The Effect of Comorbidities on Survival of COVİD-19 Patients in the İntensive Care Unit

Abstract

Background: Coronavirus Disease-2019, which affects all parts of the body, is associated with increased mortality. In this study, we aimed to investigate the comorbidities affecting survival in geriatric patients infected with SARS-CoV-2 and admitted to intensive care. Materials and Methods: The medical records of 184 patients hospitalized in the isolated intensive care unit of the Balıkesir University Health Practice and Research Hospital between November 2020 and April 2022 were retrospectively examined. Patients discharged from the intensive care were classified into group 1 and those who died were classified into group 2. The mean age of the 57 patients in group 1 was under 75 years old (74.07±6.86) and was different from group 2. Results: No significant differences in the distribution of chronic obstructive pulmonary disease, coronary artery disease, hypertension, or diabetes mellitus were observed between the groups. Mean ferritin, C-reactive protein, D-dimer, and procalcitonin levels were significantly higher in group 2 than in group 1. No significant differences in fibrinogen levels were observed between the groups. In Group 2, the mean lymphocyte count and number of patients vaccinated against SARS-CoV-2 were significantly lower. Conclusions: We concluded that age is an important determinant of survival. Although vaccination aga-inst the virus is an important factor that increases the likelihood of discharge, it loses its effect if the hospital stay is prolonged.

Yoğun Bakım Ünitesindeki İleri Yaş COVİD-19 Hastalarında Komorbiditelerin Sağkalım Üzerine Etkisi

Abstract

Amaç: Vücudun tüm bölgelerini etkileyen Koronavirüs Hastalığı-2019, artmış mortalite ile ilişkilidir. Bu çalışmada, SARS-CoV-2 ile enfekte olmuş ve yoğun bakıma alınmış yaşlı hastalarda sağkalımı etkileyen komorbiditelerin araştırılması amaçlanmıştır. Materyal ve metod: Kasım 2020 ve Nisan 2022 tarihleri arasında XXX Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi'nin izole yoğun bakım ünitesinde yatan 184 hastanın tıbbi kayıtları retrospektif olarak incelendi. Yoğun bakımdan taburcu edilen hastalar grup 1, hayatını kaybedenler ise grup 2 olarak sınıflandırıldı. Bulgular: Grup 1'deki 57 hastanın ortalama yaşı 75'in altındaydı (74,07±6,86) ve grup 2'den farklıydı. Gruplar arasında kronik obstrüktif akciğer hastalığı, koroner arter hastalığı, hipertansiyon veya diyabetes mellitus dağılımında anlamlı bir fark gözlenmedi. Ortalama ferritin, C-reaktif protein, D-dimer ve prokalsitonin düzeyleri grup 2'de grup 1'e göre anlamlı derecede yüksekti. Gruplar arasında fibrinojen düzeylerinde anlamlı bir fark gözlenmedi. Grup 2'de ortalama lenfosit sayısı ve SARS-CoV-2'ye karşı aşılanmış hasta sayısı anlamlı derecede düşüktü. Sonuç: Yaşın sağkalımın önemli bir belirleyicisi olduğu sonucuna vardık. Virüse karşı aşılanma taburcu olma olasılığını artıran önemli bir faktör olmakla birlikte, hastanede kalış süresinin uzaması durumunda etkisini kaybetmektedir.

Keywords

• yoğun bakım
• COVİD-19
• Komorbidite
• SARS-CoV-2

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