Nötrofil/Lenfosit Oranının Postoperatif Ağrı İçin Öngörücü Rolü

Yıl 2022, Cilt: 14 Sayı: 2, 110 - 117, 27.10.2022

Vildan Kölükçü , Mürsel Kahveci

Öz

Amaç: Ameliyat sonrası ağrı, cerrahi işlemin neden olduğu akut inflamasyon ile yakından ilişkilidir. Çalışmamızda, sistemik bir inflamasyon belirteci olarak nötrofil/lenfosit oranı (NLR) ile postoperatif ağrının belirteci olarak postoperatif analjezik tüketimi arasındaki ilişkiyi araştırmak amaçlandı.
Gereç ve Yöntem: Çalışmada 18-55 yaşları arasında genel anestezi altında septorinoplasti uygulanan olguların verileri analiz edildi ve American Society of Anesthesiologists (ASA) sınıflamasına göre sınıf I-II olarak değerlendirildi. Hastaların demografik verileri, ASA skorları, operasyon süresi ve postoperatif dönemdeki toplam analjezik tüketimi kaydedildi. Hastalar preoperatif NLO'ya göre iki gruba ayrıldı. Buna göre NLO <2 olan hastalar Grup 1, NLO ≥2 olan hastalar Grup 2 idi.
Bulgular: Çalışmaya toplam 116 vaka dahil edildi. Demografik veriler ve operasyon süreleri açısından iki grup arasında istatistiksel olarak anlamlı fark yoktu (p>0.05). Grup 1 ve 2'de ortalama NLR sırasıyla 1,46±0,29 ve 2,64±0,74 idi. Grup 2'nin, Grup 1'e göre istatistiksel olarak anlamlı derecede yüksek postoperatif analjezik tüketimine sahip olduğu belirlendi (p=0,006).
Sonuç: Çalışmamızda elde edilen veriler ışığında ameliyat öncesi NLR'nın ameliyat sonrası ağrıyı öngörerek uygun tedavi stratejilerinin belirlenmesinde yol gösterici bir belirteç olarak değerlendirilebileceği sonucuna varıldı.

Anahtar Kelimeler

Nötrofil/lenfosit oranı, postoperatif ağrı, analjezik tüketimi, septorinoplasti

Predictive Role of Neutrophil/Lymphocyte Ratio for Postoperative Pain

Öz

Aim:Postoperative pain is closely associated with acute inflammation caused by the surgical procedure. In our study, the aim was to investigate the correlation between neutrophil/lymphocyte ratio (NLR) as a systemic inflammation markerwith postoperative analgesic consumption as a marker of postoperative pain.
Material and Method: The study analysed data from cases undergoing septorhinoplasty under general anaesthesia aged from 18-55 years and assessed as class I-II according to American Society of Anesthesiologists (ASA) classification. The demographic data of patients, ASA scores, operation duration and total analgesic consumptionin the postoperative period were recorded. Patients were divided into two groups according to preoperative NLR. Accordingly, patients with NLR <2 were Group 1, while patients with NLR ≥2 were Group 2.
Results: The study included a total of 116 cases. There were no statistically significant differences between the two groups in terms of demographic data and operation durations (p>0.05). The mean NLR in Groups 1 and 2 were 1.46±0.29 and 2.64±0.74, respectively. Group 2 were identified to have statistically significantly higher postoperative analgesic consumption compared to Group 1 (p=0.006).
Conclusion: In light of data obtained in our study, it was concluded that preoperative NLR may be assessed as a guiding marker for determination of appropriate treatment strategies by predicting postoperative pain.

Anahtar Kelimeler

Neutrophil/lymphocyte ratio, postoperative pain, analgesic consumption, septorhinoplasty

Kaynakça

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