Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients

Muhammed Emin Düz; Aydın Balcı

Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients

Abstract

Asthma is a chronic disease characterized by the presence of inflammatory agents in the airways, and diagnosis and treatment are based on clinical questioning, physical examination, laboratory results, and spirometric analysis. This study investigated the effect of asthma alone on routine laboratory parameters in adults and whether an idea about the course of the disease can be obtained using these parameters. Two hundred and fourteen patients with known asthma history, diagnosed, and treated according to guidelines, were included in our study. Among all patients and between gender-specific groups, total cholesterol (CHOL), HDL, LDL, VLDL, triglyceride (TG), albumin, total protein (TP), lactate dehydrogenase (LDH), glucose, urea, creatinine, C reactive protein (CRP), FeNO, SII, INR, and complete blood count value parameters of the patients were analyzed. When we consider all asthma patients, we found that the mean glucose, LDH, CRP, TG, FeNO, and INR values outpaced the upper limit of the reference range. In contrast, the mean HDL value was below the reference range for all patients. In addition, our study found a significant correlation between triglyceride levels within the biochemical parameters with FeNO and SII). Finally, when we compared the mean values of gender-specific groups, we found a statistically significant difference between VLDL, HDL, TG, CRP, FeNO, creatinine, lymphocyte, eosinophile, basophile, and hemoglobin. CRP, LDH, TG, FeNO, SII, and INR levels may help clinicians in adult patients with stable asthma. In addition, differences depending on gender could be observed in the biochemical parameters of asthma patients.

Keywords

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Muhammed Emin Düz Bu kişi benim
0000-0002-1837-6415
Türkiye

Aydın Balcı Bu kişi benim
0000-0002-6723-2418
Türkiye

Yayımlanma Tarihi

24 Nisan 2022

Gönderilme Tarihi

9 Ekim 2021

Kabul Tarihi

16 Şubat 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 2 Sayı: 2

IZ

https://izlik.org/JA42AT75BA

Kaynak Göster

RIS / Bibtex

Vancouver

1.Muhammed Emin Düz, Aydın Balcı. Assessment of plasma lipid parameters, exhaled nitric oxide fraction, and systemic immune-inflammation index on stable asthma patients. Health Sci. Q. [Internet]. 01 Nisan 2022;2(2):101-9. Erişim adresi: https://izlik.org/JA42AT75BA