Porselen Kese Zemininde Safra Kesesi Kanserlerinin Nadir Görülen Varyantı; Skuamöz Hücreli Kanser

Year 2016, Volume: 13 Issue: 1, 88 - 94, 28.04.2016

Ersen Ertekin Nurdan Fidan

Abstract

Amacımız, porselen kese zemininde skuamöz hücreli safra kesesi kanseri olgumuzun radyolojik bulgularını
ve literatür eşliğinde safra kesesi kanserlerine yaklaşımı gözden geçirmektir. Safra kesesi kanserleri
gastrointestinal tümörlerin 5. sıklıkta görülen, safra yollarının ise en sık görülen maligniteleridir. 6. dekad ve
sonrasında, kadınlarda daha sık gözlenmektedir. Çoğu asemptomatik olmakla beraber semptomatik olanlar
genellikle sağ üst kadran ağrısı, sarılık, kilo kaybı semptomları ile başvururlar. Görüntüleme bulguları sıklık
sırasına göre; kese lojunu dolduran kitle, fokal ya da diffüz duvar kalınlaşması ve luminal kitledir. En sık
görülen tip (%85 üzeri) adenokarsinomdur. Geri kalanlar skuamöz/adenoskuamöz, undiferansiye ve diğer
başlığı altında toplanabilir. Genellikle geç tanı konması sebebiyle prognoz kötüdür. Olguların çoğunun
asemptomatik olması, semptomatik olanların diğer benign safra yolu hastalıkları ile benzerlik
göstermesinden dolayı tanı gecikmektedir. Görüntüleme bulgularının iyi yorumlanması, klinik hikaye ile
birleştirilerek erken tanı konması, prognozu kötü olan bu kanser tipinde sağkalıma katkı sağlayacaktır.

Keywords

Safra kesesi, Safra kesesi tümörleri, Skuamöz hücreli karsinom

An Uncommon Variant Of Gallbladder Cancer On The Basis Of Porcelain Gallbladder; Squamous Cell Cancer

Abstract

Our goal is to review gallbladder cancer (GBC) approach accompanied by radiological findings of the case of
th
squamous cell gallbladder cancer on the basis of porcelain gallbladder and the literature. GBC is the 5 most
common gastrointestinal tumors and the most common malignancy of the bile ducts. GBC observed after the
6. decades and more frequently seen among females. Although most cases of asymptomatic, symptomatic
ones are usually refers with right upper quadrant pain, jaundice and weight loss. Imaging findings in order of frequency are the mass that fills the gallbladder fossa, focal or diffuse thickening of the wall and luminal
polypoid mass. The most common type is adenocarcinoma (above 85%). The rest can be grouped under the
title of squamous/adenosquamous, undifferentiated and the others. The diagnosis delayed, because most of
the cases are asymptomatic and the symptomatic ones have similarities with other benign biliary tract
diseases. Generally, the prognosis is poor due to late diagnosis. With good interpretation of imaging findings
and combined with the clinical story, early diagnosis should be made and it will be contribute to the survival
in this type of poor prognosis cancer.

Keywords

Gallbladder, Gallbladder Neoplasms, Squamous Cell Carcinoma

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