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Maternal Nutrition and Later Life Obesity

Year 2020, Volume: 9 Issue: 1, 36 - 43, 02.04.2020
https://doi.org/10.37989/gumussagbil.645493

Abstract

Nutrition is the primary intrauterine
environmental factor, altering fetal genome expression that may have lifelong
consequences. During the maternal period, very low or high energy intake,
higher protein and fat intake may increase obesity risk in offspring. Although
this varies by gender, female infants are more vulnerable than males.
Generally, adequate and balanced protein and energy intake during the pregnancy
can be protective against obesity in adulthood.

While adequate iron, chromium,
folic acid, vitamin B12 supplements taken during early pregnancy can
prevent obesity in offspring, methyl vitamins such as excessive vitamin B12,
folic acid and multivitamin intake can also increase the risk of obesity.
Present maternal obesity or excessive body weight gain during pregnancy, especially
in the first trimester, increases the risk of obesity and complications in
offspring.

There is a U-shaped correlation
between birth weight and BMI, waist circumference and body fat percentage.
Studies have shown that both high and low birth weights are associated with an
increased obesity risk later in life. Optimal maternal nutrition can reduce
obesity risk by affecting birth weight and mother's body weight gain during
pregnancy. Encouraging optimal nutrition not only ensures optimal fetal development,
but also reduces the obesity risk later in life.







This review article aims to
summarize the relationship between maternal nutrition and maternal body weight
gain in pregnancy, mother's body weight and baby's birth weight and the
development of obesity in later periods of life, such as childhood and
adulthood.

References

  • Mazzeo, S.E., Slof-Op’t Landt M.C., Jones, I., Mitchell, K., Kendler, K.S., Neale, M.C. ve ark. (2006). ‘Associations among postpartum depression, eating disorders, and perfectionism in a population-based sample of adult women’. International Journal of Eating Disorders, 39(3), 202-211.
  • Güngör, N.K. (2014). ‘Overweight and obesity in children and adolescents’. Journal of clinical research in pediatric endocrinology, 6(3), 129-143.
  • Muhlhausler, B.S. ve Ong Z.Y. (2011). ‘The fetal origins of obesity: early origins of altered food intake’. Endocr Metab Immune Disord Drug Targets, 11(3), 189-97.
  • Hu, X.F., G.G. Liu, ve M. Fan. (2017). ‘Long-Term Effects of Famine on Chronic Diseases: Evidence from China's Great Leap Forward Famine’. Health Economics, 26(7), 922-936.
  • Chang, Guo-Qing, C., Gaysinskaya, V., Karatayev, O., Leibowitz S.F. (2008). ‘Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity’. Journal of Neuroscience, 28(46), 12107-12119.
  • Ong, Z.Y. ve Muhlhausler, B. (2011). ‘Maternal “junk-food” feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring’. The FASEB Journal, 25(7), 2167-2179.
  • Groth, S.W., Holland, M.L., Smith J.A., Mng, Y., Kitzman, H. (2017). ‘Effect of Gestational Weight Gain and Prepregnancy Body Mass Index in Adolescent Mothers on Weight and Body Mass Index of Adolescent Offspring’. The Journal of adolescent health: official publication of the Society for Adolescent Medicine, 61(5), 626-633.
  • Gillman, M.W., Rifas-Shiman, S., Berkey, C.S., Field, A.E., Colditz, G.A. (2003). ‘Maternal gestational diabetes, birth weight, and adolescent obesity’. Pediatrics, 111(3), e221-e226.
  • Gluckman, P.D., Hanson, M.A., Morton, S.M., Pinal, C.S. ‘Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate, 2005. 87(2), 127-139.
  • Maffeis, C. ve Morandi, A. (2017). ‘Effect of Maternal Obesity on Foetal Growth and Metabolic Health of the Offspring’. Obesity facts, 10(2), 112-117.
  • Elshenawy, S. ve Simmons, R. (2016). ‘Maternal obesity and prenatal programming’. Molecular and Cellular Endocrinology, 435, 2-6.
  • Lemes, S.F., de Souza, A.C.P., Payolla, T.B., Versutti, M.D., de Fatima da Silva Ramalho, A., Mendes-da-Silva, C. ve ark. (2018). ‘Maternal Consumption of High-fat Diet in Mice Alters Hypothalamic Notch Pathway, NPY Cell Population and Food Intake in Offspring’. Neuroscience, 371, 1-15.
  • Yeo, G.S. ve Heisler, L.K. (2012). ‘Unraveling the brain regulation of appetite: lessons from genetics’. Nat Neurosci, 15(10), 1343-1349.
  • Sun, B., Prcell, R.H., Terrilllion, C.E., Yan, J., Moran, T.H., Tamashiro, K.L. (2012. ‘Maternal high-fat diet during gestation or suckling differentially affects offspring leptin sensitivity and obesity’. Diabetes, 61(11), 2833-2841.
  • Grayson, B.E., Levasseur, P.R., Williams, S.M., Smirth, M.S., Marks, D.L., Grove, K.L. (2010). ‘Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet’. Endocrinology, 151(4), 1622-1632.
  • Maslova, E., Rytter, D., Bech, B.H., Henriksen, T.B., Rasmussen, M.A., Olsen, S.F. ve ark. (2014). ‘Maternal protein intake during pregnancy and offspring overweight 20 y later’. Am J Clin Nutr, 100(4), 1139-1148.
  • Lecoutre, S., Marousez, L., Drougard, A., Knauf, C., Guinez, C., Elberle, D. ve ark. (2017). ‘Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring’. Journal of Developmental Origins of Health and Disease, 8(1), 3-7.
  • Ravelli, G.P., Stein, Z.A. ve Susser, M.W. (1976). ‘Obesity in young men after famine exposure in utero and early infancy’. N Engl J Med, 295(7), 349-353.
  • Taylor, P.D. ve Poston, L. (2007). ‘Developmental programming of obesity in mammals’. Exp Physiol, 92(2), 287-298.
  • Starling, A.P., Sauder, K.A., Kaar, J.L., Shapiro, A.L., Siega-Riz, A.L., Dabelea, D. (2017). ‘Maternal Dietary Patterns during Pregnancy Are Associated with Newborn Body Composition’. The Journal of nutrition, 147(7), 1334-1339.
  • Brion, M.J.A., Ness A.R., Rogers, I., Emmet, P., Cribb, V., Smith G.D. ve ark. (2010). ‘Maternal macronutrient and energy intakes in pregnancy and offspring intake at 10 y: exploring parental comparisons and prenatal effects’. The American journal of clinical nutrition, 91(3), 748-756.
  • Lagishetty, V., Nandiwada, V.B., Kalashikam, R.R., Manchala, R. (2007). ‘Effect of maternal vitamin and mineral restrictions on the body fat content and adipocytokine levels of WNIN rat offspring’. Nutrition & metabolism, 4, 21-25.
  • Padmavathi, I.J., Rao, K.R., Venu, L., Ganeshan, M., Kumar, K.A., Rao, C.N. ve ark. (2010). ‘Chronic maternal dietary chromium restriction modulates visceral adiposity: probable underlying mechanisms’. Diabetes, 59(1), 98-104.
  • Padmavathi, I.J., Kishore, Y.D., Venu, L., Ganeshan, M., Harishankar, N., Giridharan, N.V. ve ark. (2009). ‘Prenatal and perinatal zinc restriction: effects on body composition, glucose tolerance and insulin response in rat offspring’. Exp Physiol, 94(6), 761-769.
  • Pannia, E., Clara, E.C., Kubant, R., Sanchez-Hernandez, D., Huot, P.S.P., Anderson, G.H. (2016). ‘Role of maternal vitamins in programming health and chronic disease’. Nutrition reviews, 74(3), 166-180.
  • Kumar, K.A., Lalitha, A., Pavithra, D., Padmavathi, I.J., Ganeshan, M., Rao, K.R. ve ark. (2013). ‘Maternal dietary folate and/or vitamin B12 restrictions alter body composition (adiposity) and lipid metabolism in Wistar rat offspring’. J Nutr Biochem, 24(1), 25-31.
  • Yajnik, C.S., Deshpande, S.S., Jackson, A.A., Refsum, H., Rao, S., Fisher, D.J. ve ark. (2008). ‘Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study’. Diabetologia, 51(1), 29-38.
  • Alwan, N.A. ve Hamamy, H. (2015). ‘Maternal Iron Status in Pregnancy and Long-Term Health Outcomes in the Offspring’. J Pediatr Genet, 4(2), 111-123.
  • Zhang, J., Lewis, R.M., Wang, C., Hales, N., Byrne, C.D. (2005). ‘Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses’. Am J Physiol Regul Integr Comp Physiol, 288(1), R104-111.
  • Belenchia, A.M., Johnson, S.A., Ellersieck, M.R., Rosenfeld, C.S., Peterson, C.A. (2017). ‘In utero vitamin D deficiency predisposes offspring to long-term adverse adipose tissue effects’. J Endocrinol, 234(3), 301-313.
  • Cerit, Z. (2017). ‘Maternal depression, vitamin D, and offspring obesity’. The Journal of Pediatrics, 182, 407-408.
  • The SWS Study Group. (2012). ‘Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women’s Survey’. The American Journal of Clinical Nutrition, 96(1), 57-63.
  • Huypens, P., Sass, S., Wu, M., Dyckhoff, D., Tschöp, M., Theis, F. ve ark. (2016). ‘Epigenetic germline inheritance of diet-induced obesity and insulin resistance’. Nat Genet, 48(5), 497-499.
  • Glastras, Sarah J., Chen, H., Pollock, C.A., Saad, S. (2018). ‘Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring’. Bioscience Reports, 38(2), BSR20180050.
  • Diemert, A., Lezius, S., Pagenkemper, M., Hansen, G., Drozdowska, A. Hecker, K. ve ark. (2016). ‘Maternal nutrition, inadequate gestational weight gain and birth weight: results from a prospective birth cohort’. BMC Pregnancy Childbirth, 16, 224.
  • Kral, J.G., Biron, S., Simard, S., Hould, F.S., Lebel, S., Marceau, S. ve ark. (2006). ‘Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years’. Pediatrics, 118(6), e1644-e1649.
  • Daşıkan, Z. and Kavlak, O. (2009). ‘Maternal Obezite: Gebelik komplikasyonları ve gebe kadının yönetimi’. Turkiye Klinikleri Journal of Nursing Sciences, 1(1), 39-46.
  • Karachaliou, M., Georgiou, V., Roumeliotaki, T., Chaldiaki, G., Daraki, V., Koınaki, S. ve ark. (2015). ‘Association of trimester-specific gestational weight gain with fetal growth, offspring obesity, and cardiometabolic traits in early childhood’. Am J Obstet Gynecol, 2015. 212(4), 502.e1-502.14.
  • Switkowski, K.M., Jacques, P.F., Must, A., Kleinmen, K.P., Gillman, M.W., Oken, E. (2016). ‘Maternal protein intake during pregnancy and linear growth in the offspring’. Am J Clin Nutr, 104(4), 1128-1136.
  • Jornayvaz, F.R., Vollenweider, P., Bochud, M., Mooser, V., Waeber, G., Marques-Vidal, P. (2016). ‘Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study’. Cardiovascular Diabetology, 15 (1), 73.

Maternal Beslenme ve İlerleyen Yaşamda Obezite

Year 2020, Volume: 9 Issue: 1, 36 - 43, 02.04.2020
https://doi.org/10.37989/gumussagbil.645493

Abstract

  Beslenme fetal
genomun ekspresyonunu değiştiren ve yaşam boyu sonuçları olabilecek ana
intrauterin çevresel faktördür. Maternal dönemde, çok düşük veya yüksek enerji
alımı, daha yüksek protein ve yağ alımı yenidoğanlarda obezite riskini
arttırabilir. Bu durum cinsiyete göre değişmekle birlikte kızlar erkeklere göre
daha savunmasızdır. Genel olarak gebelik sırasında yeterli ve dengeli protein
ve enerji alımı yetişkin obezitesi için koruyucu bir faktör olabilir.



Gebeliğin erken
dönemlerinden itibaren yeterli demir, krom, folik asit, vitamin B12 takviyeleri
yenidoğanlarda obeziteyi önleyebilirken, aşırı folik asit, vitamin B12
gibi metil vitaminleri ile aşırı multivitamin alımı da obezite riskini
arttırabilir. Annedeki mevcut obezite veya gebelik sırasındaki özellikle de ilk
trimesterdeki aşırı vücut ağırlığı kazanımı da birçok komplikasyonun yanında yenidoğanlarda
obez olma riskini de arttırır.



Doğum ağırlığı ile BKİ, bel çevresi ve
vücut yağ yüzdesi arasında U-şeklinde bir ilişki vardır. Yapılan çalışmalarda
hem yüksek doğum ağırlığının hem de düşük doğum ağırlığının sonraki yaşamda
obezite riski ile ilişkili olduğu gösterilmiştir. Optimal maternal beslenme
doğum ağırlığını ve annenin gebelik sırasındaki vücut ağırlığı kazanımını
etkileyerek obezite riskini azaltabilir. Optimal beslenmeyi teşvik etmek sadece
optimal fetal gelişimi sağlamakla kalmaz, aynı zamanda ilerleyen dönemde
obezite gelişme riskini de azaltır.



Bu derleme makalenin amacı, gebelikte
maternal beslenme ve maternal vücut ağırlığı kazanımı, annenin vücut ağırlığı
ve bebek doğum ağırlığı ile çocukluk, erişkinlik gibi ilerleyen dönemde obezite
gelişimi ile olan ilişkilerini yapılan çalışmalar eşliğinde özetlemektir.

References

  • Mazzeo, S.E., Slof-Op’t Landt M.C., Jones, I., Mitchell, K., Kendler, K.S., Neale, M.C. ve ark. (2006). ‘Associations among postpartum depression, eating disorders, and perfectionism in a population-based sample of adult women’. International Journal of Eating Disorders, 39(3), 202-211.
  • Güngör, N.K. (2014). ‘Overweight and obesity in children and adolescents’. Journal of clinical research in pediatric endocrinology, 6(3), 129-143.
  • Muhlhausler, B.S. ve Ong Z.Y. (2011). ‘The fetal origins of obesity: early origins of altered food intake’. Endocr Metab Immune Disord Drug Targets, 11(3), 189-97.
  • Hu, X.F., G.G. Liu, ve M. Fan. (2017). ‘Long-Term Effects of Famine on Chronic Diseases: Evidence from China's Great Leap Forward Famine’. Health Economics, 26(7), 922-936.
  • Chang, Guo-Qing, C., Gaysinskaya, V., Karatayev, O., Leibowitz S.F. (2008). ‘Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity’. Journal of Neuroscience, 28(46), 12107-12119.
  • Ong, Z.Y. ve Muhlhausler, B. (2011). ‘Maternal “junk-food” feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring’. The FASEB Journal, 25(7), 2167-2179.
  • Groth, S.W., Holland, M.L., Smith J.A., Mng, Y., Kitzman, H. (2017). ‘Effect of Gestational Weight Gain and Prepregnancy Body Mass Index in Adolescent Mothers on Weight and Body Mass Index of Adolescent Offspring’. The Journal of adolescent health: official publication of the Society for Adolescent Medicine, 61(5), 626-633.
  • Gillman, M.W., Rifas-Shiman, S., Berkey, C.S., Field, A.E., Colditz, G.A. (2003). ‘Maternal gestational diabetes, birth weight, and adolescent obesity’. Pediatrics, 111(3), e221-e226.
  • Gluckman, P.D., Hanson, M.A., Morton, S.M., Pinal, C.S. ‘Life-long echoes--a critical analysis of the developmental origins of adult disease model. Biol Neonate, 2005. 87(2), 127-139.
  • Maffeis, C. ve Morandi, A. (2017). ‘Effect of Maternal Obesity on Foetal Growth and Metabolic Health of the Offspring’. Obesity facts, 10(2), 112-117.
  • Elshenawy, S. ve Simmons, R. (2016). ‘Maternal obesity and prenatal programming’. Molecular and Cellular Endocrinology, 435, 2-6.
  • Lemes, S.F., de Souza, A.C.P., Payolla, T.B., Versutti, M.D., de Fatima da Silva Ramalho, A., Mendes-da-Silva, C. ve ark. (2018). ‘Maternal Consumption of High-fat Diet in Mice Alters Hypothalamic Notch Pathway, NPY Cell Population and Food Intake in Offspring’. Neuroscience, 371, 1-15.
  • Yeo, G.S. ve Heisler, L.K. (2012). ‘Unraveling the brain regulation of appetite: lessons from genetics’. Nat Neurosci, 15(10), 1343-1349.
  • Sun, B., Prcell, R.H., Terrilllion, C.E., Yan, J., Moran, T.H., Tamashiro, K.L. (2012. ‘Maternal high-fat diet during gestation or suckling differentially affects offspring leptin sensitivity and obesity’. Diabetes, 61(11), 2833-2841.
  • Grayson, B.E., Levasseur, P.R., Williams, S.M., Smirth, M.S., Marks, D.L., Grove, K.L. (2010). ‘Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet’. Endocrinology, 151(4), 1622-1632.
  • Maslova, E., Rytter, D., Bech, B.H., Henriksen, T.B., Rasmussen, M.A., Olsen, S.F. ve ark. (2014). ‘Maternal protein intake during pregnancy and offspring overweight 20 y later’. Am J Clin Nutr, 100(4), 1139-1148.
  • Lecoutre, S., Marousez, L., Drougard, A., Knauf, C., Guinez, C., Elberle, D. ve ark. (2017). ‘Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring’. Journal of Developmental Origins of Health and Disease, 8(1), 3-7.
  • Ravelli, G.P., Stein, Z.A. ve Susser, M.W. (1976). ‘Obesity in young men after famine exposure in utero and early infancy’. N Engl J Med, 295(7), 349-353.
  • Taylor, P.D. ve Poston, L. (2007). ‘Developmental programming of obesity in mammals’. Exp Physiol, 92(2), 287-298.
  • Starling, A.P., Sauder, K.A., Kaar, J.L., Shapiro, A.L., Siega-Riz, A.L., Dabelea, D. (2017). ‘Maternal Dietary Patterns during Pregnancy Are Associated with Newborn Body Composition’. The Journal of nutrition, 147(7), 1334-1339.
  • Brion, M.J.A., Ness A.R., Rogers, I., Emmet, P., Cribb, V., Smith G.D. ve ark. (2010). ‘Maternal macronutrient and energy intakes in pregnancy and offspring intake at 10 y: exploring parental comparisons and prenatal effects’. The American journal of clinical nutrition, 91(3), 748-756.
  • Lagishetty, V., Nandiwada, V.B., Kalashikam, R.R., Manchala, R. (2007). ‘Effect of maternal vitamin and mineral restrictions on the body fat content and adipocytokine levels of WNIN rat offspring’. Nutrition & metabolism, 4, 21-25.
  • Padmavathi, I.J., Rao, K.R., Venu, L., Ganeshan, M., Kumar, K.A., Rao, C.N. ve ark. (2010). ‘Chronic maternal dietary chromium restriction modulates visceral adiposity: probable underlying mechanisms’. Diabetes, 59(1), 98-104.
  • Padmavathi, I.J., Kishore, Y.D., Venu, L., Ganeshan, M., Harishankar, N., Giridharan, N.V. ve ark. (2009). ‘Prenatal and perinatal zinc restriction: effects on body composition, glucose tolerance and insulin response in rat offspring’. Exp Physiol, 94(6), 761-769.
  • Pannia, E., Clara, E.C., Kubant, R., Sanchez-Hernandez, D., Huot, P.S.P., Anderson, G.H. (2016). ‘Role of maternal vitamins in programming health and chronic disease’. Nutrition reviews, 74(3), 166-180.
  • Kumar, K.A., Lalitha, A., Pavithra, D., Padmavathi, I.J., Ganeshan, M., Rao, K.R. ve ark. (2013). ‘Maternal dietary folate and/or vitamin B12 restrictions alter body composition (adiposity) and lipid metabolism in Wistar rat offspring’. J Nutr Biochem, 24(1), 25-31.
  • Yajnik, C.S., Deshpande, S.S., Jackson, A.A., Refsum, H., Rao, S., Fisher, D.J. ve ark. (2008). ‘Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study’. Diabetologia, 51(1), 29-38.
  • Alwan, N.A. ve Hamamy, H. (2015). ‘Maternal Iron Status in Pregnancy and Long-Term Health Outcomes in the Offspring’. J Pediatr Genet, 4(2), 111-123.
  • Zhang, J., Lewis, R.M., Wang, C., Hales, N., Byrne, C.D. (2005). ‘Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses’. Am J Physiol Regul Integr Comp Physiol, 288(1), R104-111.
  • Belenchia, A.M., Johnson, S.A., Ellersieck, M.R., Rosenfeld, C.S., Peterson, C.A. (2017). ‘In utero vitamin D deficiency predisposes offspring to long-term adverse adipose tissue effects’. J Endocrinol, 234(3), 301-313.
  • Cerit, Z. (2017). ‘Maternal depression, vitamin D, and offspring obesity’. The Journal of Pediatrics, 182, 407-408.
  • The SWS Study Group. (2012). ‘Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women’s Survey’. The American Journal of Clinical Nutrition, 96(1), 57-63.
  • Huypens, P., Sass, S., Wu, M., Dyckhoff, D., Tschöp, M., Theis, F. ve ark. (2016). ‘Epigenetic germline inheritance of diet-induced obesity and insulin resistance’. Nat Genet, 48(5), 497-499.
  • Glastras, Sarah J., Chen, H., Pollock, C.A., Saad, S. (2018). ‘Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring’. Bioscience Reports, 38(2), BSR20180050.
  • Diemert, A., Lezius, S., Pagenkemper, M., Hansen, G., Drozdowska, A. Hecker, K. ve ark. (2016). ‘Maternal nutrition, inadequate gestational weight gain and birth weight: results from a prospective birth cohort’. BMC Pregnancy Childbirth, 16, 224.
  • Kral, J.G., Biron, S., Simard, S., Hould, F.S., Lebel, S., Marceau, S. ve ark. (2006). ‘Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years’. Pediatrics, 118(6), e1644-e1649.
  • Daşıkan, Z. and Kavlak, O. (2009). ‘Maternal Obezite: Gebelik komplikasyonları ve gebe kadının yönetimi’. Turkiye Klinikleri Journal of Nursing Sciences, 1(1), 39-46.
  • Karachaliou, M., Georgiou, V., Roumeliotaki, T., Chaldiaki, G., Daraki, V., Koınaki, S. ve ark. (2015). ‘Association of trimester-specific gestational weight gain with fetal growth, offspring obesity, and cardiometabolic traits in early childhood’. Am J Obstet Gynecol, 2015. 212(4), 502.e1-502.14.
  • Switkowski, K.M., Jacques, P.F., Must, A., Kleinmen, K.P., Gillman, M.W., Oken, E. (2016). ‘Maternal protein intake during pregnancy and linear growth in the offspring’. Am J Clin Nutr, 104(4), 1128-1136.
  • Jornayvaz, F.R., Vollenweider, P., Bochud, M., Mooser, V., Waeber, G., Marques-Vidal, P. (2016). ‘Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study’. Cardiovascular Diabetology, 15 (1), 73.
There are 40 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Derlemeler
Authors

Fatma Tayhan Kartal 0000-0001-8524-9048

Gizem Helvacı

Nurcan Yabancı Ayhan This is me 0000-0003-1233-246X

Publication Date April 2, 2020
Published in Issue Year 2020 Volume: 9 Issue: 1

Cite

APA Tayhan Kartal, F., Helvacı, G., & Yabancı Ayhan, N. (2020). Maternal Beslenme ve İlerleyen Yaşamda Obezite. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 9(1), 36-43. https://doi.org/10.37989/gumussagbil.645493
AMA Tayhan Kartal F, Helvacı G, Yabancı Ayhan N. Maternal Beslenme ve İlerleyen Yaşamda Obezite. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. April 2020;9(1):36-43. doi:10.37989/gumussagbil.645493
Chicago Tayhan Kartal, Fatma, Gizem Helvacı, and Nurcan Yabancı Ayhan. “Maternal Beslenme Ve İlerleyen Yaşamda Obezite”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 9, no. 1 (April 2020): 36-43. https://doi.org/10.37989/gumussagbil.645493.
EndNote Tayhan Kartal F, Helvacı G, Yabancı Ayhan N (April 1, 2020) Maternal Beslenme ve İlerleyen Yaşamda Obezite. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 9 1 36–43.
IEEE F. Tayhan Kartal, G. Helvacı, and N. Yabancı Ayhan, “Maternal Beslenme ve İlerleyen Yaşamda Obezite”, Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 9, no. 1, pp. 36–43, 2020, doi: 10.37989/gumussagbil.645493.
ISNAD Tayhan Kartal, Fatma et al. “Maternal Beslenme Ve İlerleyen Yaşamda Obezite”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 9/1 (April 2020), 36-43. https://doi.org/10.37989/gumussagbil.645493.
JAMA Tayhan Kartal F, Helvacı G, Yabancı Ayhan N. Maternal Beslenme ve İlerleyen Yaşamda Obezite. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2020;9:36–43.
MLA Tayhan Kartal, Fatma et al. “Maternal Beslenme Ve İlerleyen Yaşamda Obezite”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 9, no. 1, 2020, pp. 36-43, doi:10.37989/gumussagbil.645493.
Vancouver Tayhan Kartal F, Helvacı G, Yabancı Ayhan N. Maternal Beslenme ve İlerleyen Yaşamda Obezite. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2020;9(1):36-43.