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Yaşlı Bireylerde Ağırlıkla Düzeltilmiş Bel Çevresi İndeksi ile Depresif Semptomlar Arasındaki İlişki

Year 2025, Volume: 7 Issue: 3, 379 - 385, 13.10.2025
https://doi.org/10.52827/hititmedj.1702507

Abstract

Amaç: Depresyon, yaşlı bireylerde yaygın ve işlevselliği bozan bir durumdur. Depresyon riskini öngörebilecek basit ve invaziv olmayan belirteçlerin tanımlanması, erken müdahale açısından büyük önem taşır. Ağırlıkla Düzeltilmiş Bel Çevresi İndeksi (WWI), santral obezitenin yeni bir antropometrik göstergesi olup yaşlı bireylerde depresif semptomlarla ilişkili olabilir. Bu çalışmanın amacı, WWI ile depresif semptomlar arasındaki ilişkiyi 65 yaş ve üzeri bireylerde incelemektir.
Gereç ve Yöntem: Bu retrospektif kesitsel çalışmaya, geriatri polikliniğine başvuran 65 yaş ve üzeri 150 hasta dâhil edilmiştir. Sosyodemografik, fonksiyonel, bilişsel, beslenme durumu ve antropometrik veriler toplanmıştır. Depresif semptomlar, Yesevage Geriatrik Depresyon Ölçeği (GDÖ) kullanılarak değerlendirilmiş; GDÖ skoru ≥5 olanlar depresyon olarak kabul edilmiştir. WWI, bel çevresinin (cm) vücut ağırlığının (kg) kareköküne bölünmesiyle hesaplanmıştır. Depresif semptomlarla bağımsız olarak ilişkili faktörleri belirlemek için ikili lojistik regresyon analizi uygulanmıştır.
Bulgular: Katılımcıların 53’ünde (%35,3) depresif semptomlar tespit edilmiştir. Depresif semptomları olan hastaların WWI değerleri anlamlı olarak daha yüksekti (11,68 ± 0,73 vs. 11,28 ± 0,66, p<0,001). Nihai regresyon modelinde; kadın olmak (OR: 3,17; %95 GA: 1,21–8,32; p=0,019), daha düşük SMMSE skoru (OR: 0,84; %95 GA: 0,75–0,95; p=0,005), daha yüksek WWI (OR: 1,66; %95 GA: 0,91–3,02; p=0,097) ve daha düşük MNA-SF skoru (OR: 0,76; %95 GA: 0,60–0,97; p=0,027) depresif semptomlarla ilişkili bulundu.
Sonuç: Yüksek WWI, yaşlı bireylerde depresif semptomlarla ilişkili olabilir. WWI, depresyon riski yüksek bireyleri belirlemek için kullanılabilecek basit ve invaziv olmayan bir araç olabilir. Bu bulguların doğrulanması için ileriye dönük çalışmalara ihtiyaç vardır.

References

  • Maier A, Riedel-Heller SG, Pabst A, Luppa M. Risk factors and protective factors of depression in older people 65+. A systematic review. PLoS One 2021;16(5):e0251326.
  • Kim NH, Park Y, Kim NH, Kim SG. Weight-adjusted waist index reflects fat and muscle mass in the opposite direction in older adults. Age Ageing 2021;50(3):780-786.
  • Li M, Yu X, Zhang W, et al. The association between weight-adjusted-waist index and depression: Results from NHANES 2005-2018. J Affect Disord 2024;347:299-305.
  • Shen Y, Wu Y, Luo P, Fu M, Zhu K, Wang J. Association between weight-adjusted-waist index and depression in US adults: A cross-sectional study. J Affect Disord 2024;355:299-307.
  • Zeng P, Jiang C, Cao J, Li M, Lin F. Longitudinal relationship between weight-adjusted waist index and depressive symptoms in middle-aged and older Chinese adults: A prospective cohort study. J Affect Disord 2024;363:381-390.
  • Korycka-Bloch R, Balicki P, Guligowska A, Soltysik BK, Kostka T, Chrzastek Z. Weight-Adjusted Waist Index (WWI)—A Promising Anthropometric Indicator of Depressive Symptoms in Hospitalized Older Patients. Nutrients 2024;17(1).
  • Wang J, Wang Y, Li S, et al. Waist-to-weight index and cognitive impairment: Understanding the link through depression mediation in the NHANES. J Affect Disord 2024;365:313-320.
  • Arik G, Varan HD, Yavuz BB, et al. Validation of Katz index of independence in activities of daily living in Turkish older adults. Arch Gerontol Geriatr 2015;61(3):344-350.
  • Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of Illness in the Aged. The Index of ADL: A Standardized Measure of Biological and Psychosocial Function. JAMA 1963;185:914-919.
  • Isik EI, Yilmaz S, Uysal I, Basar S. Adaptation of the Lawton Instrumental Activities of Daily Living Scale to Turkish: Validity and Reliability Study. Ann Geriatr Med Res 2020;24(1):35-40.
  • Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9(3):179-186.
  • Molloy DW, Alemayehu E, Roberts R. Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. Am J Psychiatry 1991;148(1):102-105.
  • Rockwood K, Theou O. Using the Clinical Frailty Scale in Allocating Scarce Health Care Resources. Can Geriatr J 2020;23(3):210-215.
  • Aşık Z, Kılınç Ş, Kurşun Ö, Özen M. Validation of the Clinical Frailty Scale version 2.0 in Turkish older patients. Geriatr Gerontol Int 2022;22(9):730-735.
  • Guigoz Y, Lauque S, Vellas BJ. Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment. Clin Geriatr Med 2002;18(4):737-757.
  • Sarikaya D, Halil M, Kuyumcu ME, et al. Mini nutritional assessment test long and short form are valid screening tools in Turkish older adults. Arch Gerontol Geriatr 2015;61(1):56-60.
  • Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40(5):373-383.
  • Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17(1):37-49.
  • Durmaz B, Soysal P, Ellidokuz H, Isik AT. Validity and reliability of geriatric depression scale-15 (short form) in Turkish older adults. North Clin Istanb 2018;5(3):216-220.
  • Niu Y, Sun Y, Xie Y, Yu S. Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016. Front Public Health 2024;12:1461300.
  • Wang XL, Feng HL, Xu XZ, Liu J, Han X. Relationship between cognitive function and weight-adjusted waist index in people ≥60 years old in NHANES 2011-2014. Aging Clin Exp Res 2024;36(1):30.
  • Guo S, Qing G, Chen Q, Yang G. The relationship between weight-adjusted-waist index and suicidal ideation: evidence from NHANES. Eat Weight Disord 2024;29(1):37.
  • Hu C, Sun X, Li Z, et al. Multitrajectories of Frailty and Depression with Cognitive Function: Findings From the Health and Retirement Longitudinal Study. J Cachexia Sarcopenia Muscle 2025;16(2):e13795.
  • Cuijpers P, Smit F, Patel V, Dias A, Li J, Reynolds CF, 3rd. Prevention of depressive disorders in older adults: An overview. PsyCh J 2015;4(1):3-10.
  • Casey DA. Depression in Older Adults: A Treatable Medical Condition. Prim Care 2017;44(3):499-510.
  • Kok RM, Reynolds CF, 3rd. Management of Depression in Older Adults: A Review. JAMA 2017;317(20):2114-2122.
  • Weyerer S, Eifflaender-Gorfer S, Wiese B, et al. Incidence and predictors of depression in non-demented primary care attenders aged 75 years and older: results from a 3-year follow-up study. Age Ageing 2013;42(2):173-180.

Association Between Weight-Adjusted Waist Index and Depressive Symptoms in Older Adults

Year 2025, Volume: 7 Issue: 3, 379 - 385, 13.10.2025
https://doi.org/10.52827/hititmedj.1702507

Abstract

Objective: Depression is a common and disabling condition in older adults. Identifying simple, non-invasive predictors of depression risk is essential for early intervention. The Weight-Adjusted Waist Index (WWI), a novel anthropometric marker of central adiposity, may be associated with depressive symptoms in older populations. This study aims to investigate the association between WWI and depressive symptoms in adults aged 65 years and older.
Material and Methods: This retrospective cross-sectional study included 150 patients aged ≥65 years attending a geriatrics outpatient clinic. Sociodemographic, functional, cognitive, nutritional, and anthropometric data were collected. Depressive symptoms were assessed using the Yesevage Geriatric Depression Scale (GDS), with scores ≥5 indicating depression. WWI was calculated as waist circumference (cm) divided by the square root of weight (kg). Binary logistic regression analysis was performed to identify factors independently associated with depressive symptoms.
Results: Depressive symptoms were present in 53 participants (35.3%). Patients with depressive symptoms had significantly higher WWI values (11.68 ± 0.73 vs. 11.28 ± 0.66, p<0.001). In the final regression model, being women (OR: 3.17; 95% CI: 1.21–8.32; p=0.019), lower SMMSE score (OR: 0.84; 95% CI: 0.75–0.95; p=0.005), higher WWI (OR: 1.66; 95% CI: 0.91–3.02; p=0.097), and lower MNA-SF score (OR: 0.76; 95% CI: 0.60–0.97; p=0.027) were associated with depressive symptoms.
Conclusion: Higher WWI may be linked to depressive symptoms in older adults. WWI could serve as a simple, non-invasive tool to help identify individuals at increased risk of depression. Longitudinal studies are needed to confirm these findings.

Ethical Statement

Ethical approval was obtained from the Ankara Bilkent City Hospital clinical research ethics committee on 14.05.25 with the reference number of TABED 2-25-1219.

References

  • Maier A, Riedel-Heller SG, Pabst A, Luppa M. Risk factors and protective factors of depression in older people 65+. A systematic review. PLoS One 2021;16(5):e0251326.
  • Kim NH, Park Y, Kim NH, Kim SG. Weight-adjusted waist index reflects fat and muscle mass in the opposite direction in older adults. Age Ageing 2021;50(3):780-786.
  • Li M, Yu X, Zhang W, et al. The association between weight-adjusted-waist index and depression: Results from NHANES 2005-2018. J Affect Disord 2024;347:299-305.
  • Shen Y, Wu Y, Luo P, Fu M, Zhu K, Wang J. Association between weight-adjusted-waist index and depression in US adults: A cross-sectional study. J Affect Disord 2024;355:299-307.
  • Zeng P, Jiang C, Cao J, Li M, Lin F. Longitudinal relationship between weight-adjusted waist index and depressive symptoms in middle-aged and older Chinese adults: A prospective cohort study. J Affect Disord 2024;363:381-390.
  • Korycka-Bloch R, Balicki P, Guligowska A, Soltysik BK, Kostka T, Chrzastek Z. Weight-Adjusted Waist Index (WWI)—A Promising Anthropometric Indicator of Depressive Symptoms in Hospitalized Older Patients. Nutrients 2024;17(1).
  • Wang J, Wang Y, Li S, et al. Waist-to-weight index and cognitive impairment: Understanding the link through depression mediation in the NHANES. J Affect Disord 2024;365:313-320.
  • Arik G, Varan HD, Yavuz BB, et al. Validation of Katz index of independence in activities of daily living in Turkish older adults. Arch Gerontol Geriatr 2015;61(3):344-350.
  • Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of Illness in the Aged. The Index of ADL: A Standardized Measure of Biological and Psychosocial Function. JAMA 1963;185:914-919.
  • Isik EI, Yilmaz S, Uysal I, Basar S. Adaptation of the Lawton Instrumental Activities of Daily Living Scale to Turkish: Validity and Reliability Study. Ann Geriatr Med Res 2020;24(1):35-40.
  • Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9(3):179-186.
  • Molloy DW, Alemayehu E, Roberts R. Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. Am J Psychiatry 1991;148(1):102-105.
  • Rockwood K, Theou O. Using the Clinical Frailty Scale in Allocating Scarce Health Care Resources. Can Geriatr J 2020;23(3):210-215.
  • Aşık Z, Kılınç Ş, Kurşun Ö, Özen M. Validation of the Clinical Frailty Scale version 2.0 in Turkish older patients. Geriatr Gerontol Int 2022;22(9):730-735.
  • Guigoz Y, Lauque S, Vellas BJ. Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment. Clin Geriatr Med 2002;18(4):737-757.
  • Sarikaya D, Halil M, Kuyumcu ME, et al. Mini nutritional assessment test long and short form are valid screening tools in Turkish older adults. Arch Gerontol Geriatr 2015;61(1):56-60.
  • Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40(5):373-383.
  • Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17(1):37-49.
  • Durmaz B, Soysal P, Ellidokuz H, Isik AT. Validity and reliability of geriatric depression scale-15 (short form) in Turkish older adults. North Clin Istanb 2018;5(3):216-220.
  • Niu Y, Sun Y, Xie Y, Yu S. Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016. Front Public Health 2024;12:1461300.
  • Wang XL, Feng HL, Xu XZ, Liu J, Han X. Relationship between cognitive function and weight-adjusted waist index in people ≥60 years old in NHANES 2011-2014. Aging Clin Exp Res 2024;36(1):30.
  • Guo S, Qing G, Chen Q, Yang G. The relationship between weight-adjusted-waist index and suicidal ideation: evidence from NHANES. Eat Weight Disord 2024;29(1):37.
  • Hu C, Sun X, Li Z, et al. Multitrajectories of Frailty and Depression with Cognitive Function: Findings From the Health and Retirement Longitudinal Study. J Cachexia Sarcopenia Muscle 2025;16(2):e13795.
  • Cuijpers P, Smit F, Patel V, Dias A, Li J, Reynolds CF, 3rd. Prevention of depressive disorders in older adults: An overview. PsyCh J 2015;4(1):3-10.
  • Casey DA. Depression in Older Adults: A Treatable Medical Condition. Prim Care 2017;44(3):499-510.
  • Kok RM, Reynolds CF, 3rd. Management of Depression in Older Adults: A Review. JAMA 2017;317(20):2114-2122.
  • Weyerer S, Eifflaender-Gorfer S, Wiese B, et al. Incidence and predictors of depression in non-demented primary care attenders aged 75 years and older: results from a 3-year follow-up study. Age Ageing 2013;42(2):173-180.
There are 27 citations in total.

Details

Primary Language English
Subjects Geriatrics and Gerontology
Journal Section Research Articles
Authors

Ayşe Dikmeer 0000-0003-3016-8173

Suna Bürkük 0000-0001-7342-7097

Publication Date October 13, 2025
Submission Date May 20, 2025
Acceptance Date August 31, 2025
Published in Issue Year 2025 Volume: 7 Issue: 3

Cite

AMA Dikmeer A, Bürkük S. Association Between Weight-Adjusted Waist Index and Depressive Symptoms in Older Adults. Hitit Medical Journal. October 2025;7(3):379-385. doi:10.52827/hititmedj.1702507