The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria

Nazif Kolankaya; Atilla Atalay; Sevda Gokdeniz

The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria

Abstract

Kidd 1953 first observed that certain transplanted lymphomas of mice and rats were strongly suppressed by treatment with guinea pig serum, and Broome 1961 provided evidence that L-asparaginase in the serum is the antitumoral factor. The finding by Mashburn and Wriston 1964 that L-asparaginase derived from Escherichia coli has antitumor activity similar to that of guinea pig serum opened up the possibility of large scale production of the enzyme for ultimate clinical trial.

References

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4. Deangeli, L.C.; Pochiari, F.; Tanola, A.; Zurita, V.E.; Ciaranfi, E.; and Perin, A. 1970. Effect of L-asparaginase from Aspergillus terreus on ascites sarcoma in the rat. Nature (London) 225: 549
5. Heinemann, B.; Howard, A.J.; and Palocz, H.J., 1970. Influence of dissolvedoxygen levels on production of Lasparaginase and prodigiosin by Serratia marcescens. Appl.Miaobiol. 19:800
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7. Hill,J.M.; Loeb, E.; Maclellan, A; Khan, A.; Roberts,J.; Schields, W.F.; and Hill, N.O., 1969. Response to highly prufied L-asparaginase during therapy of acute leukemia. Cancer Res. 29:1574.
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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Nazif Kolankaya This is me

Atilla Atalay This is me

Sevda Gokdeniz This is me

Publication Date

May 1, 1975

Submission Date

-

Acceptance Date

-

Published in Issue

Year 1975 Number: 4

IZ

https://izlik.org/JA54LD99XY

Cite

RIS / Bibtex

APA

Kolankaya, N., Atalay, A., & Gokdeniz, S. (1975). The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria. Hacettepe Journal of Biology and Chemistry, 4, 17-23. https://izlik.org/JA54LD99XY

AMA

1.Kolankaya N, Atalay A, Gokdeniz S. The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria. HJBC. 1975;(4):17-23. https://izlik.org/JA54LD99XY

Chicago

Kolankaya, Nazif, Atilla Atalay, and Sevda Gokdeniz. 1975. “The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria”. Hacettepe Journal of Biology and Chemistry, nos. 4: 17-23. https://izlik.org/JA54LD99XY.

EndNote

Kolankaya N, Atalay A, Gokdeniz S (May 1, 1975) The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria. Hacettepe Journal of Biology and Chemistry 4 17–23.

IEEE

[1]N. Kolankaya, A. Atalay, and S. Gokdeniz, “The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria”, HJBC, no. 4, pp. 17–23, May 1975, [Online]. Available: https://izlik.org/JA54LD99XY

ISNAD

Kolankaya, Nazif - Atalay, Atilla - Gokdeniz, Sevda. “The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria”. Hacettepe Journal of Biology and Chemistry. 4 (May 1, 1975): 17-23. https://izlik.org/JA54LD99XY.

JAMA

1.Kolankaya N, Atalay A, Gokdeniz S. The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria. HJBC. 1975;:17–23.

MLA

Kolankaya, Nazif, et al. “The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria”. Hacettepe Journal of Biology and Chemistry, no. 4, May 1975, pp. 17-23, https://izlik.org/JA54LD99XY.

Vancouver

1.Nazif Kolankaya, Atilla Atalay, Sevda Gokdeniz. The Isolation of L-Asparaginase and L-Serine Dehydratase from Bacteria. HJBC [Internet]. 1975 May 1;(4):17-23. Available from: https://izlik.org/JA54LD99XY