMD) ile korelasyonunun analiz edilmesidir. Retrospektif gözlemsel çalışmamız için Sağlık Bilimleri Üniversitesi Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim Araştırma Hastanesi’ne Haziran 2021 ve Şubat 2022 tarihleri arasında rutin kontrol için başvuran ve KMD istenen 101 hasta dahil edildi. Hastaların demografik verileri ve serum elektrolitleri lipit profili, C-Reaktif Protein (CRP), 25-hidroksi vitamin D, Kan Üre Azotu (BUN) ve kreatinin (Cr) değerleri hasta takip formuna kaydedildi. Osteoporoz olan hastalarda ortanca yaş ve menopoz süresi kontrol grubuna göre istatiksel olarak anlamlı yüksek bulundu. Hastaların lipid profili, elektrolit değerleri, BUN, kreatinin, BUN/kreatinin, HDL/LDL, sodyum/potasyum oranları arasında anlamlı bir fark saptanmadı. Yapılan korelasyon analizinde T-skoru ile BUN/Cr oranı ve menopoz süresi arasında negatif yönde anlamlı bir ilişki bulundu. Osteoporozlu hastalarda değiştirilebilir risk faktörlerinin saptanması osteoporoza bağlı kırıkların azaltılması ve erken tedavisi için önem arzetmektedir. Biz çalışmamızda serum elektrolitleri ve osteoporoz arasında anlamlı bir ilişki saptamadık ancak osteoporozlu hastalarda bu konuda daha geniş ölçekli çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

Kemik mineral yoğunluğu, Osteoporoz, Serum elektrolitleri

Kaynakça

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