Multivitamin, Vitamin E/Selenyum ve Prostaglandin Enjeksiyonlarının Kıvırcık Koyunlarının Üreme Performansı Üzerine Etkileri *

Abstract

Amaç: Bu çalışmada üreme mevsimine geçişte Kıvırcık ırkı koyunlarda döl verim performansı üzerine üç farklı ticari ürünün tek doz uygulanma etkinliği araştırılmıştır. Materyal ve Metot: Bu çalışmada 3-4 yaşlarında ve 50 ila 55 kg ağırlığında 98 Kıvırcık koyunu kullanılmıştır. Çalışmada kullanılan koyunlar rastgele dört farklı (PGF2α, Vit.E/Se, multivitamin ve kontrol) gruba ayrılmıştır. Tüm bu enjeksiyonlar koç katım sürecinden bir hafta önce tüm gruplara uygulanmıştır. Bulgular: Kontrol grubu ile uygulama grupları arasındaki fark istatistiksel olarak anlamlıydı (P < 0.01); ancak PGF2α ile Vit.E/Se ve multivitamin uygulamaları arasındaki fark çoğuz doğum oranı açısından önemsizdi (P > 0.05). Yavru büyüklüğü açısından en yüksek değer PGF2α grubunda bulunmuştur. Sonuç: Çalışmada, anöstrus döneminden üreme mevsimine geçişte Kıvırcık koyunlarında östrus ve gebeliği teşvik etmede her üç uygulama da kontrol grubundan daha başarılı olmuş ve tüm koyunlar sağlıklı bir şekilde doğum yapmıştır. Anahtar sözcükler: Koyun, üreme, PGF2α, vitamin E/Selenyum, vitamin A, vitamin D3, vitamin B

Keywords

• Koyun
• üreme
• PGF2α
• vitamin E/Selenyum
• vitamin A
• vitamin D3
• vitamin B

Effects of Multivitamin, Vitamin E/Selenium and Prostaglandin Injections on Reproductive Performance Kıvırcık Ewes

Abstract

Objective: This study investigated the effectiveness of the single-dose treatment of three different commercial products on reproductive performance in Kıvırcık ewes during the transition to the breeding season. Material and Methods: Ninety-eight Kıvırcık ewes aged 3-4 years and weighed from 50 to 55 kg have been used in this study. The ewes used in the study were randomly divided into four different (PGF2α, Vit.E/Se, multivitamin and control) groups. All these injections were applied to all groups one week before the ram-mating process. Results: The difference between the control group and the treatment groups was statistically significant (P < 0.01); however, the difference between PGF2α and Vit.E/Se, and multivitamin treatments was insignificant (P > 0.05) in terms of multiple-birth rate. The highest value in terms of litter size was found in the PGF2α treatment group. Conclusion: In the study, all three treatments were more successful than the control group in inducing estrus and pregnancy in Kıvırcık ewes during the transition from anoestrus period to the breeding season and all ewes healthily gave birth. Keywords: Sheep, reproduction, PGF2α, vitamin E/Selenium, vitamin A, vitamin D3, vitamin B

Keywords

• Sheep
• reproduction
• PGF2α
• vitamin E/Selenium
• vitamin A
• vitamin D3
• vitamin B

References

1. Abecia Ja, Forcada F, González–Bulnes A. 2012. Hormonal control of reproduction in small ruminants. Anim Reprod Sci, 130, 173–179.
2. Adnane M, Miroud K, Hanzen Ch, Kaidi R. 2018. The PGF2α, a less costly and invasive means than progestogens to manipulate the sexual activity in out–breeding season of the “Ouled Djellal” Algerian ewes. Livest Res Rural Dev, 30(11).
3. Abdelrahman MM, Al–Karablieh EK. 2002. Effect of vitamins AD3E injection on reproductive performance and net cash revenue of Awassi sheep raised under semi intensive system. J King Saud Univ, 14, 15–22.
4. Al–Asadi F Abd–Allah, Habib HN, Hassan AF. 2020. Effect of the injection of vitamins AD3E and the seasons on some blood traits, biochemical components and hormones of Arabi rams. J Anim Behav Biometeorol, 8, 74–81.
5. Amin BY, Dar RR, Ali A, Malla JA, Shubeena S. 2016. Role of micro–nutrients in bovine reproduction. Theriogenology Insight, 6(1), 57–65.
6. Ataman MB, Aköz M, Akman O. 2006. Induction of synchronized oestrus in Akkaraman cross–bred ewes during breeding and anestrus season, The use of short–term and long–term progesterone treatments, Revue Méd Vét, 157, 257–260.
7. Ayaseh M, Mirzaei A, Boostani A, Mehrvarz M. 2021. The effect of prostaglandin and gonadotrophins (GnRH and hCG) injection combined with the ram effect on progesterone concentrations and reproductive performance of Karakul ewes during the non‐breeding season. Vet Med Sci, 7, 148–155.
8. Awawdeh MA, Eljarah AH, Ababneh MM. 2019. Multiple injections of vitamin E and seleniumim proved the reproductive performance of estrus–synchronized Awassi ewes. Trop Anim Health Prod, 51, 1421–1426.

9. Birdane MK, Avdatek F. 2020. Effect of Vitamin A, D3, E Treatment on Fertility in the Pırlak Sheep. Kocatepe Vet J, 13(2), 79–184.
10. Chauhan S, Celi P, Leury B, Clarke I, Dunshea F. 2014. Dietary antioxidants at supranutritional doses improve oxidative status and reduce the negative effects of heat stress in sheep. Anim Sci, 92, 3364–3374.
11. Davis AJ, Fleet IR, Harrison FA, Walker FMM. 1980. Pulmonary metabolism of prostaglandin F2α in the conscious non‐pregnant ewe and sow. J Physiol, 301, 86.
12. Demiral ÖO, Abay M, Canooğlu E, Özalp GR, Rişvanli A. 2014. The combined effect of prostaglandin administration and ram introduction in multiparous and nulliparous sheep in anestrous period on prolificacy. Kafkas Vet Fak Derg, 20(5), 787–792.
13. Doğan I, Nur Z. 2006. Different estrous induction methods during the non–breeding season in Kıvırcık ewes. Vet Med, 51(4), 133–138.
14. Dursun Ş. 2019. Gonadotrophin stimulation of ewes that are not pregnant following multiple matings during the season. Turkish J Vet Anim Sci, 43, 39–43.
15. Fierro S, Gil J, Viñoles C, Olvera–Muzante J. 2013. The use of prostaglandins in controlling estrous cycle of the ewe, A review. Theriogenology, 79, 399–408.
16. Frank G. R., Bahr J. M., Easter RA. 1984. Riboflavin requirement of gestating swine. J Anim Sci, 59(6), 1567–1572.
17. Gabryszuk M, Klewiec J. 2002. Effect of injecting 2– and 3–year–old ewes with selenium and selenium–vitamin E on reproduction and rearing of lambs. Small Rumin Res, 43, 127–132.
18. Gonzalez–Bulnes A, Menchaca A, Martin GB, Martinez–Ros P. 2020. Seventy years of progestagen treatments for management of the sheep oestrous cycle, where we are and where we should go. Reprod Fertil Dev, 32(5), 441–452.
19. Hafez YM. 2012. Enhancing milk production in periparturient buffalo fed protected fat with and without vitamins AD3E treatment. Egyptian J Anim Prod, 49, 249–256.
20. Haliloğlu S, Serpek B. 2000. The effects of plasma vitamin C and ceruplasmin levels and exogenous vitamin C supplementation on reproduction in sheep. Turk. J Vet Anim Sci, 24, 403–412.
21. Hashem NM, Abd–Elrazek D, Abo–Elezz ZR, Latif MGA. 2016. Department Effect of vitamin A or C on physiological and reproductive response of Rahmani ewes during subtropical summer breeding season. Small Rumin Res, 144, 313–319.
22. Hefnawy AEG, Tórtora–Pérez JL. 2010. The importance of selenium and the effects of its deficiency in animal health. Small Rumin Res, 89, 185–192.
23. Hemingway RG. 2003. The influences of dietary intakes and supplementation with selenium and vitamin E on reproduction diseases and reproductive efficiency in cattle and sheep. Vet Res Commun, 27, 159–174.
24. Jindal R, Cosgrove JR, Aherne FX, Foxcroft GR. 1996. Effect of nutrition on embryonal mortality in gilts, Association with progesterone. J Anim Sci, 74(3), 620–624.
25. Kamiloğlu NN, Beytut E, Güven A, Altinsaat C. 2006. Changes in the erythrocyte anti–oxidant system of offspring of dams treated with Vitamin A and β–carotene during gestation. Small Rumin Res, 65, 142–148.
26. Kaymakçı M. 2006. Üreme Biyolojisi. Ege Üniversitesi Ziraat Fakültesi Yayın no: 503, İzmir.
27. Köse M, Kırbaș M, Dursun S, Bayril T. 2013. The effect of injections of β–carotene or vitamin E+Selenium on fertility in ewes in anestrus season. YYU Vet Fac Derg, 24, 83–86.
28. Koyuncu M, Yerlikaya H. 2007. Effect of selenium–vitamin E injections of ewes on reproduction and growth of their lambs. S Afr J Anim Sci, 37, 233–236.
29. Kuru M, Ögün M, Oral H, Kükürt A, Makav M, Kulaksız R. 2016. The use of controlled internal drug release for synchronization augmented oxidative and nitrosative stress and leptin levels in Georgian goats. JCNOS, 8, 541–542.
30. Kuru M, Sogukpinar O, Makav M, Centin N. 2017. Effect of barium selenate injections on fertility of Pirlak ewes subjected to estrus synchronization during non–breeding season. Med Vet, 73, 479–482.
31. Marai IFM, El– Darawany AA, Fadiel A, Abdel–Hafez MAM. 2008. Reproductive performance traits as affected by heat stress and its alleviation in sheep. Trop Subtrop Agroecosyst, 8, 209–234.
32. Minitab. 2019. Minitab® 19 Statistical Software. www.minitab.com/en–us/
33. Mirzaei A, Mohebbi–Fani M, Omidi A, Boostani A, Nazifi S, Mahmoodian–Fard HR, Chahardahcherik M. 2017. Progesterone concentration and lambing rate of Karakul ewes treated with prostaglandin and GnRH combined with the ram effect during breeding and non–breeding seasons. Theriogenology, 100, 120–125.
34. Munoz C, Carson AF, McCoy MA, Dawson LER, O'Connell NE, Gordon AW. 2008. Nutritional status of adult ewes during early and mid–pregnancy. 2. Effects of supplementation with selenised yeast on ewe reproduction and offspring performance to weaning. Animal, 2, 64–72.
35. Murdoch WJ, Martinchict JF. 2004. Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation, Carcinogenic implication and chemoprevention. Exp Biol Med, 229, 546–552.
36. Musa SI, Bitto II, Ayoade JA, Oyedipe OE. 2018. Effects of vitamin E and selenium on fertility and lamb performance of Yankasa sheep. Open J Vet Med, 8, 167–173.
37. Nayyar S, Jindal R. 2010 Essentiality of antioxidant vitamins for ruminants in relation to stress and reproduction. Iran J Vet Res, 11(1), 1–9.
38. Öziş Altınçekiç Ş, Koyuncu M. 2017. Comparison of effects of CIDR and prostaglandin applications on the reproductive performance of Kıvırcık ewes in anestrous. J Tekirdag Agric Fac, 14(1), 9–15.
39. Öziş Altınçekiç Ş, Dalyan Cilo B, Duru S, Koyuncu M. 2021. Investigation of the effect of intravaginal device–type and treatment–duration on vaginal features in ewes and determination of antibiotic susceptibility. Indian J Anim Res, 55(8), 924–929.
40. Ramírez–Bribiesca E, Hernandez–Camacho E, Hernandez–Calva LM, Tortora–Perez JL. 2004. Effect of parenteral supplement with sodium selenite on lamb mortality and hematic values of selenium. Agrociencia, 38(1), 43–51.
41. Rooke JA, Dwyer CM, Ashworth CJ. 2008. The potential for improving physiological, behavioural and immunological responses in the neonatal lamb by trace element and vitamin supplementation of the ewe. Animal, 2, 514–524.
42. Sönmez M, Bozkurt T, Türk G, Gür S. Kizil M, Yüce A. 2009. The effect of vitamin E treatment during preovulatory period on reproductive performance of goats following oestrus synchronization using intravaginal sponges. Anim Reprod Sci, 114, 183–192.
43. Surai PF. 2006. Selenium in nutrition and health. Nottingham University Press, 1st published, ISBN 1–904761–16–X, 974 pp.
44. Swelum AAA, Alowaimer AN, Abouheif MA. 2015. Use of fluorogestone acetate sponges or controlled internal drug release for estrus synchronization in ewes, Effects of hormonal profiles and reproductive performance. Theriogenology, 84, 498–503.
45. Titi HH, Kridli RT, Alnimer MA. 2010. Estrous synchronization in sheep and goats using combination of GnRH, progestagen and prostaglandin F2α. Reprod Dom Anim, 45, 594–599.
46. Ullah H, Khan RU, Tufarelli V, Laudadio V. 2020. Selenium, An essential micronutrient for sustainable dairy cows production. Sustainability, 12(24), 10693.
47. Vijayalakshmy K, Virmani M, Malik R, Rajalakshmi K, Kasthuri S. 2018. The Role of B vitamins in livestock nutrition. J Vet Med Res, 5(10), 1162.
48. Whaley SL, Hedgpeth VS, Britt JH. 1997. Evidence that injection of vitamin a before mating may improve embryo survival in gilts fed normal or high–energy diets. J Anim Sci, 75, 1071–1077.
49. Yao X, Zhang G, Guo Y, Ei–Samahy M, Wang S, Wan Y. 2017. Vitamin D receptor expression and potential role of vitamin D on cell proliferation and steroidogenesis in goat ovarian granulosa cells. Theriogenology, 102, 162–173.
50. Zohara BF, Azizunnesa R, Islam MF, Alam MGS, Bari FY. 2014 Comparison of estrus synchronization by PGF2α and progestagen sponge with PMSG in indigenous ewes in Bangladesh. Int J Vet Sci Res, 1, 27–37.