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Yara Yönetiminde Yenilikçi Yaklaşımlar

Year 2019, Volume: 8 Issue: 4, 481 - 494, 31.12.2019

Abstract

Yara herhangi bir fiziksel hasar
sonucunda doku bütünlüğünün bozulmasıdır. Toplumda diyabet, periferik damar
hastalıkları gibi kronik hastalıkların artmasıyla birlikte deri bütünlüğünü
bozan akut ya da kronik yaraların görülme sıklığı da yükselmiştir. Bu durum
yeni yara tedavi yöntemleri ve seçeneklerini çoğaltmıştır. Yara tedavisinde son
yıllarda gazlı bezin yerine geçen modern yara örtüleri tedavi seyrini olumlu
yönde değiştirmiştir. Yara tedavisinde yapışmayan, nemi koruyan, kokuyu önleyen
ve toksik olmayan yara örtüleri idealdir. Son yıllarda gelişen tıp ve
teknolojiye paralel olarak yara tedavisinde de çeşitlilik artmıştır. Negatif
basınçlı yara tedavisi, hiperbarik oksijen tedavisi, elektrik stimülasyonu ve ultrason
gibi uygulamalar sık olarak kullanılmaktadır. Uzmanlık gerektiren bu uygulamalar
ile kronik yara tedavisinde olumlu sonuçlar elde edilmiştir. Yara iyileşmesi
sistemik ve lokal faktörlerden etkilenmektedir. Bu nedenle etkili yara tedavisi
için hasta tüm yönleriyle değerlendirilmeli ve tedavinin planlanması da bireye
özgü yapılmalıdır. İdeal tedavi yöntemi için hücre yenilenmesine olanak
sağlayan, hastaya ağrı ve zarar vermeyen ve en kısa sürede iyileşmeyi sağlayan
uygulamalar seçilmelidir. 

References

  • 1. Drosou, A., Falabella, A., Kirsner, R.S. (2003). Antisptics on Wounds: An Area of Controversy. Wounds, 15 (5), 149- 166.2. Güneş, Y.Ü., Eşer, İ. (2006). Nemli Yara İyileşmesi ve Oklusif Pansumanların Nemli Yara İyileşmesindeki Önemi. C.Ü. Hemşirelik Yüksekokulu Dergisi, 10 (2), 57-65.3. Türsen, Ü. (2013). Ülser Tedavisinde Yara Örtüleri. Turkish Journal of Dermatology, 7, 61-71.4. Kurtoğlu, A.H., Karataş, A. (2009). Yara Tedavisinde Güncel Yaklaşımlar: Modern Yara Örtüleri. Ankara Eczacılık Fakültesi Dergisi, 38 (3), 211-132.5. Mendez-Eastman, S. (2005). Wound Dressing Categories. Plastic Surgery Nursing, 25 (2), 95 99.6. Yazar, H., Karaca, İ.R. (2016). Yumuşak Dokuda Yara İyileşmesi, Etkileyen Faktörler ve Skar Revizyonu. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 15, 152-161.7. Dowsett, C. (2002). The Role of the Nurse in Wound Bed Preparation. Nursing Standard, 16 (44), 69-76.8. Gürsoy, A. (2007). Yara Örtüsü Seçimi. HEAD, 4 (1), 6-9.9. Calianno, C. (2003). How to Choose the Right Treatment and Dressing for the Wound. Nursing Management, 6 (10), 12-14.10. Fonder, E. (2008). Treating the Chronic Wound: A Practical Approach to the Care of Nonhealing Wounds and Wound Care Dressings. Journal of the American Academy of Dermatology, 58 (2), 185-206.11. Kim, J.O., Park, J.K., Kim, J.H., Jin, S.G., Yong, C.S., Li, D.X., et al. (2008). Development of Polyvinyl Alcohol-Sodium Alginate Gel-Matrix Based Wound Dressing System Containing Nitrofurazone. International Journal of Pharmaceutics, 359 (1-2), 79–86. 12. Chin, G.A., Diegelmann, R.F., Schultz, G.S. (2005). Cellula and Molecular Regulation of Wound Healing. Wound Healing. (s.17-39). Boca Raton: Taylor&Francis Group.13. Altay, P., Başal, G. (2010). Yara örtüleri. Tekstil Teknolojileri Elektronik Dergisi, 4 (1), 109-121.14. Yalçın, Atar, N. (2014). Basınç Yaraları. Erişkin Yoğun Bakım Hastalarında Temel Sorunlar ve Hemşirelik Bakımı. (s. 149-164). İstanbul: Nobel Tıp Kitapevi.15. Dumville, J.C, O’Meara, S., Deshpande, S. (2011). Hydrogel dressing for Healing Foot Ulcers. Cochrane Database Systematic Review, 7 (9), CD009101.16. Stashak, T.S, Farstvedt, E., Othic, A. (2004). Update on Wound Dressings: Indications and Best Use. Clinical Techniques in Equine Practice, 3 (2), 148-163.17. Dumville, J.C, Deshpande, S., O’Meara, S., Speak, K. (2012) Hydrocolloid Dressing For Healing Diabetic Foot Ulcers. Cochrane Database Systematic Review, 15 (2), CD009099.18. Pott, F.S, Meier, M.J, Stocco, JG, Crozeta, K, Ribas, JD. (2014). The Effectiveness of Hydrocolloid Dressings Versus other Dressings in the Healing of Pressure Ulcers in Adults and Older Adults: A Systematic Review and Meta-Analysis. Revista Latino-Americana de Enfermagem, 22 (3), 511-520.19. Qaseem, A., Humphrey, L.L., Forciea, M.A., Starkey, M., Danberg, T.D. (2015). Treatment of Pressure Ulcers: A Clinical Practice Guideline from the American College of Physicians. Annals of Internal Medicine, 162 (5), 370-379.20. Qaseem, A., Mir, T.P., Starkey, M., Danberg, T.D. (2015). Risk Assessment and Prevention of Pressure Ulcers: A Clinical Practice Guideline from the American College of Physicians. Annals of Internal Medicine, 162 (5), 359-369.21. Dreifke, M.B., Jayasuriya, A.A., Jayasuriya, A.C. (2015). Current Wound Healing Procedures and Potential Care. Material Science and Engineer C Material for Biological Applicatons, 48, 651–662. 22. Purner, S.K, Babu, M. (2000). Collagen Based Dressings-A Review. Burns, 26 (1), 54–62.23. Brett, D.A. (2008). Review of Collagen and Collagen Based Wound Dressings. Wounds, 20 (12), 347-356.24. Chen, R.N., Wang, G.M., Chen, C.H., Ho, H.O., Sheu, M.T. (2006). Development of Chitosan/Collagen Matrixes as a Wound Dressing. Biomacromolecules, 7 (4), 1058–1064.25. Sezer, A.D., Hatipoğlu, F., Cevher, E., Oğurtan, Z, Baş, A.L., Akbuğa, J. (2007). Chitosan Film Containing Fucoidan as a Wound Dressing for Dermal Burn Healing: Preparation and in Vitro/İn Vivo Evaluation. An Official Journal of the American Association of Pharmaceutical Scientists, 8 (2), 1-8.26. Uppal, R., Ramaswamy, G.N., Arnold, C., Goodband, R., Wang, Y. (2011). Hyaluronic Acid Nanofiber Wound Dressing—Production, Characterization, and in Vivo Behavior. Journal of Biomedical Materials Research, 97 (1), 20-29. 27. Supp, D.M., Boyce, S.T. (2005). Engineered Skin Substitutes: Practices and Potentials. Clinics in Dermatology, 23 (4), 403-12.28. Özkayın, N., Erdem, M., Tiftikçioğlu, Y.Ö. (2017). Negatif Basınçlı Yara Tedavisi ve Ortopedi Pratiğinde Kullanımı. TOTBİD Dergisi, 16, 203–208.29. Aktaş, Ş. (2012). Kronik Yarada Lokal Faktörler ve Yardımcı Tedaviler. ANKEM Dergisi, 26 (2), 217-222.30. Webster, J., Scuffham, P., Stankievicz, M., Chaboyer, W. (2014). Negative Pressure Wound Therapy for Skin Grafts and Surgical Wounds Healing By Primary Intention. Cochrane Systematic Review, 18 (4), CD009261.31. Ubbink, D.T., Westerbos, S.J., Evand, D., Land, L.,Vermeılen, H. (2008). Topical Negative Pressure for Treating Chronic Wounds. Cochrane Database Systematc Review, 16 (3), CD001898.32. Dumville, J.C., Hinchliffe, R.J., Cullum, N., Game, F., Stubbs, N., Sweeting, M., et al. (2013). Negative Pressure Wound Therapy for Treating Foot Wounds in People with Diabetes Mellitus. Cochrane Database Systematc Review, 17 (10), CD010318.33. Hingorani, A., Lamuraglia, G.M., Henke, P., Meissner, M.H., Loretz, L., Zinszer, K.M., et al. (2016). The Management of Diabetic Foot: A Clinical Practice Guideline by the Society for Vascular Surgery in Collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine. Journal of Vascular Surgery, 63 (2), 3-21.34. Aydın, F., Aktaş, Ş., Olgaç, V., Mezdeği, A., Karamülsel, S. (2003). Deneysel Kompartman Sendromunda Cerrahi Dekompresyonla Kombine Edilen Hiperbarik Oksijen Tedavisinin Etkinliği. Ulusal Travma Acil Cerrahi Dergisi, 9 (3), 176–182.35. Sahni, T., Singh, P., John, M.J. (2003). Hyperbaric Oxygen Therapy: Current Trends and Applications. Journal of Association Physicians India, 51, 280–284.36. Mehta, Vandana, De., Abhishek, Balachandran, C. (2009). Hyperbaric Oxygen Therapy. Journal of Pakistan Association of Dermatologists, 19 (3), 164–167.37. Thom, S.R. (2011). Hyperbaric Oxygen: its Mechanisms and Efficiency. Plastic and Reconstrictive Surgery, 127 (1), 131–141.38. Stoekenbroek, R.M., Santema, T.B., Legemate, D.A., Ubbink, D.T., Brink, A., Koelemay, M.J.W. (2014). Hyperbaric Oxygen for the Treatment of Diabetic Foot Ulcers. Department of Surgery, Academic Medical Center. Systematic Review, 47 (6), 647-655.39. Liu, R., Ling, Li., Mengliu, Y., Guenther, B., Ganghi, Y. (2013). Systematic Review of the Effectiveness of Hyperbaric Oxygenation Therapy in the Management of Chronic Diabetic Foot Ulcers. Mayo Clinic Proceeding, 88 (2), 166-175.40. Löndahl, M., Katzman, P., Nillson, A., Hammarlund, C. (2010). Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients with diabetes. Diabetes Care, 33 (5), 998-1003.41. Öztopalan, D.F., Işık, R., Durmuş, A.S. (2017). Yara İyileşmesinde Büyüme Faktörleri ve Sitokinlerin Rolü. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 10 (1), 83-88.42. Bao, P., Kodro, A., Michael, S., Paul, H. (2008). The Role of Vascular Endothelial Growth Factor in Wound Healing. Journal of Surgical Research, 153 (2), 347-358. 43. Lee, A.R.C., Leem, H., Jaegwan, L., Park, K.C. (2005). Reversal of Silver Sulfadiadine-İmpaired Wound Healing by Epidermal Growth Factor. Biomaterials, 26 (10), 4670-4676.44. Greer, N., Foman, N.A., MacDonald, R., Dorrian, J., Fitzgerald, P., Rutks, I., et al. (2013). Advanced Wound Care Therapies for Nonhealing Diabetic, Venous, and Arterial Ulcers. Annals of Internal Medicine, 159, 532-542.45. Ulma, R.M., Aghaloo, T.L., Freymiller, E.G. (2013). Wound Healing. Oral and Maxillofacial Trauma. (S. 9-29). Philadelphia: Saunders.46. Brrigs, M., Nelson, E.A., Martyn, S., James, M. (2012). Topical Agents or Dressings for Pain in Venous Leg Ulcers. Cochrane Database Systematic Review, 14 (11), CD001177.47. Saydam, İ.M, Yılmaz, S., Seven, E. (2005). Topikal Olarak Uygulanan Nitrofurazon ve Rifamisin’in Tam Kalınlıkta Yara İyileşmesi Üzerine Etkileri. C. Ü. Tıp Fakültesi Dergisi, 27 (3), 113-120.48. Lakshmipathy, U., Verfaillie, C. (2005). Stem Cell Plasticity. Blood Reviews, 19 (1), 29-38. 49. Ding, D.C., Shyu, W.C., Lin, S.Z. (2011). Mesenchymal Stem Cells. Cell Transplantation 20 (1), 5-14. 50. Jackson, W.M., Nesti, L.J., Tuan, R.S. (2012). Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells. 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Innovative Approaches in Wound Management

Year 2019, Volume: 8 Issue: 4, 481 - 494, 31.12.2019

Abstract

Wound is the deterioration of
tissue integrity as a result of any physical damage. With the increase of
chronic diseases such as diabetes and peripheral vascular diseases, there is an
increase in the incidence of acute or chronic wounds that disrupt the skin
integrity. This situation has increased the number of new wound treatment
methods and options. In recent years, modern dressings that replaced the gauze
in the treatment of wounds changed the course of treatment positively.
Non-adherent,
moisture-proof, odor-free and non-toxic dressings are ideal for wound
treatment. In parallel with the developing medicine and technology, wound
treatment has increased in recent years. Applications such as negative pressure
wound therapy, hyperbaric oxygen therapy, electrical stimulation and ultrasound
are frequently used.
With these applications that require
expertise, positive results have been obtained in chronic wound treatment.
Wound healing is affected by systemic and local factors. Therefore, patients
should be evaluated for all aspects of wound healing and effective treatment
planning should be made specific to the
individual. Ideal
treatment method allows cell renewal, not pain and do not harm to patient and
provide recovery as soon as possible.

References

  • 1. Drosou, A., Falabella, A., Kirsner, R.S. (2003). Antisptics on Wounds: An Area of Controversy. Wounds, 15 (5), 149- 166.2. Güneş, Y.Ü., Eşer, İ. (2006). Nemli Yara İyileşmesi ve Oklusif Pansumanların Nemli Yara İyileşmesindeki Önemi. C.Ü. Hemşirelik Yüksekokulu Dergisi, 10 (2), 57-65.3. Türsen, Ü. (2013). Ülser Tedavisinde Yara Örtüleri. Turkish Journal of Dermatology, 7, 61-71.4. Kurtoğlu, A.H., Karataş, A. (2009). Yara Tedavisinde Güncel Yaklaşımlar: Modern Yara Örtüleri. Ankara Eczacılık Fakültesi Dergisi, 38 (3), 211-132.5. Mendez-Eastman, S. (2005). Wound Dressing Categories. Plastic Surgery Nursing, 25 (2), 95 99.6. Yazar, H., Karaca, İ.R. (2016). Yumuşak Dokuda Yara İyileşmesi, Etkileyen Faktörler ve Skar Revizyonu. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, 15, 152-161.7. Dowsett, C. (2002). The Role of the Nurse in Wound Bed Preparation. Nursing Standard, 16 (44), 69-76.8. Gürsoy, A. (2007). Yara Örtüsü Seçimi. HEAD, 4 (1), 6-9.9. Calianno, C. (2003). How to Choose the Right Treatment and Dressing for the Wound. Nursing Management, 6 (10), 12-14.10. Fonder, E. (2008). Treating the Chronic Wound: A Practical Approach to the Care of Nonhealing Wounds and Wound Care Dressings. Journal of the American Academy of Dermatology, 58 (2), 185-206.11. Kim, J.O., Park, J.K., Kim, J.H., Jin, S.G., Yong, C.S., Li, D.X., et al. (2008). Development of Polyvinyl Alcohol-Sodium Alginate Gel-Matrix Based Wound Dressing System Containing Nitrofurazone. International Journal of Pharmaceutics, 359 (1-2), 79–86. 12. Chin, G.A., Diegelmann, R.F., Schultz, G.S. (2005). Cellula and Molecular Regulation of Wound Healing. Wound Healing. (s.17-39). Boca Raton: Taylor&Francis Group.13. Altay, P., Başal, G. (2010). Yara örtüleri. Tekstil Teknolojileri Elektronik Dergisi, 4 (1), 109-121.14. Yalçın, Atar, N. (2014). Basınç Yaraları. Erişkin Yoğun Bakım Hastalarında Temel Sorunlar ve Hemşirelik Bakımı. (s. 149-164). İstanbul: Nobel Tıp Kitapevi.15. Dumville, J.C, O’Meara, S., Deshpande, S. (2011). Hydrogel dressing for Healing Foot Ulcers. Cochrane Database Systematic Review, 7 (9), CD009101.16. Stashak, T.S, Farstvedt, E., Othic, A. (2004). Update on Wound Dressings: Indications and Best Use. Clinical Techniques in Equine Practice, 3 (2), 148-163.17. Dumville, J.C, Deshpande, S., O’Meara, S., Speak, K. (2012) Hydrocolloid Dressing For Healing Diabetic Foot Ulcers. Cochrane Database Systematic Review, 15 (2), CD009099.18. Pott, F.S, Meier, M.J, Stocco, JG, Crozeta, K, Ribas, JD. (2014). The Effectiveness of Hydrocolloid Dressings Versus other Dressings in the Healing of Pressure Ulcers in Adults and Older Adults: A Systematic Review and Meta-Analysis. Revista Latino-Americana de Enfermagem, 22 (3), 511-520.19. Qaseem, A., Humphrey, L.L., Forciea, M.A., Starkey, M., Danberg, T.D. (2015). Treatment of Pressure Ulcers: A Clinical Practice Guideline from the American College of Physicians. Annals of Internal Medicine, 162 (5), 370-379.20. Qaseem, A., Mir, T.P., Starkey, M., Danberg, T.D. (2015). Risk Assessment and Prevention of Pressure Ulcers: A Clinical Practice Guideline from the American College of Physicians. Annals of Internal Medicine, 162 (5), 359-369.21. Dreifke, M.B., Jayasuriya, A.A., Jayasuriya, A.C. (2015). Current Wound Healing Procedures and Potential Care. Material Science and Engineer C Material for Biological Applicatons, 48, 651–662. 22. Purner, S.K, Babu, M. (2000). Collagen Based Dressings-A Review. Burns, 26 (1), 54–62.23. Brett, D.A. (2008). Review of Collagen and Collagen Based Wound Dressings. Wounds, 20 (12), 347-356.24. Chen, R.N., Wang, G.M., Chen, C.H., Ho, H.O., Sheu, M.T. (2006). Development of Chitosan/Collagen Matrixes as a Wound Dressing. Biomacromolecules, 7 (4), 1058–1064.25. Sezer, A.D., Hatipoğlu, F., Cevher, E., Oğurtan, Z, Baş, A.L., Akbuğa, J. (2007). Chitosan Film Containing Fucoidan as a Wound Dressing for Dermal Burn Healing: Preparation and in Vitro/İn Vivo Evaluation. An Official Journal of the American Association of Pharmaceutical Scientists, 8 (2), 1-8.26. Uppal, R., Ramaswamy, G.N., Arnold, C., Goodband, R., Wang, Y. (2011). Hyaluronic Acid Nanofiber Wound Dressing—Production, Characterization, and in Vivo Behavior. Journal of Biomedical Materials Research, 97 (1), 20-29. 27. Supp, D.M., Boyce, S.T. (2005). Engineered Skin Substitutes: Practices and Potentials. Clinics in Dermatology, 23 (4), 403-12.28. Özkayın, N., Erdem, M., Tiftikçioğlu, Y.Ö. (2017). Negatif Basınçlı Yara Tedavisi ve Ortopedi Pratiğinde Kullanımı. TOTBİD Dergisi, 16, 203–208.29. Aktaş, Ş. (2012). Kronik Yarada Lokal Faktörler ve Yardımcı Tedaviler. ANKEM Dergisi, 26 (2), 217-222.30. Webster, J., Scuffham, P., Stankievicz, M., Chaboyer, W. (2014). Negative Pressure Wound Therapy for Skin Grafts and Surgical Wounds Healing By Primary Intention. Cochrane Systematic Review, 18 (4), CD009261.31. Ubbink, D.T., Westerbos, S.J., Evand, D., Land, L.,Vermeılen, H. (2008). Topical Negative Pressure for Treating Chronic Wounds. Cochrane Database Systematc Review, 16 (3), CD001898.32. Dumville, J.C., Hinchliffe, R.J., Cullum, N., Game, F., Stubbs, N., Sweeting, M., et al. (2013). Negative Pressure Wound Therapy for Treating Foot Wounds in People with Diabetes Mellitus. Cochrane Database Systematc Review, 17 (10), CD010318.33. Hingorani, A., Lamuraglia, G.M., Henke, P., Meissner, M.H., Loretz, L., Zinszer, K.M., et al. (2016). The Management of Diabetic Foot: A Clinical Practice Guideline by the Society for Vascular Surgery in Collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine. Journal of Vascular Surgery, 63 (2), 3-21.34. Aydın, F., Aktaş, Ş., Olgaç, V., Mezdeği, A., Karamülsel, S. (2003). Deneysel Kompartman Sendromunda Cerrahi Dekompresyonla Kombine Edilen Hiperbarik Oksijen Tedavisinin Etkinliği. Ulusal Travma Acil Cerrahi Dergisi, 9 (3), 176–182.35. Sahni, T., Singh, P., John, M.J. (2003). Hyperbaric Oxygen Therapy: Current Trends and Applications. Journal of Association Physicians India, 51, 280–284.36. Mehta, Vandana, De., Abhishek, Balachandran, C. (2009). Hyperbaric Oxygen Therapy. Journal of Pakistan Association of Dermatologists, 19 (3), 164–167.37. Thom, S.R. (2011). Hyperbaric Oxygen: its Mechanisms and Efficiency. Plastic and Reconstrictive Surgery, 127 (1), 131–141.38. Stoekenbroek, R.M., Santema, T.B., Legemate, D.A., Ubbink, D.T., Brink, A., Koelemay, M.J.W. (2014). Hyperbaric Oxygen for the Treatment of Diabetic Foot Ulcers. Department of Surgery, Academic Medical Center. Systematic Review, 47 (6), 647-655.39. Liu, R., Ling, Li., Mengliu, Y., Guenther, B., Ganghi, Y. (2013). Systematic Review of the Effectiveness of Hyperbaric Oxygenation Therapy in the Management of Chronic Diabetic Foot Ulcers. Mayo Clinic Proceeding, 88 (2), 166-175.40. Löndahl, M., Katzman, P., Nillson, A., Hammarlund, C. (2010). Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients with diabetes. Diabetes Care, 33 (5), 998-1003.41. Öztopalan, D.F., Işık, R., Durmuş, A.S. (2017). Yara İyileşmesinde Büyüme Faktörleri ve Sitokinlerin Rolü. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 10 (1), 83-88.42. Bao, P., Kodro, A., Michael, S., Paul, H. (2008). The Role of Vascular Endothelial Growth Factor in Wound Healing. Journal of Surgical Research, 153 (2), 347-358. 43. Lee, A.R.C., Leem, H., Jaegwan, L., Park, K.C. (2005). Reversal of Silver Sulfadiadine-İmpaired Wound Healing by Epidermal Growth Factor. Biomaterials, 26 (10), 4670-4676.44. Greer, N., Foman, N.A., MacDonald, R., Dorrian, J., Fitzgerald, P., Rutks, I., et al. (2013). 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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Derlemeler
Authors

Senan Mutlu This is me 0000-0002-0409-5209

Emel Yılmaz 0000-0002-5127-6651

Publication Date December 31, 2019
Published in Issue Year 2019 Volume: 8 Issue: 4

Cite

APA Mutlu, S., & Yılmaz, E. (2019). Yara Yönetiminde Yenilikçi Yaklaşımlar. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 8(4), 481-494.
AMA Mutlu S, Yılmaz E. Yara Yönetiminde Yenilikçi Yaklaşımlar. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. December 2019;8(4):481-494.
Chicago Mutlu, Senan, and Emel Yılmaz. “Yara Yönetiminde Yenilikçi Yaklaşımlar”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 8, no. 4 (December 2019): 481-94.
EndNote Mutlu S, Yılmaz E (December 1, 2019) Yara Yönetiminde Yenilikçi Yaklaşımlar. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 8 4 481–494.
IEEE S. Mutlu and E. Yılmaz, “Yara Yönetiminde Yenilikçi Yaklaşımlar”, Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 8, no. 4, pp. 481–494, 2019.
ISNAD Mutlu, Senan - Yılmaz, Emel. “Yara Yönetiminde Yenilikçi Yaklaşımlar”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 8/4 (December 2019), 481-494.
JAMA Mutlu S, Yılmaz E. Yara Yönetiminde Yenilikçi Yaklaşımlar. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2019;8:481–494.
MLA Mutlu, Senan and Emel Yılmaz. “Yara Yönetiminde Yenilikçi Yaklaşımlar”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 8, no. 4, 2019, pp. 481-94.
Vancouver Mutlu S, Yılmaz E. Yara Yönetiminde Yenilikçi Yaklaşımlar. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2019;8(4):481-94.