Subkorneal püstüler dermatoz; tekrarlayıcı özellikteki püstüler erüpsiyonlar ve histopatolojik olarak çok sayıda nötrofil içeren subkorneal yerleşimli püstüller ile karakterize, seyrek görülen kronik bir dermatozdur. Nedeni bilinmeyen hastalık; özellikle karın, aksilla ve kasıklarda yerleşen, bilateral ve simetrik, annüler veya serpiginöz plaklar ile seyreder. Bu yazıda; karakteristik histopatolojik bulgular gösteren ve bir yıldır yayılım göstermeden seyreden 4o yaşında bayan subkorneal püstüler dermatoz olgusu, atipik yerleşim ve klinik özellikler göstermesi nedeni ile sunulmuştur
) Cohen L, Skopicki DK, Harrist TJ, Clark Jr WH. Noninfectious vesiculobullous and vesiculopustular diseases. In: Elder D, Elenitsas R, Jaworsky C, Johnson B (eds). Lever's histopatology of the skin, 8 ed. New York: Lippincott-Raven. 1997; 209-52.
) Wallach D. Subcorneal pustulosis and monoclonal gammapathies. AnnMedIntern. 1984; 135: 672-6
) Ratnarathorn M, Newman J. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) occurring in association with nodal marginal zone lymphoma: a case report. Dermatol Online J. 2008; 14: 6
) Koçak M, Birol A, Erkek E, et al. Juvenile subcorneal pustular dermatosis: a case report. Pediatr Dermatol. ; 20: 57-9. ) Honeycutt WM. Jonsen GT: Subcorneal pustular dermatosis ın: Demis DJ(ed). Clinical Dermatology. Happer and Row Publ. 1987; 6-2
) Khachemoune A, Blyumin ML. Sneddon-Wilkinson disease resistant to dapsone and colchicine successfully controlled with PUVA. Dermatol Online J. 2003; 9:24.
) Hönigsmann H, Trautinger F, Wolff K. Sobcorneal pustular dermatosis (Sneddon-Wilkinson Disease). In: Fitzpatrick T, Eisen A,Wolff K, Freedberg MI, Austen FK (eds). Dermatology in general medicine, 4 ed. New- York:McGraw Hill. 1999; 719-22.
) Trautinger F, Hönigsmann H. Sub-corneal pustular dermatosis (Sneddon-Wilkinson disease). In: Wolff K, Goldsmith LA, Katz SI, et al. editors. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York: McGraw Hill. 2008; 305-7.
) Takematsu H, Tagami H. Quantification of chemotactic peptides (C5a anaphylatoxin and IL-8) in psoriatic lesional skin. Arch Dermatol. 1993; 129: 74-80.
) Folkers E, Tafelkruyer J. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease)--therapeutic problems. Br J Dermatol. 1978; 98: 681-4.
) Teixeira M, Lves RA, Seloresi M. Subcorneal pustular dermatosis in association with a monoclonal IgA/k gammopathy: successful treatment with acitretin. Eur J Dermatol. 2006; 16: 588-90.
) Voigtländer C, Lüftl M, Schuler G, et al. Infliximab (antitumor necrosis factor alpha antibody): a novel, highly effective treatment of recalcitrant subcorneal pustular dermatosis (Sneddon-Wilkinson disease). Arch Dermatol. ; 137: 1571-4.
) Marlier V, Beylot-Barry, Beylot C, Doutre M. Succesfull treatment of subcorneal dermatosis (Sneddon- Wilkinson disease) by acitretin: report of a case. Dermatology. 1999; 199: 153-5.
Subcorneal pustular dermatosis: An atypical case report
Year 2014,
Volume: 11 Issue: 1, 71 - 74, 01.04.2014
Subcorneal pustular dermatosis is an uncommon and chronic disease with unknown etiology, characterized by recurrent pustular eruption and subcorneal pustules that contain abundant neutrophils histopathologically. Annular or serpiginous plaques are observed symmetrically with a predilection of axilla, abdomen and groins. We describe a 40-year famale patient with an non-spreading plaque, showing characteristic features of subcorneal pustular dermatosis histopathologically findings
) Cohen L, Skopicki DK, Harrist TJ, Clark Jr WH. Noninfectious vesiculobullous and vesiculopustular diseases. In: Elder D, Elenitsas R, Jaworsky C, Johnson B (eds). Lever's histopatology of the skin, 8 ed. New York: Lippincott-Raven. 1997; 209-52.
) Wallach D. Subcorneal pustulosis and monoclonal gammapathies. AnnMedIntern. 1984; 135: 672-6
) Ratnarathorn M, Newman J. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) occurring in association with nodal marginal zone lymphoma: a case report. Dermatol Online J. 2008; 14: 6
) Koçak M, Birol A, Erkek E, et al. Juvenile subcorneal pustular dermatosis: a case report. Pediatr Dermatol. ; 20: 57-9. ) Honeycutt WM. Jonsen GT: Subcorneal pustular dermatosis ın: Demis DJ(ed). Clinical Dermatology. Happer and Row Publ. 1987; 6-2
) Khachemoune A, Blyumin ML. Sneddon-Wilkinson disease resistant to dapsone and colchicine successfully controlled with PUVA. Dermatol Online J. 2003; 9:24.
) Hönigsmann H, Trautinger F, Wolff K. Sobcorneal pustular dermatosis (Sneddon-Wilkinson Disease). In: Fitzpatrick T, Eisen A,Wolff K, Freedberg MI, Austen FK (eds). Dermatology in general medicine, 4 ed. New- York:McGraw Hill. 1999; 719-22.
) Trautinger F, Hönigsmann H. Sub-corneal pustular dermatosis (Sneddon-Wilkinson disease). In: Wolff K, Goldsmith LA, Katz SI, et al. editors. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York: McGraw Hill. 2008; 305-7.
) Takematsu H, Tagami H. Quantification of chemotactic peptides (C5a anaphylatoxin and IL-8) in psoriatic lesional skin. Arch Dermatol. 1993; 129: 74-80.
) Folkers E, Tafelkruyer J. Subcorneal pustular dermatosis (Sneddon-Wilkinson disease)--therapeutic problems. Br J Dermatol. 1978; 98: 681-4.
) Teixeira M, Lves RA, Seloresi M. Subcorneal pustular dermatosis in association with a monoclonal IgA/k gammopathy: successful treatment with acitretin. Eur J Dermatol. 2006; 16: 588-90.
) Voigtländer C, Lüftl M, Schuler G, et al. Infliximab (antitumor necrosis factor alpha antibody): a novel, highly effective treatment of recalcitrant subcorneal pustular dermatosis (Sneddon-Wilkinson disease). Arch Dermatol. ; 137: 1571-4.
) Marlier V, Beylot-Barry, Beylot C, Doutre M. Succesfull treatment of subcorneal dermatosis (Sneddon- Wilkinson disease) by acitretin: report of a case. Dermatology. 1999; 199: 153-5.