Histopathological Analysis of Hysterectomy Materials in A Tertiary Hospital

Abstract

Introduction: Hysterectomy, a frequently used surgical procedure in gynecology, entails the removal of a part or all of the uterus and is employed in treating various benign and malignant diseases. This study aims to evaluate the histopathological analyses of patients underwent hysterectomy in a tertiary hospital. Aim: This study aimed to investigate the histopathological analysis results of hysterectomy materials and compare them with clinical diagnoses. Methods: The clinical and histopathological data of 107 patients who underwent hysterectomy in a tertiary hospital between January and March 2024 were retrospectively analyzed. The patients' age, hysterectomy type, indication, histopathological diagnosis, and other clinical parameters were recorded. Results: Total laparoscopic hysterectomy (TLH) was the most preferred type of hysterectomy (n=62, %57.94) and patients’ age average was 49.83. Abnormal uterine bleeding (AUB) and myoma uteri was the most prevalent reasons of hysterectomy (n=47, %47.66). While Leiomyoma was the most frequent diagnosis in myometrial lesions (n=52, %47.27), endometrial polyp stood out as the most frequent finding among endometrial lesions. (n=34, %31.77). Conclusion: This study revealed that the histopathological analysis results of hysterectomy materials were largely consistent with clinical diagnoses. AUB and myoma uteri were among the leading indications for hysterectomy. Endometrial polyp stood out as the most common diagnosis among endometrial lesions, whereas leiomyoma emerged as the predominant diagnosis among myometrial lesions.

Keywords

• Hysterectomy
• histopathology
• AUB
• myoma uteri
• endometrial polyp
• leiomyoma.

Üçüncü Basamak Hastanede Histerektomi Materyallerinin Histopatolojik Analizi

Abstract

Giriş: Histerektomi, jinekolojide sıklıkla uygulanan cerrahi bir işlemdir. Uterusun bir kısmının veya tamamının çıkarılmasıdır. Çeşitli benign ve malign hastalıkların tedavisinde kullanılır. Bu çalışmada, üçüncü basamak bir hastanede histerektomi uygulanan hastaların histopatolojik analizleri değerlendirilmiştir. Amaç: Bu çalışmanın amacı, histerektomi materyallerinin histopatolojik analiz sonuçlarını incelemek ve klinik tanılarla karşılaştırmaktır. Yöntem: Bu çalışmada, 2024 yılı Ocak-Mart ayları arasında üçüncü basamak bir hastanede histerektomi uygulanan 107 hastanın klinik ve histopatolojik verileri retrospektif olarak analiz edildi. Hastaların yaş, histerektomi tipi, endikasyon, histopatolojik tanı ve diğer klinik parametreleri kaydedildi. Bulgular: Hastaların yaş ortalaması 49,83 idi. En sık histerektomi tipi total laparoskopik histerektomi (TLH) idi (n=62, %57,94). En sık histerektomi endikasyonları anormal uterin kanam (AUK) ve myoma uteri idi (n=47, %47,66). Endometriyal lezyonlar arasında en sık endometrial polip (n=34, %31,77) saptandı. Myometriyal lezyonlarda ise leiomyoma en sık tanıydı (n=52, %47,27). Sonuç: Bu çalışmada, histerektomi materyallerinin histopatolojik analiz sonuçlarının klinik tanılarla büyük ölçüde uyumlu olduğu gözlendi. Anormal uterin kanama(AUK) ve myoma uteri, histerektomi endikasyonları arasında en ön sıralarda yer aldı. Endometriyal lezyonlar arasında endometrial polip, myometriyal lezyonlar arasında ise leiomyoma en sık tanıydı.

Keywords

• Histerektomi
• histopatoloji
• endometrial hiperplazi
• uterus kanaması
• miyom

References

1. 1. Wu JM, Wechter ME, Geller EJ, Nguyen TV, Visco AG. Hysterec-tomy rates in the United States, 2003. Obstet Gynecol. 2007;110:1091-5.
2. 2. Sarfraz T, Tariq H. Histopathological findings in menorrhagia: A study of 100 hysterectomy specimens. Pak J Pathol. 2005;16:83-5.
3. 3. Shahid R, Abbas H, Mumtaz S, Perveen F, Bari MF, Raja T, et al. Hysterectomy and Oophorectomy in Reproductive Age: A Cross-Sectional Study from a Tertiary Care Hospital. Cureus. 2020;12(5):e8344. doi: 10.7759/cureus.8344.
4. 4. Balcı O. Comparison of total laparoscopic hysterectomy and abdominal hysterectomy. Turk J Obstet Gynecol. 2014;11(4):224-227. doi:10.4274/tjod.47108.
5. 5. Ramachandran T, Sinha P, Subramanium. Correlation between clinicopathological and ultrasonographical findings in hysterec-tomy. J Clin Diag Res. 2011; 5:737-40.
6. 6. Dhuliya V, Gosai D, Jain H, Goswami H. Histopathological study of uterine and cervical lesion in hysterectomy specimen. BJKines-National Journal of Basic & Applied Science. 2016;8:23-6.
7. 7. Johnson N, Barlow D, Lethaby A, Tavender E, Curr E, Garry R. Surgical approach to hysterectomy for benign gynaecological disease. Cochrane Database Syst Rev. 2006;(2):CD003677. doi: 10.1002/14651858.CD003677.pub3. Update in: Cochrane Da-tabase Syst Rev. 2009;(3):CD003677.
8. 8. Committee Opinion No 701: Choosing the Route of Hysterec-tomy for Benign Disease. Obstet Gynecol. 2017;129(6):e155-e159. doi: 10.1097/AOG.0000000000002112.

9. 9. Deffieux X, Rochambeau Bd, Chene G, Gauthier T, Huet S, Lamblin G, et al. Hysterectomy for benign disease: clinical prac-tice guidelines from the French College of Obstetrics and Gy-necology. Eur J Obstet Gynecol Reprod Biol. 2016;202:83-91. doi: 10.1016/j.ejogrb.2016.04.006.
10. 10. Wright JD, Herzog TJ, Tsui J, Ananth CV, Lewin SN, Lu YS, et al. Nationwide trends in the performance of inpatient hysterec-tomy in the United States. Obstet Gynecol. 2013;122(2 Pt 1):233-241. doi: 10.1097/AOG.0b013e318299a6cf.
11. 11. Patel AS, Shah KJ. Histopathological analysis of hysterectomy specimens in tertiary care center: two- year study. Trop J Pathol Microbiol. 2018;4:34-9.
12. 12. Vani D, Pushpa HR, Srijana Rao SP, Bharathi M. Spectrum of histopathological findings in hysterectomy specimens - a retro-spective - 5-year study. J Med Sci Clin Res. 2018;6:902-6.
13. 13. Shrestha A, Shrestha R, Sedhai LB, Pandit U. Adenomyosis at hysterectomy: prevalence, patient characteristics, clinical pro-file and histopathological findings. Kathmandu Univ Med J. 2012;37:53-6.
14. 14. Shergill SK, Shergill HK, Gupta M, Kaur S. Clinicopathological study of hysterectomies. J Indian Med Assoc. 2002;100:238-39.
15. 15. Jaleel R, Khan A, Soomro N. Clinicopathological study of ab-dominal hysterectomies. Pak J Med Sci. 2009;25:630-34.