A new adjusted Bayesian method in Cox regression model with covariate subject to measurement error

Abstract

An important bias can occur when estimating coefficients by maximizing the known partial likelihood function in the Cox regression model with the measurement error covariate. We focus here on Bayesian methods in order to adjust measurement error and aim to propose an adjusting Bayesian method. Constructing simulation studies using Markov Chain Monte Carlo simulation techniques to investigate the performance of models. We compare the proposed method with the existing method that used partial likelihood function, Bayesian Cox regression model ignoring measurement error, the adjusted Bayesian Cox regression model that exists in the literature by a simulation study which consists of different sample sizes, censoring rates, reliability levels, and regression coefficients. Simulation studies indicate that the proposed method outperformed others given some scenarios. A real data set is analyzed for an illustration of the findings.

Keywords

• Cox regression model
• Bayesian analysis
• polygonal function prior
• measurement error

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