Factors Affecting The Change in Agatson Score in Follow Up Multislice Coronary Ct Angiograms

Abstract

Background: Coronary calcium shows the atherosclerosis burden in coronary arteries and is associated with adverse cardiac events. Agatston score is the most widely used scoring sys-tem to quantify coronary artery calcium. In this study, we aimed to establish the factors associated with the change in Agatston score in time.
Materials and Methods: Patients who underwent multiple coronary computerized tomo-graphic angiographies and had Agatston score measurements were included in the study. The change of Agatston score was compared among cardiovascular risk groups. Linear regres-sion model was formed to detect independent variables affecting the change in Agatston score.
Results: A total of 126 patients were included in the study. 63 patients had zero baseline Agatston score. Patients with hypertension, diabetes or previous coronary artery disease history had significantly higher Agatston score changes than those without. Age and previous coronary artery disease increased the risk of Agatston score increase over time whereas zero baseline Agatston score decreased the risk.
Conclusions: Age and previous coronary artery disease history are independent risk factors for the increase in Agatston score over time. Baseline Agatston score of zero decreases the risk of subsequent increase in Agatston score.

Keywords

• Agatston score
• Coronary artery calcium
• Cardiovascular risk factor
• Agatston score, Coronary artery calcium, Cardiovascular risk factor

Çok Kesitli Koroner Bt Anjiyografilerde Takipte Agatston Skorunun Değişimine Etki Eden Faktörler

Abstract

Amaç: Koroner kalsiyum skoru koroner arterlerdeki ateroskleroz yükünü gösterir ve olumsuz kardiyak olaylar ile ilişkilidir. Agatston skoru koroner arterlerdeki kalsifikasyonun sayısal de-ğerlendirmesi için en sık kullanılan skorlama sistemidir. Bu çalışmada zaman içerisinde Agats-ton skorundaki değişime etki eden faktörleri saptamayı amaçladık.
Materyal ve Metod: Zaman içerisinde birden fazla koroner bilgisayarlı anjiyografi çekimi ya-pılmış ve Agatston skoru hesaplanmış hastalar çalışmaya alındı. Agatston skorundaki değişim farklı kardiyovasküler risk grupları içerisinde karşılaştırıldı. Agatston skorundaki değişime etki eden değişkenleri saptamak için doğrusal regresyon modeli oluşturuldu.
Bulgular: 126 hasta çalışmaya dahil edildi. 63 hastanın bazal Agatston skoru sıfırdı. Hipertansi-yon, diyabet veya daha önce koroner arter hastalığı öyküsü olan hastalarda olmayanlara göre Agatston skorundaki değişim anlamlı olarak daha fazlaydı. Yaş ve daha önce koroner arter hastalığı öyküsü olması zaman içerisinde Agatston skorunda artış riskini arttırırken, bazal Agatston skorunun sıfır olması bu riski azaltmaktaydı.
Sonuç: Yaş ve daha önce koroner arter hastalığı öyküsü olması Agatston skorunda zaman içerisinde artış için bağımsız risk faktörleridir. Bazal Agatston skorunun sıfır olması ise takipte Agatston skorunun artış riskini azaltmaktadır.

Anahtar kelimeler: Agatston skoru, Koroner arter kalsiyumu, Kardiyovasküler risk faktörü

Keywords

• Agatston score
• coronary artery calcium
• cardiovascular risk factor

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