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Prevention of Medication Errors in Pediatric Patients

Year 2010, Volume: 17 Issue: 1, 63 - 71, 01.03.2010

Abstract

Children are particularly sensitive group that should be considered in all efforts which aim to prevent the medication errors and to provide safe of medication administrations. The increased need for calculations, dilutions and manipulation of pediatric medicines, together with a need to dose on an individual patient basis using age, body weight and/or surface area, means that they are more prone to medication errors at each stage of the medicines management process. Consequently, the risk for being harmed due to medication errors in pediatrics may increase. Dose calculation errors are the most observed medication error type in pediatric and neonatal units. This type of error may occur because of nonexistence of commercial forms of medicine for children, packaging, labeling, prescription system, working conditions of profession or special characteristics of the professionals. Accordingly, when taking measures for minimizing the medication errors, all these effects and processes should be taken in to consideration. To decrease the medication administration errors, recommended precautions and practices for nurses included careful medication calculations, double-check of medications, informing the child and care giver about pediatric medication, reporting the medication errors, and arranging the working conditions to diminish the distractions. In this article, the most common medication administration errors and recommendations to prevent medication errors in pediatric patients were discussed.

References

  • Prot S, Fontan JE, Alberti C, Bourdon E, Farnoux C, Macher MA. Drug administration errors and their determinants in pediatric inpatients. Int J Qual Health Care 2005; 17: 381-9.
  • Wong IC, Ghaleb MA, Franklin BD, Barber N. Incidence and nature of dosing errors in pediatric medication a systematic review. Drug Safety 2004; 27: 661-70.
  • Institute of Medicine (IOM). To Err Is Human: Bulding a Safer Health System. In: Kohn LT, Corrigan JM, Donaldson MS, eds. Washington DC: National Academy Press; 2000. p.1-48.
  • American Academy of Pediatrics (AAP). Prevention of medication errors in the pediatric inpatient setting. Pediatrics 2003; 112: 431-36.
  • Institute of Medicine (IOM) Preventing Medication Errors: Quality Chasm Series, Committee on Identifying and Preventing Medication Errors. In: Aspden P, Wolcott J, Bootman JL, Cronenwett LR, eds. Washington DC: Academy Press; 2006. p.105-142.
  • Cote CJ, Notterman DA, Karl H, Weinberg JA, McCloskey C. Adverse sedation events in pediatrics: A critical incident analysis of contributing factors. Pediatrics 2000; 105: 805-14.
  • Slonin AD, LaFleur BJ, Ahmed W, Joseph JG. Hospital reported errors in children. Pediatrics 2003; 111: 617-21.
  • Lehmann CU, Kin GR. Prevention of medication errors. Clin Perinatol 2005; 32: 107-32.
  • O'shea E. Factors contributing to medication error: A literature review. Journal of Clinical Nursing 1999; 8: 496-503.
  • Ferranti J, Horvath M, Cozart H, Whitehurst J, Eckstrand J. Reevaluating the safety profile of pediatrics: A comparison of computerized adverse drug even surveillance and voluntary reporting in the pediatric environment. Pediatrics 2008; 121: 1201-7.
  • Engum SA, Breckler FD. An evaluation of mediacation errors - the pediatric surgical service experience. Journal of Pediatric Surgery 2008; 43: 348-52.
  • Stratton KM, Blegen MA, Pepper G, Vaughn T. Reporting of medication errors by pediatric nurses. J Ped Nur 2004; 19: 385-92.
  • Alparslan Ö, Erdemir F. Pediatrik servislerinde kullanılan antibiyotiklerin sulandırılması, saklanması ve hastaya verilmesi konusunda hemşirelerin bilgi ve uygulamalarının belirlenmesi. Cumhuriyet Üniversitesi Dergisi Hemşirelik Yüksekokulu Dergisi 1997; 1(1): 41-52.
  • Kaushal R, Bates DW, Landrigan C, McKenna KJ, Clapp MD, Federico F. Medication errors and adverse drug events in pediatric inpatients. Journal of the American Medical Association 2001; 285: 2114-20.
  • Fijin R, Van den Bernt P, Chow M, DeBlacey C, DeJong-Van den Berg L, Brouwers J. Hospital prescribing errors: Epidemiological assessment of predictors. British Journal of Clinical Pharmacology 2002; 53: 326-31.
  • Ferner RE, Langford NJ, Anton C, Hutchings A, Bateman DN, Routledge PA. Random and systematic medication errors in routine clinical practice: A multicentre study of infusions, using acetylcysteine as an example. Br J Clin Pharmacol 2001; 52: 573-7.
  • Hronek C, Bleich MR. The less-than-perfect medication system: A systems approach to improvement. J Nurs Care Qual 2002; 16: 17-22.
  • Tang FI, Sheu SJ, Yu S, Wei IL, Chen CH. Nurses relate the contributing factors involved in medication errors. J Clin Nurs 2007; 16: 447-57.
  • Ross LM, Wallace J, Paton JY. Medication errors in a paediatric teaching hospital in the UK: Five years operational experience. Arch Dis Child 2000; 83: 492-7.
  • Frey B, Buettiker EV, Hug EM, Waldvogel K, Gessler EP, Ghelfi ED. Does critical encident reporting contribute to medication error prevention. Eur J Pediatr 2002; 161: 594-9.
  • Otero P, Leyton A, Mariani G, Ceriani J. Medication errors in pediatric inpatients: Prevalence and results of a prevention program. Pediatrics 2008; 22: 737-43.
  • Hicks RW, Becker SC, Cousins DD. Harmful medication errors in children: A 5-year analysis of data from the USP's MEDMARXR Program. Journal of Pediatric Nursing 2006; 21: 290-98.
  • Ghaleb M, Barber N, Franklin B, Yeung V, Khaki Z, Wong I. Systematic review of medication errors in pediatric patients. Annals of Pharmacotherapy 2006; 40: 1766-76.
  • Payne C, Smith C, Newkirk L, Hicks R. Pediatric medication errors in the postanesthesia care unit: Analysis of MEDMARX data. AORN Journal 2007; 85: 731-40.
  • Sandlin D. Pediatric medication error prevention. Journal of Peri Anesthesia Nursing 2008; 23: 279-81.
  • Lefrak L. Moving towards safer practice: Reducing medication errors in neonatal care. Journal of Perinatal and Neonatal Nurses 2002; 16: 73−84.
  • Westbrook JI, Woods A, Rob MI, Dunsmuir WT, Day RO. Association of interruptions with an increased risk and severity of medication administration errors. Arch Intern Med 2010; 170: 683-90.
  • Fernald D. Event reporting to a primary care patient safety reporting system, a report from the ASIPS Collaborative. Ann Fam Med 2004; 2: 327-32.
  • Blendon RJ, Desroches CM, Brodie M. Views of practising physicians and the public on medical errors. N Engl J Med 2002; 347: 1993-40.
  • Tutle D, Holloway R, Daird T, Sheehan B, Skelton W. Electronic reporting to improve patient safety. Qualty & Safely in Health Care 2004; 13: 281-86.
  • Zhan C, Hicks RW, Blanchette CM, Keyes MA, Cousins DD. Potential benefits and problems with computerized prescriber order entry: Analysis of a voluntary medication error-reporting database. Am J Health-Syst Pharm 2006; 63: 353-58.
  • Ray MD, Aldrich LT, Lew PJ. Experience with an automated point of use unit dose drug distribution system. Hospital Pharmacy 1995; 30: 18,20-23,27-30.
  • Borel JM, Rascati KL. Effect of an automated nursing unit based drug dispensing device on medication errors. American Journal of Health-System Pharmacy 1995; 52: 1875-187.
  • Sowan AK, Gaffoor MI, Soeken K, Johantgen ME, Vaidya, VU. Impact of computerized orders for pediatric continuous drug infusions on detecting infusion pump programming errors: A simulated study. Journal of Pediatric Nursing 2010; 25: 108-18.
  • Anderson S, Wittwer W. Using barcode point-of-care technology for patient safety. J Health Care Qual 2004; 26: 5-11.
  • Paoletti RD, Suess TM, Lesko MG, Feroli AA, Kennel JA, Mahler JM, et al. Using barcode technology and medication observation methodology for safer medication administration. Am J Health Syst Pharm 2007; 64: 536-43.
  • Savaşer S, Çimen S, Yıldırım S. Flakon şeklindeki antibiyotiklerde kuru toz hacminin uygulanacak doz üzerine etkisi. İ.Ü.F.N. Hem. Dergisi 2008; 16: 7-15.
  • Davidhizar R, Lonser G. Strategies to decrease medication errors. Health Care Manager 2003; 22: 211-18.
  • Uzun Ş, Arslan F. İlaç uygulama hataları. Türkiye Klinikleri J Med Sci 2008; 28: 217-22.
  • The Joint Commission. Preventing pediatric medication errors. Sentinel Event Alert. 2008; April. URL: http://www.jointcommission.org/sentinelevents/sentinel eventalert/sea_39.htm. May 4, 2009.
  • National Coordinating Council for Medication Error Reporting and Prevention. Recommendations to enhance accuracy of administration of medications. 1999; June. URL: http://www.nccmerp.org/council/ council1999-06-29.html. March 29, 2009.
  • Schneider MP, Cotting J, Pannatier A. Evaluation of nurses' errors associated in the preparation and administration of medication in a pediatric intensive care unit. Pharm World Sci 1998; 20: 178-82.

Pediatrik Hastalarda İlaç Uygulama Hatalarının Önlenmesi

Year 2010, Volume: 17 Issue: 1, 63 - 71, 01.03.2010

Abstract

İlaç uygulama hatalarının önlenmeye ve güvenli ilaç uygulamalarını sağlamaya yönelik çalışmalarda çocuklar özel dikkat gösterilmesi gereken hasta grubunu oluşturmaktadır. Pediatrik ilaçlarda gereken dozun çocuğun yaşına, vücut ağırlığına ve/ veya vücut yüzey alanına göre hesaplanması, ilaçların sulandırılması, sulandırılan ilaçtan istenen dozu elde etmek için hesaplamaların gerekmesi ilaç uygulama süreçlerinin her bir evresinde hata olasılığını artırmaktadır. Dolayısıyla, çocuğun ilaç hatalarına bağlı zarar görme riski artmaktadır. Pediatri ve yenidoğan ünitelerinde en sık görülen ilaç uygulama hatası tipi doz hesaplama hatalarıdır. Bu hatalar ilaçların çocuklara özel ticari formlarının bulunmamasından, ürünün paketleme, etiketleme ve adlandırma sisteminden, reçeteleme/ istemleme ve istem iletimi sistemlerinden, mesleğin çalışma koşullarından, profesyonel uygulamanın özelliklerinden kaynaklanabilir. Dolayısı ile ilaç hatalarının en aza indirilmesi için önlemler alınırken tüm bu etkenler ve uygulama süreçleri göz önünde bulundurulmalıdır. İlaç uygulama hatalarının azaltılmasında hemşirelere yönelik önerilen önlem ve uygulamalar arasında dikkatli doz hesaplamaları, çift kontrol, çocuk ve ailenin bilgilendirilmesi, hataların bildirimi, çalışma koşullarının düzenlenerek dikkat eksikliğine bağlı hataların azaltılması yer almaktadır. Bu makalede, çocuk hastalarda sık görülen ilaç uygulama hataları ve bu hataların önlenmesine yönelik öneriler tartışılmaktadır.

References

  • Prot S, Fontan JE, Alberti C, Bourdon E, Farnoux C, Macher MA. Drug administration errors and their determinants in pediatric inpatients. Int J Qual Health Care 2005; 17: 381-9.
  • Wong IC, Ghaleb MA, Franklin BD, Barber N. Incidence and nature of dosing errors in pediatric medication a systematic review. Drug Safety 2004; 27: 661-70.
  • Institute of Medicine (IOM). To Err Is Human: Bulding a Safer Health System. In: Kohn LT, Corrigan JM, Donaldson MS, eds. Washington DC: National Academy Press; 2000. p.1-48.
  • American Academy of Pediatrics (AAP). Prevention of medication errors in the pediatric inpatient setting. Pediatrics 2003; 112: 431-36.
  • Institute of Medicine (IOM) Preventing Medication Errors: Quality Chasm Series, Committee on Identifying and Preventing Medication Errors. In: Aspden P, Wolcott J, Bootman JL, Cronenwett LR, eds. Washington DC: Academy Press; 2006. p.105-142.
  • Cote CJ, Notterman DA, Karl H, Weinberg JA, McCloskey C. Adverse sedation events in pediatrics: A critical incident analysis of contributing factors. Pediatrics 2000; 105: 805-14.
  • Slonin AD, LaFleur BJ, Ahmed W, Joseph JG. Hospital reported errors in children. Pediatrics 2003; 111: 617-21.
  • Lehmann CU, Kin GR. Prevention of medication errors. Clin Perinatol 2005; 32: 107-32.
  • O'shea E. Factors contributing to medication error: A literature review. Journal of Clinical Nursing 1999; 8: 496-503.
  • Ferranti J, Horvath M, Cozart H, Whitehurst J, Eckstrand J. Reevaluating the safety profile of pediatrics: A comparison of computerized adverse drug even surveillance and voluntary reporting in the pediatric environment. Pediatrics 2008; 121: 1201-7.
  • Engum SA, Breckler FD. An evaluation of mediacation errors - the pediatric surgical service experience. Journal of Pediatric Surgery 2008; 43: 348-52.
  • Stratton KM, Blegen MA, Pepper G, Vaughn T. Reporting of medication errors by pediatric nurses. J Ped Nur 2004; 19: 385-92.
  • Alparslan Ö, Erdemir F. Pediatrik servislerinde kullanılan antibiyotiklerin sulandırılması, saklanması ve hastaya verilmesi konusunda hemşirelerin bilgi ve uygulamalarının belirlenmesi. Cumhuriyet Üniversitesi Dergisi Hemşirelik Yüksekokulu Dergisi 1997; 1(1): 41-52.
  • Kaushal R, Bates DW, Landrigan C, McKenna KJ, Clapp MD, Federico F. Medication errors and adverse drug events in pediatric inpatients. Journal of the American Medical Association 2001; 285: 2114-20.
  • Fijin R, Van den Bernt P, Chow M, DeBlacey C, DeJong-Van den Berg L, Brouwers J. Hospital prescribing errors: Epidemiological assessment of predictors. British Journal of Clinical Pharmacology 2002; 53: 326-31.
  • Ferner RE, Langford NJ, Anton C, Hutchings A, Bateman DN, Routledge PA. Random and systematic medication errors in routine clinical practice: A multicentre study of infusions, using acetylcysteine as an example. Br J Clin Pharmacol 2001; 52: 573-7.
  • Hronek C, Bleich MR. The less-than-perfect medication system: A systems approach to improvement. J Nurs Care Qual 2002; 16: 17-22.
  • Tang FI, Sheu SJ, Yu S, Wei IL, Chen CH. Nurses relate the contributing factors involved in medication errors. J Clin Nurs 2007; 16: 447-57.
  • Ross LM, Wallace J, Paton JY. Medication errors in a paediatric teaching hospital in the UK: Five years operational experience. Arch Dis Child 2000; 83: 492-7.
  • Frey B, Buettiker EV, Hug EM, Waldvogel K, Gessler EP, Ghelfi ED. Does critical encident reporting contribute to medication error prevention. Eur J Pediatr 2002; 161: 594-9.
  • Otero P, Leyton A, Mariani G, Ceriani J. Medication errors in pediatric inpatients: Prevalence and results of a prevention program. Pediatrics 2008; 22: 737-43.
  • Hicks RW, Becker SC, Cousins DD. Harmful medication errors in children: A 5-year analysis of data from the USP's MEDMARXR Program. Journal of Pediatric Nursing 2006; 21: 290-98.
  • Ghaleb M, Barber N, Franklin B, Yeung V, Khaki Z, Wong I. Systematic review of medication errors in pediatric patients. Annals of Pharmacotherapy 2006; 40: 1766-76.
  • Payne C, Smith C, Newkirk L, Hicks R. Pediatric medication errors in the postanesthesia care unit: Analysis of MEDMARX data. AORN Journal 2007; 85: 731-40.
  • Sandlin D. Pediatric medication error prevention. Journal of Peri Anesthesia Nursing 2008; 23: 279-81.
  • Lefrak L. Moving towards safer practice: Reducing medication errors in neonatal care. Journal of Perinatal and Neonatal Nurses 2002; 16: 73−84.
  • Westbrook JI, Woods A, Rob MI, Dunsmuir WT, Day RO. Association of interruptions with an increased risk and severity of medication administration errors. Arch Intern Med 2010; 170: 683-90.
  • Fernald D. Event reporting to a primary care patient safety reporting system, a report from the ASIPS Collaborative. Ann Fam Med 2004; 2: 327-32.
  • Blendon RJ, Desroches CM, Brodie M. Views of practising physicians and the public on medical errors. N Engl J Med 2002; 347: 1993-40.
  • Tutle D, Holloway R, Daird T, Sheehan B, Skelton W. Electronic reporting to improve patient safety. Qualty & Safely in Health Care 2004; 13: 281-86.
  • Zhan C, Hicks RW, Blanchette CM, Keyes MA, Cousins DD. Potential benefits and problems with computerized prescriber order entry: Analysis of a voluntary medication error-reporting database. Am J Health-Syst Pharm 2006; 63: 353-58.
  • Ray MD, Aldrich LT, Lew PJ. Experience with an automated point of use unit dose drug distribution system. Hospital Pharmacy 1995; 30: 18,20-23,27-30.
  • Borel JM, Rascati KL. Effect of an automated nursing unit based drug dispensing device on medication errors. American Journal of Health-System Pharmacy 1995; 52: 1875-187.
  • Sowan AK, Gaffoor MI, Soeken K, Johantgen ME, Vaidya, VU. Impact of computerized orders for pediatric continuous drug infusions on detecting infusion pump programming errors: A simulated study. Journal of Pediatric Nursing 2010; 25: 108-18.
  • Anderson S, Wittwer W. Using barcode point-of-care technology for patient safety. J Health Care Qual 2004; 26: 5-11.
  • Paoletti RD, Suess TM, Lesko MG, Feroli AA, Kennel JA, Mahler JM, et al. Using barcode technology and medication observation methodology for safer medication administration. Am J Health Syst Pharm 2007; 64: 536-43.
  • Savaşer S, Çimen S, Yıldırım S. Flakon şeklindeki antibiyotiklerde kuru toz hacminin uygulanacak doz üzerine etkisi. İ.Ü.F.N. Hem. Dergisi 2008; 16: 7-15.
  • Davidhizar R, Lonser G. Strategies to decrease medication errors. Health Care Manager 2003; 22: 211-18.
  • Uzun Ş, Arslan F. İlaç uygulama hataları. Türkiye Klinikleri J Med Sci 2008; 28: 217-22.
  • The Joint Commission. Preventing pediatric medication errors. Sentinel Event Alert. 2008; April. URL: http://www.jointcommission.org/sentinelevents/sentinel eventalert/sea_39.htm. May 4, 2009.
  • National Coordinating Council for Medication Error Reporting and Prevention. Recommendations to enhance accuracy of administration of medications. 1999; June. URL: http://www.nccmerp.org/council/ council1999-06-29.html. March 29, 2009.
  • Schneider MP, Cotting J, Pannatier A. Evaluation of nurses' errors associated in the preparation and administration of medication in a pediatric intensive care unit. Pharm World Sci 1998; 20: 178-82.
There are 42 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Yrd. Doç. Dr. Ebru Kiliçarslan Törüner This is me

Prof. Dr. Firdevs Erdemir This is me

Publication Date March 1, 2010
Submission Date July 29, 2014
Published in Issue Year 2010 Volume: 17 Issue: 1

Cite

Vancouver Törüner YDDEK, Erdemir PDF. Pediatrik Hastalarda İlaç Uygulama Hatalarının Önlenmesi. HUHEMFAD. 2010;17(1):63-71.