Bacterial Infections and Antibiotic Resistance Rates in SARS-CoV-2 PCR Positive Patients

Abstract

Background: In this study, it was aimed to determine the distribution and antibiotic resistance rates of bacteria isolated from endotracheal aspirate (ETA), blood, catheter samples taken from COVID-19 patients admitted Adana City Training and Research Hospital. Material and method: Between April 1, 2020 and March 31, 2021, 254 patients PCR pozitive patients were included in the study. Blood, catheter and respiratory tract culture growths and antibiotic susceptibility test results were retrospectively analyzed from the microbiology laboratory database. Results: 433 bacterial growths were detected in clinical samples taken from 254 COVID PCR positive patients. Among the bacterial agents, Acinetobacter baumannii (.25.17%; n =109) was the most common pathogens, followed by Escherichia coli (.5.54% n =24) and Klebsiella pneumoniae (.5.31%; n =23). Conclusion: Avoiding unnecessary antibiotic use in COVID 19 patients is critical to prevent resistance development and increase culture sensitivity.

Keywords

• SARS COV2
• COVİD 19
• ANTİBİYOTİK DİRENCİ,
• RT PCR

SARS-CoV-2 PCR Pozitif Hastalarda Bakteriyel Enfeksiyonlar ve Antibiyotik Direnci

Abstract

Amaç ve kapsam: Bu çalışmada Adana Şehir Eğitim ve Araştırma Hastanesin’de yatan COVID-19 hastalarından alınan endotrakeal aspirat (ETA), kan, kateter, örneklerinden izole edilen bakterilerin dağılımını ve antibiyotik direnç oranlarının belirlenmesi amaçlandı. Materyal ve metod: 1 Nisan 2020 ile 31 Mart 2021 tarihleri arasında PCR testi pozitif olarak tesbit edilen 254 hasta çalışmaya dahil edildi. Hastalardan gönderilen kan, katater ve solunum yolu kültür sonuçları ve antibiyotik duyarlılık test sonuçları mikrobiyoloji laboratuvarı veri tabanından retrospektif olarak incelendi. Bulgular: 254 COVİD PCR pozitif hastadan alınan klinik örneklerde 433 bakteri üremesi saptandı. Bakteriyel etkenler arasında, Acinetobacter baumannii (%.25,17; n =109), ardından Esherichia coli (%.5,54 n =24) ve Klebsiella pneumoniae (%.5,31; n =23) en yaygın patojenler olarak tespit edildi Sonuç: COVİD 19 hastarında gereksiz antibiyotik kullanımından kaçınılması direnç gelişiminin önlenmesi ve kültür duyarlılığının artması için kritik öneme sahiptir.

Keywords

• SARS COV-2
• COVİD 19
• RT PCR
• İKİNCİL BAKTERİYEL ENFEKSİYON
• ANTİBİYOTİK DRENCİ

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