Yetı̇şkı̇nlerde Ender Görülen Servı̇kal Rabdomı̇yosarkom Vakası

Year 2025, Volume: 7 Issue: 3, 476 - 481, 13.10.2025

Celal Akdemir , Halil İbrahim Yıldız , Mücahit Furkan Balcı , Özgür Erdoğan , Duygu Ayaz , Esra Canan Kelten Talu , Muzaffer Sancı

https://doi.org/10.52827/hititmedj.1683368

Abstract

Servikal embriyonel rabdomiyosarkom, kadın genital sistemindeki tüm servikal neoplazmların %1’inden azını oluşturan nadir görülen mezenkimal kaynaklı solid bir tümördür. Bu tümörün tedavisine yönelik standartlaştırılmış bir protokol bulunmamaktadır ve mevcut literatür büyük ölçüde olgu sunumları ve olgu serilerinden oluşmaktadır. Literatürde tanımlanan tedavi seçenekleri, fertilite koruyucu konservatif yaklaşımlardan, kemoterapi ve radyoterapi ile kombine edilen radikal cerrahiye kadar geniş bir yelpazeye yayılmaktadır. Cerrahi, kemoterapi ve radyoterapiyi içeren kombine tedavi yaklaşımının hastalığın seyrinde daha iyi sonuçlar sağladığı düşünülmektedir.
Bu yazıda, servikste polipoid bir kitle ile başvuran 45 yaşında kadın hastada görülen bir servikal embriyonel rabdomiyosarkom olgusunu sunmaktayız. Yapılan histopatolojik ve immünohistokimyasal incelemeler, servikste lokalize olan kitlenin servikal kökenli olduğunu ve embriyonel rabdomiyosarkom ile uyumlu olduğunu doğrulamıştır. Hastaya total abdominal histerektomi uygulanmasının ardından adjuvan kemoradyoterapi kombinasyon tedavisi önerilmiş, tedavi ardından hasta 23 aydır hastalıksız izlenimine devam etmektedir.

Keywords

Serviks Kanseri , Rabdomyosarkom , Mezenkimal Tümör

A Rare Case of Cervical Rhabdomyosarcoma in Adults

Abstract

Cervical embryonal rhabdomyosarcoma is a rare mesenchymal solid tumor that accounts for less than 1% of all cervical neoplasms in the female genital system. There is no standardized protocol for the treatment of cervical embryonal rhabdomyosarcoma, and the literature primarily consists of case reports and series. Treatment options described in the literature range from conservative, fertility-preserving approaches to radical surgery in combination with chemotherapy and radiotherapy. A combined approach involving surgery, chemotherapy, and radiotherapy is believed to yield better outcomes for the disease. In this article, we present a case of cervical embryonal rhabdomyosarcoma in a 45-year-old female patient presenting with a polypoid cervical mass. Histopathological and immunohistochemical examination confirmed that the localized mass in the cervix was of cervical origin and consistent with embryonal rhabdomyosarcoma. Following total abdominal hysterectomy, the patient was administered a combination treatment of adjuvant chemoradiotherapy, and she has remained disease-free for a period of 23 months.

Keywords

Cervical Cancer , Rhabdomyosarcoma , Mesenchymal Tumor

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