Spontan ve invitro fertilizasyon ikiz gebeliklerinde gebeliğe ait ve neonatal verilerin karşılaştırılması

Abstract

Amaç: Bu çalışmanın amacı invitro fertizasyon(IVF) tedavisi ile gerçekleşen ikiz gebelikler ile

spontan gerçekleşen ikiz gebeliklerin gebelik ve perinatal dönem bulguları açısından

karşılaştırılmasıdır.

Materyal ve Method: Bu çalışma, 2015-2018 yılları arasında, canlı doğumu gerçekleşen dikoryonik

diamniotik ikiz gebeliklerin verileri incelenerek gerçekleştirilmiş bir retrospektif kohort çalışmasıdır.

Bu araştırmada gebeliği spontan olarak gerçekleşmiş ikiz gebelikler grubu ve yardımcı üreme

teknikleri kullanılarak gebe kalmış IVF ikiz grubu olmak üzere iki çalışma grubu vardır

Bulgular: Gebeliğe ve doğuma ait problemler her iki grup arasında farklılık göstermemiştir. IVF ikiz

gebeliklerinde prematurite, düşük doğum ağırlığı ve 1. Dakika APGAR skor düşüklüğü oranlarının

daha fazla olduğu görülmüştür. Perinatal mortalite oranları her iki grupta benzer bulunmuştur.

Sonuç: Bu çalışmada gösterilmiştir ki; ikiz gebeliklerde tek gebeliklere göre zaten daha yüksek

riske sahip olan erken doğum ve düşük doğum ağırlığı riskleri, IVF ikiz gebeliklerinde daha da fazla

artmaktadır. Bu sonuçlar gözönüne alınarak tek embryo transferine yönelmek ve iatrojenik çoğul

gebeliklere destek vermemek önerilmelidir.

Keywords

• IVF,İkiz gebelikler,tekil gebelikler,neonatal sonuçlar

Comparison of pregnancy and neonatal outcome in spontaneous and invitro fertilization (IVF) twin pregnancies

Abstract

Background: This study aimed to investigate whether the differences between twin

invitrofertilization (IVF) and twin spontaneous pregnancies in terms of pregnancy and perinatal

outcome.

Material and Methods: This is a retrospective cohort study carried out by examining the data of

dichorionic-diamniotic twin pregnancies with live births in a private hospital between 2015 and 2018.

There were two study groups which were the twin pregnancy group with spontaneous pregnancy

and the IVF twin group with pregnancy via assisted reproductive techniques.

Results: Pregnancy and birth problems did not differ between the two groups. The IVF twin

pregnancies were observed to have higher rates of preterm birth, low birthweight and APGAR 1st

minute scores. Perinatal mortality rates were found similar in both groups.

Conclusion: In conclusion, it was shown in this study that the risks of preterm birth and low

birthweight which are already higher in twin pregnancies than in singleton pregnancies were even

higher in the IVF twin pregnancies. It is recommended in accordance with these results that single

embryo transfers should be preferred and iatrogenic multiple pregnancies should not be

encouraged.

Keywords

• Twin pregnancies,single pregnancies,IVF,neonatal outcome

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