Diyabetin Kronik Böbrek Hastalığını Gelişmesi ve Tedavisine Etkisi

Year 2011, Volume: 08 Issue: 1, 11 - 17, 30.06.2011

Feray Gökdo⁄an

Abstract

Diyabetes mellitus, diyaliz ya da transplantasyon gerektiren

son dönem böbrek hastal›¤›n›n bafll›ca nedenini ve yeni

vakalar›n %44’ünü oluflturmaktad›r. Diyabetli say›s›ndaki

art›fl ve toplumun yafllanmas›yla birlikte Son Dönem

Böbrek Hastal›¤› vakalar›n›n say›s› da artmaya devam etmektedir.

Diyabetik nefropati; proteinüri, hipertansiyon ve

ilerleyici böbrek yetmezli¤inin birlikte görüldü¤ü klinik bir

sendromdur. Diyabetik nefropatinin belirleyicileri olarak ailesel

ve genetik faktörler, diyabetin süresi, hiperglisemi,

proteinüri, hipertansiyon, hiperlipidemi, diyet ve sigara içme

büyük öneme sahip faktörlerdir. Bu makalede diyabetlilerde

s›k› bir metabolik kontrol ile sistemik ve glomerul hipertansiyonun

kontrolü, diyette protein k›s›tlamas›yla böbrek

fonksiyonlar›n›n korunup, diyabetik nefropatinin gelifliminin

geciktirilebilece¤i üzerinde durulmaktad›r.

Keywords

Diyabetik nefropati, Proteinüri, Korunma

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