Preeklampsi Hastalarındaki Lipit Profili ile Normal Gebe Hastalardaki Lipit Profilinin Karşılaştırılması

Year 2023, , 441 - 445, 31.08.2023

Rahime Kada , Hacer Uyanikoglu

https://doi.org/10.35440/hutfd.1256982

Abstract

Amaç: Preeklamptik gebelerdeki lipit profili ile normal gebelerdeki lipit profilini karşılaştırmak.
Materyal-Metot: Bu çalışma prospektif olarak Harran Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniğinde 2021 Haziran - 2022 Haziran tarihleri arasında hastaneye başvuran 40 ağır preeklamptik, 40 hafif preeklamptik ve 40 sağlıklı gebe hastalardan oluşmuştur. Tüm hastaların yaşı, gebelik ve doğum sayıları, kan basıncı ve nabız değerleri, Vücut Kitle İndeksi(VKİ), kanda total kolesterol, LDL, HDL trigliserit (TG) seviyeleri ve hemogram parametreleri (hemoglobin, hematokrit, WBC, trombosit sayısı ve MPV) değerlendirildi.
Bulgular: Gruplara göre sistolik - diastolik kan basınçları ve nabız değerleri arasında istatistiksel olarak anlamlı fark bulunmuştur (tüm gruplar için p<0.001). Preeklampsi (PE) gruplarında yer alan gebelerin VKİ kontrol grubuna göre daha yüksek olduğu ve gruplara göre VKİ arasında anlamlı fark olduğu ortaya çıkmıştır (p<0.001). Preeklampsili gebelerin total kolesterol, TG ve LDL değerlerinin sağlıklı gebelere göre daha yüksek olduğu, HDL değerlerinin ise sağlıklı gebelere göre daha düşük olduğu belirlenmiştir (p<0.001).
Sonuç: Bu çalışmada PE hastalarındaki lipit profilinin normal gebelerdeki lipit profiline göre daha yüksek çıktığını ve preeklamptik gebelerin daha obez olduğu görülmüştür. Preeklampsili gebelerin lipit profili açısından riskli bir grup olduğu ve doğum sonrası süreçtede takip edilmesi gerektiği sonucuna varılmıştır.

Keywords

Gebe, lipit profili, preeklampsi, vücut kitle indeksi

Comparison of Lipid Profile in Preeclampsia Patients and Lipid Profiles in Normal Pregnant Patients

Abstract

Background: To compare the lipid profile of preeclamptic pregnant women with the lipid profile of normal pregnant women.
Materials and Methods: This study consisted of 40 severe preeclamptic, 40 mild preeclamptic, and 40 healthy pregnant patients who were prospectively admitted to the hospital in Harran University Faculty of Medicine, Department of Obstetrics and Gynecology between June 2021 and June 2022. Age, pregnancy and delivery numbers, blood pressure and pulse values, Body Mass Index (BMI), blood total cholesterol, LDL, HDL triglycer-ide (TG) levels and hemogram parameters (Hemoglobin, Hematocrit, WBC, Platelet count and MPV) of all patients were evaluated.he study was planned as descriptive cross-sectional. The attitudes of the students studying at the Faculty of medicine towards scientific research were questioned. In the study, the ‘’Attitude Scale Towards Scientific Research ‘’ was used.
Results: A statistically significant difference was found between systolic - diastolic blood pressures and heart rate values according to the groups (p<0.001 for all groups). It was found that the BMI of the pregnant women in the preeclampsia (PE) groups was higher than the control group and there was a significant difference between the BMIs according to the groups (p<0.001). It was determined that total cholesterol, TG and LDL values of pregnant women with preeclampsia were higher than healthy pregnant women, and HDL values were lower than healthy pregnant women (p<0.001).
Conclusions: In this study, it was observed that the lipid profile in PE patients was higher than the lipid profile in normal pregnant women, and preeclamptic pregnant women were more obese. It was concluded that pregnant women with preeclampsia are a risky group in terms of lipid profile and should be followed up in the postpartum period.

Key Words: Pregnant, Lipid profile, Preeclampsia, Body mass index

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