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Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs

Year 2018, Volume: 10 Issue: 4, 191 - 195, 01.09.2018

Abstract

Kanser dünya üzerinde ölüm nedenleri arasında ikinci sırada yer almaktadır. Kanser hastalarında normal popülasyona oranla serebrovasküler hastalık gelişme riskinde artış izlenmektedir. Kanser ilişkili mekanizmalar içinde hiperkoagülasyon, tümör embolizmi ve tümör hücrelerinden salınan sitokinlerin (TNF ve İL) yarattığı vasküler endoteliyal doku hasarının yer aldığı ve hiperkogülopatinin önemli bir kısmından sorumlu olduğu görülmektedir. Bu olguda da akciğer kanseri beyin metastazı olan hastada serebral enfarktüs gelişmiştir. İntrakranial tümör embolisi nedeniyle oluşan serebral enfarktüs nadir görülen vakalardandır.

References

  • 1. Graus F, Rogers LR, Posner JB. Cerebrovascular complications in patients with cancer. Medicine (Baltimore) 1985;64:16-35.
  • 2. Dipasco PJ, Misra S, Koniaris LG, Moffat FL Jr. Thrombophilic state in cancer, part I: Biology, incidence, and risk factors. J Surg Oncol 2011;104(3):316-22.
  • 3. Donati MB.Thrombosis and cancer: Trousseau syndrome revisited. Best Pract Res Clin Haematol 2009;22(1):3-8. 4. Chen PC, Muo CH, Lee YT, Yu YH, Sung FC. Lung cancer and incidence of stroke: A population-based cohort study. Stroke 2011;42(11):3034-9.
  • 4. Kim SJ, Park JH, Lee MJ, et al. Clues to occult cancer in patients with ischemic stroke. PLoS One 2012;7:e44959.
  • 5. Navi BB, DeAngelis LM, Segal AZ. Multifocal strokes as the presentation of occult lung cancer. J Neurooncol 2007;85:307-9.
  • 6. Seok JM, Kim SG, Kim JW, et al. Coagulopathy and embolic signal in cancer patients with ischemic stroke. Ann Neurol 2010;68:213-9.
  • 7. Kim SG, Hong JM, Kim HY, et al. Ischemic stroke in cancer patients with and without conventional mechanisms: a multicenter study in Korea. Stroke 2010;41:798-801.
  • 8. Mai H, Xia J, Wu Y, et al. Clinical presentation and imaging characteristics of occult lung cancera ssociated ischemic stroke. J Clin Neurosci 2015;22:296-302.
  • 9. Navi BB, Reichman JS, Berlin D, et al. Intracerebral and subarachnoid hemorrhage in patients with cancer. Neurology 2010;74:494-501. 10- Chen PC, Muo CH, Lee YT, Yu YH, Sung FC. Lung cancer and incidence of stroke: A population-based cohort study. Stroke 2011;42(11):3034-9.

Cerebral Infarction After Lung Cancer Brain Metastasis

Year 2018, Volume: 10 Issue: 4, 191 - 195, 01.09.2018

Abstract

Cancer is the second leading cause of death in the world. There is an increase in the risk of development of cerebrovascular disease in cancer patients compared to the normal population. Cancer-related mechanisms include hypercoagulation, tumor embolism, and vascular endothelial tissue damage caused by cytokines (TNF and IL) released from tumor cells, and are responsible for a significant portion of hypercogulopathyIn this case, cerebral infarction developed in the patient with lung cancer brain metastasis. Cerebral infarction due to intracranial tumor embolism is one of the rare cases

References

  • 1. Graus F, Rogers LR, Posner JB. Cerebrovascular complications in patients with cancer. Medicine (Baltimore) 1985;64:16-35.
  • 2. Dipasco PJ, Misra S, Koniaris LG, Moffat FL Jr. Thrombophilic state in cancer, part I: Biology, incidence, and risk factors. J Surg Oncol 2011;104(3):316-22.
  • 3. Donati MB.Thrombosis and cancer: Trousseau syndrome revisited. Best Pract Res Clin Haematol 2009;22(1):3-8. 4. Chen PC, Muo CH, Lee YT, Yu YH, Sung FC. Lung cancer and incidence of stroke: A population-based cohort study. Stroke 2011;42(11):3034-9.
  • 4. Kim SJ, Park JH, Lee MJ, et al. Clues to occult cancer in patients with ischemic stroke. PLoS One 2012;7:e44959.
  • 5. Navi BB, DeAngelis LM, Segal AZ. Multifocal strokes as the presentation of occult lung cancer. J Neurooncol 2007;85:307-9.
  • 6. Seok JM, Kim SG, Kim JW, et al. Coagulopathy and embolic signal in cancer patients with ischemic stroke. Ann Neurol 2010;68:213-9.
  • 7. Kim SG, Hong JM, Kim HY, et al. Ischemic stroke in cancer patients with and without conventional mechanisms: a multicenter study in Korea. Stroke 2010;41:798-801.
  • 8. Mai H, Xia J, Wu Y, et al. Clinical presentation and imaging characteristics of occult lung cancera ssociated ischemic stroke. J Clin Neurosci 2015;22:296-302.
  • 9. Navi BB, Reichman JS, Berlin D, et al. Intracerebral and subarachnoid hemorrhage in patients with cancer. Neurology 2010;74:494-501. 10- Chen PC, Muo CH, Lee YT, Yu YH, Sung FC. Lung cancer and incidence of stroke: A population-based cohort study. Stroke 2011;42(11):3034-9.
There are 9 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Case Report
Authors

Mehmet Murat Dişçi

Fatih Ersay Deniz This is me

Erol Öksüz This is me

Özgür Demir This is me

Publication Date September 1, 2018
Published in Issue Year 2018 Volume: 10 Issue: 4

Cite

APA Dişçi, M. M., Deniz, F. E., Öksüz, E., Demir, Ö. (2018). Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi, 10(4), 191-195.
AMA Dişçi MM, Deniz FE, Öksüz E, Demir Ö. Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs. Gaziosmanpaşa Tıp Dergisi. September 2018;10(4):191-195.
Chicago Dişçi, Mehmet Murat, Fatih Ersay Deniz, Erol Öksüz, and Özgür Demir. “Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10, no. 4 (September 2018): 191-95.
EndNote Dişçi MM, Deniz FE, Öksüz E, Demir Ö (September 1, 2018) Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10 4 191–195.
IEEE M. M. Dişçi, F. E. Deniz, E. Öksüz, and Ö. Demir, “Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs”, Gaziosmanpaşa Tıp Dergisi, vol. 10, no. 4, pp. 191–195, 2018.
ISNAD Dişçi, Mehmet Murat et al. “Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10/4 (September 2018), 191-195.
JAMA Dişçi MM, Deniz FE, Öksüz E, Demir Ö. Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs. Gaziosmanpaşa Tıp Dergisi. 2018;10:191–195.
MLA Dişçi, Mehmet Murat et al. “Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi, vol. 10, no. 4, 2018, pp. 191-5.
Vancouver Dişçi MM, Deniz FE, Öksüz E, Demir Ö. Akciğer Kanseri Beyin Metastazı Sonrası Serebral Enfarktüs. Gaziosmanpaşa Tıp Dergisi. 2018;10(4):191-5.

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