BibTex RIS Cite

Epidural Yöntemle Yapılan Ağrısız Normal Doğum Mean Platelet Volum Düzeyini Etkiler Mi?

Year 2014, Volume: 11 Issue: 2, 118 - 122, 01.08.2014

Abstract

Amaç: Respiratuar distres sendromu, kronik obsturiktif akciğer hastalığının akut alevlenmesi, akut pankreatit ve sepsis gibi birçok hastalığın MPV ile ilişkisi araştırılmıştır. MPV'nin diğer inflamatuar markerlarına göre daha ucuz ek maliyet getirmeyen bir inflamatuar marker olduğu gösterilmiştir. Epidural yolla yapılan ağrısız normal doğum esnasında oluşan MPV değişikliklerini araştırmayı amaçladık.Materyal Metod: Hastanemizde spontan vajinal doğum yapan ve epidural yolla ağrısız doğum yapan hastalar retrospektif olarak incelendi. Hastaların yaş, ağırlık, ,boy, gebelik haftaları, doğumun birinci, ikinci, üçüncü evrelerinin süreleri, bebelerin doğum ağırlıkları, hastaların doğum için hastaneye ilk başvurularındaki MPV değerleri ile postpartum 24. saatteki MPV değerleri kaydedildi.Bulgular: Demografik veriler açısından her iki grubta da anlamlı bir fark yoktu. Her iki grupta da MPV değerleri bazal değerlere kıyasla 24. saatte yükselmişti fakat iki grup arasında istatistiksel olarak fark yoktu.Sonuç: MPV doğuma bağlı inflamatuar yanıtı araştırmada bir marker olarak kullanılabilir

References

  • ) Şükran Şahin ,Doğum Ağrısının Mekanizması ve Etkileri;Şükran Ş.,Medge D Owen Ağrısız Doğum ve Sezaryende Anestezi,Nobel &Güneş 2006;11-22
  • ) Tavasolli M. Modulation of megacaryocyte amp. Peripolesis by phleobo-tomy: Megacaryocytes as a component of marrow-blood barrier. Blood Cells. ;12(1):205-16. ) Paulus JM, Bury J, Grosdent JC. Control of platelet territory development in me-gakaryocytes. Blood Cells ;5(1):59-88. ) Cole JL, Marzec UM, Gunthel CJ, Karpatkin S, Worford L, Sundell IB et al. Inef-fective platelet p r o d u c t i o n i n t h r o m b o c y t o p e n i c h u m a n immunodeficiency virus-infected patients. Blood ;91(9):3239-46.
  • ) Ulasli SS, Ozyurek BA, Yilmaz EB, Ulubay G. Mean platelet volume as an inflammatory marker in acute exacerbation of chronic obstructive pulmonary disease. Pol Arch Med Wewn. 2012;122(6):284-90.
  • ) Canbolat FE, Yurdakok M, Armangil D, Yigit S. Mean platelet volume in neonatal respiratory distress syndrome. Pediatrics International, 2009;51(2):314-6
  • ) Beyazit Y, Sayilir A, Torun S, Suvak B, Yesil Y at al. Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis. Clin Res Hepatol Gastroenterol, 2012 Apr;36(2):162-8
  • ) Guida JD, Kunig AM, Leef KH, Mckenzie SE, Paul DA. Platelet count and sepsis in very low birth weight neonates: ıs there an organism-specific response? Pediatrics, 2003;111(6):1411-5
  • ) Yıldıhan R, Yıldızhan B, Turan YB. Doğumda epidural analjezi. Van Tıp Dergisi: 2008;15 (4):116-9
  • ) Yokoyoma M, Itano Y, Katayama H et al. The effects of continuous epidural anesthesia and analgesia on stress response and immune function in patients undergoing r a d i c a l e s o p h a g e c t o m y . A n e s t h A n a l g ;101(5):1521-7.
  • ) Beilin B, Shavit Y, Trabekin E et al. The effects of postoperative pain managment on immune response to surgery. Anesth Analg 2003;97(3):833-7.
  • ) Dundar O, Yoruk P, Tutuncu L, Erikci AA, Muhcu M, Ergur AR, Atay V, Mungen E. Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsia. Prenat Diagn. 2008;28(11):1052-6.
  • ) Vogl SE, Worda C, Egarter C, Bieglmayer C, Szekeres T, Huber J, Husslein P. Mode of delivery is associated with maternal and fetal endocrine stress response. BJOG. ;113(4):441-5. ) Halpern SH,Leighton BL ,Ohlsson A, et all:Effect of epidural vs.parenteral opioid analgesia on the progres of labor .JAMA 1998 ;280(24):2105-10

Does Spontaneous Vaginal Delivery with Epidural Analgesia Effect The Mean Platelet Values ?

Year 2014, Volume: 11 Issue: 2, 118 - 122, 01.08.2014

Abstract

Backgrounds: Relationship between MPV and many diseases such as; respiratory distress syndrome, acute exacerbations of chronic obstuctive lung disease , acute pancreatitis and sepsis was investigated. And it has been shown that MPV is cheaper than the other inflammatory markers and does not bring additional cost. We aimed to study the changes of MPVvalues during vaginal delivery with epidural anesthesia. Methods: Patients who had spontaneous vaginal deliveries with/ without epidural anesthesia in our hospital were retrospectively analyzed. Patients' age, weight, height, gestational week, duration of first-second-third th stages of labor, weight of babies, MPV values that when they admitted to hospital and 24 hours at postpartum. Results: There was no difference in terms of demographic datas between the groups. MPV values increased th in both groups when compared with baseline values at 24 hour but this was not statistically significant. Conclusion: MPVcan be used as a marker for researching labor-related inflammatory response

References

  • ) Şükran Şahin ,Doğum Ağrısının Mekanizması ve Etkileri;Şükran Ş.,Medge D Owen Ağrısız Doğum ve Sezaryende Anestezi,Nobel &Güneş 2006;11-22
  • ) Tavasolli M. Modulation of megacaryocyte amp. Peripolesis by phleobo-tomy: Megacaryocytes as a component of marrow-blood barrier. Blood Cells. ;12(1):205-16. ) Paulus JM, Bury J, Grosdent JC. Control of platelet territory development in me-gakaryocytes. Blood Cells ;5(1):59-88. ) Cole JL, Marzec UM, Gunthel CJ, Karpatkin S, Worford L, Sundell IB et al. Inef-fective platelet p r o d u c t i o n i n t h r o m b o c y t o p e n i c h u m a n immunodeficiency virus-infected patients. Blood ;91(9):3239-46.
  • ) Ulasli SS, Ozyurek BA, Yilmaz EB, Ulubay G. Mean platelet volume as an inflammatory marker in acute exacerbation of chronic obstructive pulmonary disease. Pol Arch Med Wewn. 2012;122(6):284-90.
  • ) Canbolat FE, Yurdakok M, Armangil D, Yigit S. Mean platelet volume in neonatal respiratory distress syndrome. Pediatrics International, 2009;51(2):314-6
  • ) Beyazit Y, Sayilir A, Torun S, Suvak B, Yesil Y at al. Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis. Clin Res Hepatol Gastroenterol, 2012 Apr;36(2):162-8
  • ) Guida JD, Kunig AM, Leef KH, Mckenzie SE, Paul DA. Platelet count and sepsis in very low birth weight neonates: ıs there an organism-specific response? Pediatrics, 2003;111(6):1411-5
  • ) Yıldıhan R, Yıldızhan B, Turan YB. Doğumda epidural analjezi. Van Tıp Dergisi: 2008;15 (4):116-9
  • ) Yokoyoma M, Itano Y, Katayama H et al. The effects of continuous epidural anesthesia and analgesia on stress response and immune function in patients undergoing r a d i c a l e s o p h a g e c t o m y . A n e s t h A n a l g ;101(5):1521-7.
  • ) Beilin B, Shavit Y, Trabekin E et al. The effects of postoperative pain managment on immune response to surgery. Anesth Analg 2003;97(3):833-7.
  • ) Dundar O, Yoruk P, Tutuncu L, Erikci AA, Muhcu M, Ergur AR, Atay V, Mungen E. Longitudinal study of platelet size changes in gestation and predictive power of elevated MPV in development of pre-eclampsia. Prenat Diagn. 2008;28(11):1052-6.
  • ) Vogl SE, Worda C, Egarter C, Bieglmayer C, Szekeres T, Huber J, Husslein P. Mode of delivery is associated with maternal and fetal endocrine stress response. BJOG. ;113(4):441-5. ) Halpern SH,Leighton BL ,Ohlsson A, et all:Effect of epidural vs.parenteral opioid analgesia on the progres of labor .JAMA 1998 ;280(24):2105-10
There are 11 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Serdar Kokulu This is me

Elif Doğan Baki This is me

Bekir Serdar Ünlü This is me

Hasan Şenay This is me

Gülengül Köken This is me

Publication Date August 1, 2014
Published in Issue Year 2014 Volume: 11 Issue: 2

Cite

Vancouver Kokulu S, Baki ED, Ünlü BS, Şenay H, Köken G. Epidural Yöntemle Yapılan Ağrısız Normal Doğum Mean Platelet Volum Düzeyini Etkiler Mi?. Harran Üniversitesi Tıp Fakültesi Dergisi. 2014;11(2):118-22.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty