Menopozal Dönemdeki Kadınlarda Cinsel Disfonksiyonu Tedavi Etmek İçin Maca (Lepidium Meyenii) Kullanımı: Sistematik Derleme

Year 2023, Volume: 6 Issue: 3, 215 - 222, 29.12.2023

Belma Toptaş Acar Emine Gercek Oter

https://doi.org/10.54189/hbd.1275435

Abstract

Giriş: Dünyada ve ülkemizde yaşlı nüfusun artması ile kadınların menopoz sonrası yaşadıkları dönem uzamakta ve kadınlar daha fazla menopozal semptomlara maruz kalmaktadırlar. Maca turpgiller familyasına aittir ve Peru’da yetişmektedir. Maca bitkisi kadın cinsel disfonksiyonu tedavi etmek için kullanılır. Bu sistematik derleme, maca'nın menopoz dönemindeki cinsel disfonksiyonun tedavisindeki etkilerini belirlemeyi amaçladı.
Yöntem: Web of Science, PubMed, Scopus, Cochrane ve EBSCOhost veri tabanlarında lepidium meyenii, maca, lepidium meyenii ve sexual dysfunction, lepidium meyenii ve menopause, maca ve sexual dysfunction, maca ve menopause anahtar kelimeleri taranarak 2000-2022 yıllarında İngilizce olarak yayınlanan randomize kontrollü çalışmalar ve yarı-deneysel çalışmalar incelendi.
Bulgular: Toplam 85 katılımcıyı içeren 3 çalışma incelendi. Bir çalışma, maca'nın cinsel istek üzerinde hiçbir etkisi olmadığını gösterdi. Ancak başka bir araştırma cinsel istekte etkili olduğunu ortaya koydu. Maca'nın ayrıca başka bir çalışmada uyarılma ve orgazmı iyileştirdiği bildirildi.
Sonuç: Maca kullanımının cinsel fonksiyon bozukluklarında etkili olduğu çalışmalar olsa da; bu bitkinin ne kadar süre kullanılması gerektiği, hangi dozda verilebileceği, uzun vadedeki sonuçlarının neler olacağı konusunda yeterli veri bulunmamaktadır.

Keywords

Lepidium Meyenii, Maca, Menopoz, Cinsel Disfonksiyon, Kadın

Using Maca (Lepidium Meyenii) to Treat Sexual Dysfunction in Menopausal Women: A Systematic Review

Abstract

Background: With an increase in life expectancy and elderly population in the world, women experience a longer postmenopausal period and more menopausal symptoms. Maca belongs to the Cruciferous family and is cultivated in Peru. Maca plant is used to treat female sexual dysfunction. This systematic review aimed to determine the effects of maca on the treatment of sexual dysfunction during menopause.
Methods: Key words lepidium meyenii, maca, lepidium meyenii and sexual dysfunction, lepidium meyenii and menopause, maca and sexual dysfunction, maca and menopause were searched in databases Web of Science, PubMed, Scopus, Cochrane and EBSCOhost and randomized controlled studies and quasi-experimental studies published in the English language between 2000 and 2022 were reviewed.
Results: Three studies involving a total of 85 participants were reviewed. One study showed no effect of maca on sexual desire. However, another study revealed that it was effective in sexual desire. Maca was also reported to improve arousal and orgasm in another study.
Conclusion: Although there are studies that the use of maca is effective in sexual dysfunctions; there is not enough data on how long this plant should be used, at what dose it can be given, and what the long-term results will be.

Keywords

Lepidium Meyenii, Maca, Menopause, Sexual Dysfunction, Woman

References

• Aslan Demirtaş, F. A., Fırat, B., Sahin, N. (2022). Menopoz ve cinsel yaşam: Sistematik derleme. Androloji Bülteni (Andrology Bullettin), 24(2), 155-162.
• Baber, R., Panay, N., Fenton, A. (2016). IMS Recommendations on women's midlife health and menopause hormone therapy (MHT), Climacteric, 19 (2), 109- 150.
• Beharry, S., Heinrich, M. (2018). Is the hype around the reproductive health claims of maca (Lepidium meyenii Walp.) justified?. Journal of Ethnopharmacology, 211, 126-170. doi:10.1016/j.jep.2017.08.003.
• Bozkurt, Ö. D., Sevil, Ü. (2016). Menopoz ve cinsel yaşam. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 3(4), 497-503.
• Brooks, N. A., Wilcox, G., Walker, K. Z., Ashton, J. F., Cox, M. B., Stojanovska, L. (2008). Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content. Menopause, 15(6), 1157-1162.
• Brotto, L. A. (2017). Evidence-based treatments for low sexual desire in women. Frontiers in Neuroendocrinology, 45, 11-17. doi:10.1016/j.yfrne.2017.02.001.
• Centre for Reviews and Dissemination, University of York. (2008). Systematic Reviews CRD’s guidance for undertaking reviews in health care https://www.york.ac.uk/media/crd/Systematic_Reviews.pdf
• Dording, C. M., Fisher, L., Papakostas, G., Farabaugh, A., Sonawalla, S., Fava, M., Mischoulon, D. (2008). A double‐blind, randomized, pilot dose‐finding study of maca root (L. meyenii) for the management of SSRI‐induced sexual dysfunction. CNS Neuroscience & Therapeutics, 14(3), 182-191. doi:10.1111/j.1755-5949.2008.00052.x.
• Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-Based Complementary and Alternative Medicine, 1-9. doi:10.1155/2015/949036.
• Dos Reis, B. F., Rolim Lima, S. M., Silva, G. M. D., Postigo, S., Francisco, A. M. C., Barbosa, L. C. R., Brunet Filho, O. (2018). The effects of Lepidium meyenii Walp (Peruvian maca) on the sexual function of postmenopausal women. Menopause (New York, N.Y.). 25(12) (2018) 1518. doi:10.1097/GME.0000000000001251.
• Eftekhar, T., Dashti, M., Shariat, M., Haghollahi, F., Raisi, F., Ghahghaei-Nezamabadi, A. (2016). Female sexual function during the menopausal transition in a group of Iranian women. Journal of Family & Reproductive Health, 10(2), 52.
• Engin, B., Aydın Kartal, Y. (2020). Menopozal semptomlar ile baş etmede kullanılan tamamlayıcı ve alternatif tedavi yaklaşımları. Journal of Health Professionals Research, 2(2), 80-87.
• Erbil, N. (2018). Attitudes towards menopause and depression, body image of women during menopause. Alexandria Journal of Medicine, 54(39), 241-246. doi:10.1016/j.ajme.2017.05.012.
• Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.2 (updated February 2021). Cochrane, 2021, https://training.cochrane.org/handbook
• Kömürcü, N., İşbilen, A. (2011). Adaptation of women to sexual life during the postmenopausal period/Postmenopozal dönemde kadınların cinsel yaşama uyumu. Turkish Journal of Urology, 37(4), 326-331.
• Liu, P., Yuan, Y., Liu, M., Wang, Y., Li, X., Yang, M., Yao, C. (2015). Factors associated with menopausal symptoms among middle-aged registered nurses in Beijing. Gynecological Endocrinology, 31(2), 119-124. doi:10.3109/09513590.2014.971237.
• Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D, Moher, D. (2021).
• The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Systematic reviews, 10(1), 1-11.
• Rowland, D. L., Tai, W. (2003). A review of plant-derived and herbal approaches to the treatment of sexual dysfunctions. Journal of Sex &Marital Therapy, 29(3), 185-205.
• Royal College of Obstetrıcs and Gynecology. (2022). Menopause -a life stage. https://www.rcog.org.uk/en/patients/menopause/menopause---a-life-stage
• Ryan, R. (2013). Cochrane Consumers and Communication Review Group. Cochrane consumers and communication review group: data synthesis and analysis, Cochrane consumers and communication review group. 1–5.
• Shin, B. C., Lee, M. S., Yang, E. J., Lim, H. S., Ernst, E. (2010). Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complementary and Alternative Medicine, 10(1), 1-6.
• Snilstveit, B., Oliver, S., Vojtkova, M. (2012). Narrative approaches to systematic review and synthesis of evidence for international development policy and practice. Journal of Development Effectiveness, 4(3), 409-429. doi:10.1080/19439342.2012.710641.
• Stojanovska, L., Law, C., Lai, B., Chung, T., Nelson, K., Day, S., Haines, C. (2015). Maca reduces blood pressure and depression, in a pilot study in postmenopausal women. Climacteric, 18(1), 69-78. doi:10.3109/13697137.2014.929649
• Tezce, M.A., Beydağ, K.D. (2021). Menopausal perspective and sexual quality of life of women in menopause menopozdaki kadınların menopoza bakış açısı ve cinsel yaşam kalitesi. Sağlık ve Toplum 31 (1), 175-186.
• The American College of Obstetricians and Gynecologists. (2020). The Menopause Years. https://www.acog.org/womens-health/faqs/the-menopause-years
• Tufanaru, C., Munn, Z., Aromataris, E., Campbell, J., Hopp, L. (2017). Systematic reviews of effectiveness. Joanna Briggs Institute Reviewer’s Manual. Adelaide: Joanna Briggs Institute.
• Turkey Population and Health Survey. (2018). http://www.sck.gov.tr/wp-content/uploads/2020/08/TNSA2018_ana_Rapor.pdf
• Ünsal Atan, Ş., Yiğitoğlu, S. (2015). Menopozda semptom yönetimi ile ilgili kanıta dayalı uygulamalar. Uluslararası Hakemli Kadın Hastalıkları ve Anne Çocuk Sağlığı Dergisi, 3, 35-59.