Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients

Muhammed Emin Düz; Aydın Balcı

Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients

Abstract

Asthma is a chronic disease characterized by the presence of inflammatory agents in the airways, and diagnosis and treatment are based on clinical questioning, physical examination, laboratory results, and spirometric analysis. This study investigated the effect of asthma alone on routine laboratory parameters in adults and whether an idea about the course of the disease can be obtained using these parameters. Two hundred and fourteen patients with known asthma history, diagnosed, and treated according to guidelines, were included in our study. Among all patients and between gender-specific groups, total cholesterol (CHOL), HDL, LDL, VLDL, triglyceride (TG), albumin, total protein (TP), lactate dehydrogenase (LDH), glucose, urea, creatinine, C reactive protein (CRP), FeNO, SII, INR, and complete blood count value parameters of the patients were analyzed. When we consider all asthma patients, we found that the mean glucose, LDH, CRP, TG, FeNO, and INR values outpaced the upper limit of the reference range. In contrast, the mean HDL value was below the reference range for all patients. In addition, our study found a significant correlation between triglyceride levels within the biochemical parameters with FeNO and SII). Finally, when we compared the mean values of gender-specific groups, we found a statistically significant difference between VLDL, HDL, TG, CRP, FeNO, creatinine, lymphocyte, eosinophile, basophile, and hemoglobin. CRP, LDH, TG, FeNO, SII, and INR levels may help clinicians in adult patients with stable asthma. In addition, differences depending on gender could be observed in the biochemical parameters of asthma patients.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Muhammed Emin Düz This is me
0000-0002-1837-6415
Türkiye

Aydın Balcı This is me
0000-0002-6723-2418
Türkiye

Publication Date

April 24, 2022

Submission Date

October 9, 2021

Acceptance Date

February 16, 2022

Published in Issue

Year 2022 Volume: 2 Number: 2

IZ

https://izlik.org/JA42AT75BA

Cite

RIS / Bibtex

Vancouver

1.Muhammed Emin Düz, Aydın Balcı. Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients. Health Sci. Q. [Internet]. 2022 Apr. 1;2(2):101-9. Available from: https://izlik.org/JA42AT75BA