BibTex RIS Cite

Cerrahi Branşlara Göre Yapılan Ameliyatlarda Antibiyotik Proflaksi Klavuzu

Year 2008, Volume: 5 Issue: 1, 43 - 54, 01.04.2008

Ali Uzunköy

Abstract

Genel cerrahi operasyonları temiz yaralardan, kirli yaralara kadar geniş bir alana yayılmıştır. Proflaksi seçiminde en önemli faktör yaranın kontaminasyon derecesidir. Temiz cerrahi yaralar için seçilecek antibiyotik Sefazolin veya Sefuroksim’dir. Özellikle kolorektal cerrahide barsak hazırlığı ile birlikte anaeroblara etkili bir antibiyotiğin Metranidazol, Ornidazol gibi seçilmesi önerilmektedir. Tiroidektomide, splenektomide antibiyotik proflaksisi önerilmemektedir. Fıtık ameliyatlarında greft kullanılmamış ise proflaksiye gerek yoktur. Meme cerrahisinde de proflaksi önerilmemektedir. Bununla birlikte fıtık cerrahisi ve meme cerrahisinde proflaksi uygulayanlar vardır. Yüksek selektif vagatomi ve Nissen fundoplikasyonunda da AP önerilmektedir. Karaciğer ve pankreas cerrahisinde proflaksi uygulaması tartışmalıdır.

References

  • Antibiotic prophylaxis in surgery.
  • www.sign.ac.uk/guidelines/fulltext Antibiotic prophylaxis in surgery: A national
  • http://www.guideline.gov 3.
  • guideline. KLİMİK Akılcı antibiyotik kullanımı, konferans notları 4.
  • Preclik G, Grune S, Leser HG, Lebherz J, Heldwein W, Machka K, et al. Prospective, randomised, double blind trial of prophylaxis with single dose of co-amoxiclav before percutaneous endoscopic gastrostomy. BMJ 1999; 319: 881-4.
  • Platt R, Zucker JR, Zaleznik DF, Hopkins CC, Dellinger EP, Karchmer AW, et al. Perioperative antibiotic prophylaxis and wound infection following breast surgery. J Antimicrob Chemother 1993; 31: 43-8. 6.
  • Aufenacker TJ, van Geldere D, van Mesdag T, Bossers AN, Dekker B, Scheijde E, van Nieuwenhuizen R, Hiemstra E, Maduro JH, Juttmann JW, Hofstede D, van Der Linden CT, Gouma DJ, Simons MP.The role of antibiotic prophylaxis in prevention of wound infection after Lichtenstein open mesh repair of primary inguinal hernia: a multicenter double-blind randomized controlled trial. Ann Surg 2004; 240:955-61 7.
  • Meijer WS, Schmitz PI, Jeekel J. Meta- analysis of randomised, controlled clinical trials of antibiotic prophylaxis in biliary tract surgery. Br J Surg 1990; 77: 283-90.
  • Colizza S, Rossi S, Picardi B, et al. after Surgical
  • cholecystectomy: ceftriaxone vs ceftazidime antibiotic prophylaxis. A prospective study. Chir Ital 2004; 56:397-402.
  • laparoscopic Edmiston CE, Krepel C, Kelly H, et al. Perioperative antibiotic prophylaxis in the gastric bypass patient: do we achieve therapeutic levels? Surgery. 2004;136:738-47.
  • Wasey N, Baughan J, de gara CJ. Prophylaxis in elective colorectal surgery: the cost of ignoring the evidence. Can J Surg. 2003 ; 46:279-84. 11. Hernandez
  • Pharmacokinetics and tissue penetration of pefloxacin plus metronidazole after administration as surgical prophylaxis in colorectal surgery. Int J Clin Pharmacol Ther. 2003; 41:267-74.
  • JL. Andersen BR, Kallehave FL, Andersen HK. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev. 2003;:CD001439.
  • Pessaux P, Mska S, Atalla D, et al. Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients. Arch Surg. 2003;138:314-24. 14.
  • RA, et al. Placebo-controlled, double-blind, randomized study of prophylactic antibiotics in elective abdominal hysterectomy. J Hosp Infect. 2002;52:302-6. 15.
  • Amoxicillin/clavulanic acid versus cefotaxime for antimicrobial prophylaxis in abdominal surgery: a randomized trial. J Chemother. 2002;14:366-72.
  • Sganga G. New perspectives in antibiotic prophylaxis for intra-abdominal surgery. J Hosp Infect. 2002;50 Suppl A:S17-21. 17.
  • prophylaxis for abdominal surgery: is there a need for metronidazole?J Chemother. 2001;13:27-34. 18.
  • prophylaxis and treatment of surgical abdominal sepsis. J Chemother. 2001;13 :193-201. 19.
  • retrospective study on the efficacy of short-term perioperative prophylaxis in abdominal surgery for hernia repair in 1,254 patients. J Chemother 2000;12:34-7. 20.
  • prophylaxis with ceftriaxone in laparoscopic cholecystectomy: a 7-year clinical experience involving 3,603 patients. J Chemother. 2000;12:17- 22. U.
  • Antimicrobial Colizza S, Rossi S.
  • Antibiotic Gervino L, Cangioni G, Renzi F. A Farello GA, Cerofolini A. Antimicrobial Dellinger PE, Gross PA, Barrett TL, Krause PJ, Martone WJ, McGowan JE et al. Quality standard for antimicrobial prophylaxis in surgical procedures. Clin Infect Dis 1994; 422-7. 22.
  • Delahaye F, Chevalier P, Cerisier A, et al. Antibiotic prophylaxis for permanent pacemaker implantation: a meta-analysis. Circulation 1998; 97: 1796-801.
  • Penketh AR, Wansbrough-Jones MH, Wright E, Imrie F, Pepper JR, Parker DJ. Antibiotic prophylaxis for coronary artery bypass graft surgery. Lancet 1985; 1: 1500.
  • Ilves R, Cooper JD, Todd TR, Pearson FG. Prospective, randomised, double-blind study using prophylactic cephalothin for major, elective, general thoracic operations. J Thorac Cardiovasc Surg 1981; 81: 813-7. 25.
  • Gimferrer JM, Aznar E, et al. Antibiotic prophylaxis in non-cardiac thoracic surgery: cefazolin versus placebo. Eur J Cardiothorac Surg 1991; 5: 515-8.
  • Da Costa A, Kirkorian G, Cucherat M, Delahaye F, Chevalier P, Cerisier A, et al. Antibiotic prophylaxis for permanent pacemaker implantation: a meta-analysis. Circulation 1998; 97: 1796-801. 27.
  • Gimferrer JM, Aznar E, et al. Antibiotic prophylaxis in non-cardiac thoracic surgery: cefazolin versus placebo. Eur J Cardiothorac Surg 1991; 5: 515-8. 28.
  • I. Perioperative prophylactic cephazolin in spinal surgery. A double-blind placebo-controlled trial. J Bone Joint Surg Br 1994; 76: 99-102
  • Ritche S, Scalon N, Lewis M, Black PN. Use of a preprinted sticker to improve the prescribing of prophylactic antibiotics for hip fracture 2004;13:384-7. 30.
  • prophylaxis reduces infectious complications in caesarean delivery. Evidence-Based Medicine 1999; 4: 179. Saf Health Care Burrows RF. Review
  • antibiotic Lofgren M, Poromaa IS, Stjerndahl JH, Renstrom B. Postoperative infections and antibiotic prophylaxis for hysterectomy in Sweden: a study by the Swedish National Register for Gynecologic Surgery.Acta 2004;83:1202-7. Gynecol
  • Scand. Chelmow D, Hennesy M, Evantash EG.Prophylactic antibiotics for non-laboring patients with intact membranes undergoing cesarean delivery: an economic analysis. Am J Obstet Gynecol. 2004;19:1661-5. Liabsuetrakul T, Islam M. Peeyananjarassri prophylaxis
  • delivery.Cochrane Database Syst Rev. 2004; 3:CD004455.
  • Antibiotic operative
  • vaginal Woodfield JC, Van Rij AM, Pettigrew RA, van der Linden AJ, Solomon C, Bolt D.Placebo-controlled, double-blind, randomized study of prophylactic antibiotics in elective abdominal 2002;52:302-6. 35.
  • Benthem PP.Antibiotic prophylaxis in clean and clean-contaminated
  • Database Syst Rev. 2004;3:CD003996.
  • Infect. Verschuur HP, de Wever WW, van ear surgery.
  • Cochrane Guaschino S, De Santo D, De Seta F. New perspectives in antibiotic prophylaxis for obstetric and gynaecological surgery. J Hosp Infect. 2002;50 Suppl A:S13-6.
  • Tanos V, Rojansky N. Prophylactic antibiotics in abdominal hysterectomy. J Am Coll Surg 1994; 179: 593-600. 38.
  • Williams MA, Kupelnick B, Klickstein A, et al. Avoiding serious infections associated with abdominal hysterectomy: a meta-analysis of antibiotic prophylaxis. Am J Obstet Gynecol 1993; 169: 1119-24. 39.
  • Grimes DA. Antibiotics at the time of induced abortion: the case for universal prophylaxis based on a meta-analysis. Obstet Gynecol 1996; 87: 884- 90.
  • Morlet N, Gatus B, Coroneo M. Patterns of perioperative prophylaxis for cataract surgery: a survey of Australian ophthalmologists. Aust N Z J Ophthalmol 1998; 26: 5-12. 41.
  • cataract operations. Mayo Clin Proc 1997; 72: 149- 59 42.
  • intracameral antibiotic prophylaxis and intraocular contamination during cataract surgery.J Cataract Refract Surg. 2004;30:2239-40. 43.
  • Yu VL, Wagener MM, Wagner RL, et al. The efficacy of perioperative antibiotic therapy on recovery following tonsillectomy in adults: randomized double-blind placebo-controlled trial. Otolaryngol Head Neck Surg 1992; 106: 137-42.
  • Colreavy MP, Nanan D, Benamer M, Donnelly M, Blaney AW, O'Dwyer TP, et al. Antibiotic prophylaxis post-tonsillectomy: is it of benefit? Int J Pediatr Otorhinolaryngol 1999; 50: 15-22.
  • Verschuur HP, de Wever WW, van Benthem PP.Antibiotic prophylaxis in clean and clean-contaminated ear surgery.Cochrane Database Syst Rev. 2004;3:CD003996.
  • Barker FG 2nd. Efficacy of prophylactic antibiotics for craniotomy: a meta-analysis. Neurosurgery 1994; 35: 484-90. 47.
  • Milner R. Efficacy of antimicrobial prophylaxis in placement of cerebrospinal fluid shunts: a meta analysis. Clin Infect Dis 1993; 17: 98-103. 48.
  • prophylaxis for cerebrospinal fluid shunts: a meta- analysis. Neurosurgery 1994; 34: 87-92.
  • Jones J. Prophylactic antibiotic use in clean neurosurgery: of potential benefit or harm to the patient? J Wound Care. 2005; 14:39-41. 50.
  • orthopaedic implant surgery - should we use a glycopeptide? J Antimicrob Chemother 1998; 41: 322-5. 51.
  • Hospital acquired infection - a framework for a national system of surveillance for the NHS in Scotland. Edinburgh: Scottish Office, 1999.
  • in Scottish Office Department of Health. Cerrahide proflaktik
  • antibiyotik kullanımı. Ankara Ü. Cerrahide Antibiyotik Proflaksi Rehberi. http://www.infection.org
  • MCW & FMLH Antibiotic guide. Suggested recommendations and guidelens for surgical İntmed.mcw.edu/drug/SurgProph.html 54.
  • Ortopedide antibiyotik proflaksisi. In: Ortopedik enfeksiyonlar. Ed: Tözün İR, Demirhan M, Özsüt H. Türk Ortopedi ve Travmatoloji Derneği, Pespektiv yayınevi 1999, s: 107-109.
  • www. Çalangu S, Göksan SB, Özsüt H. ASHP therapeutic prophylaxis in antimicrobial www.guideline.gov surgery.

Year 2008, Volume: 5 Issue: 1, 43 - 54, 01.04.2008

Ali Uzunköy

Abstract

References

  • Antibiotic prophylaxis in surgery.
  • www.sign.ac.uk/guidelines/fulltext Antibiotic prophylaxis in surgery: A national
  • http://www.guideline.gov 3.
  • guideline. KLİMİK Akılcı antibiyotik kullanımı, konferans notları 4.
  • Preclik G, Grune S, Leser HG, Lebherz J, Heldwein W, Machka K, et al. Prospective, randomised, double blind trial of prophylaxis with single dose of co-amoxiclav before percutaneous endoscopic gastrostomy. BMJ 1999; 319: 881-4.
  • Platt R, Zucker JR, Zaleznik DF, Hopkins CC, Dellinger EP, Karchmer AW, et al. Perioperative antibiotic prophylaxis and wound infection following breast surgery. J Antimicrob Chemother 1993; 31: 43-8. 6.
  • Aufenacker TJ, van Geldere D, van Mesdag T, Bossers AN, Dekker B, Scheijde E, van Nieuwenhuizen R, Hiemstra E, Maduro JH, Juttmann JW, Hofstede D, van Der Linden CT, Gouma DJ, Simons MP.The role of antibiotic prophylaxis in prevention of wound infection after Lichtenstein open mesh repair of primary inguinal hernia: a multicenter double-blind randomized controlled trial. Ann Surg 2004; 240:955-61 7.
  • Meijer WS, Schmitz PI, Jeekel J. Meta- analysis of randomised, controlled clinical trials of antibiotic prophylaxis in biliary tract surgery. Br J Surg 1990; 77: 283-90.
  • Colizza S, Rossi S, Picardi B, et al. after Surgical
  • cholecystectomy: ceftriaxone vs ceftazidime antibiotic prophylaxis. A prospective study. Chir Ital 2004; 56:397-402.
  • laparoscopic Edmiston CE, Krepel C, Kelly H, et al. Perioperative antibiotic prophylaxis in the gastric bypass patient: do we achieve therapeutic levels? Surgery. 2004;136:738-47.
  • Wasey N, Baughan J, de gara CJ. Prophylaxis in elective colorectal surgery: the cost of ignoring the evidence. Can J Surg. 2003 ; 46:279-84. 11. Hernandez
  • Pharmacokinetics and tissue penetration of pefloxacin plus metronidazole after administration as surgical prophylaxis in colorectal surgery. Int J Clin Pharmacol Ther. 2003; 41:267-74.
  • JL. Andersen BR, Kallehave FL, Andersen HK. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev. 2003;:CD001439.
  • Pessaux P, Mska S, Atalla D, et al. Risk factors for postoperative infectious complications in noncolorectal abdominal surgery: a multivariate analysis based on a prospective multicenter study of 4718 patients. Arch Surg. 2003;138:314-24. 14.
  • RA, et al. Placebo-controlled, double-blind, randomized study of prophylactic antibiotics in elective abdominal hysterectomy. J Hosp Infect. 2002;52:302-6. 15.
  • Amoxicillin/clavulanic acid versus cefotaxime for antimicrobial prophylaxis in abdominal surgery: a randomized trial. J Chemother. 2002;14:366-72.
  • Sganga G. New perspectives in antibiotic prophylaxis for intra-abdominal surgery. J Hosp Infect. 2002;50 Suppl A:S17-21. 17.
  • prophylaxis for abdominal surgery: is there a need for metronidazole?J Chemother. 2001;13:27-34. 18.
  • prophylaxis and treatment of surgical abdominal sepsis. J Chemother. 2001;13 :193-201. 19.
  • retrospective study on the efficacy of short-term perioperative prophylaxis in abdominal surgery for hernia repair in 1,254 patients. J Chemother 2000;12:34-7. 20.
  • prophylaxis with ceftriaxone in laparoscopic cholecystectomy: a 7-year clinical experience involving 3,603 patients. J Chemother. 2000;12:17- 22. U.
  • Antimicrobial Colizza S, Rossi S.
  • Antibiotic Gervino L, Cangioni G, Renzi F. A Farello GA, Cerofolini A. Antimicrobial Dellinger PE, Gross PA, Barrett TL, Krause PJ, Martone WJ, McGowan JE et al. Quality standard for antimicrobial prophylaxis in surgical procedures. Clin Infect Dis 1994; 422-7. 22.
  • Delahaye F, Chevalier P, Cerisier A, et al. Antibiotic prophylaxis for permanent pacemaker implantation: a meta-analysis. Circulation 1998; 97: 1796-801.
  • Penketh AR, Wansbrough-Jones MH, Wright E, Imrie F, Pepper JR, Parker DJ. Antibiotic prophylaxis for coronary artery bypass graft surgery. Lancet 1985; 1: 1500.
  • Ilves R, Cooper JD, Todd TR, Pearson FG. Prospective, randomised, double-blind study using prophylactic cephalothin for major, elective, general thoracic operations. J Thorac Cardiovasc Surg 1981; 81: 813-7. 25.
  • Gimferrer JM, Aznar E, et al. Antibiotic prophylaxis in non-cardiac thoracic surgery: cefazolin versus placebo. Eur J Cardiothorac Surg 1991; 5: 515-8.
  • Da Costa A, Kirkorian G, Cucherat M, Delahaye F, Chevalier P, Cerisier A, et al. Antibiotic prophylaxis for permanent pacemaker implantation: a meta-analysis. Circulation 1998; 97: 1796-801. 27.
  • Gimferrer JM, Aznar E, et al. Antibiotic prophylaxis in non-cardiac thoracic surgery: cefazolin versus placebo. Eur J Cardiothorac Surg 1991; 5: 515-8. 28.
  • I. Perioperative prophylactic cephazolin in spinal surgery. A double-blind placebo-controlled trial. J Bone Joint Surg Br 1994; 76: 99-102
  • Ritche S, Scalon N, Lewis M, Black PN. Use of a preprinted sticker to improve the prescribing of prophylactic antibiotics for hip fracture 2004;13:384-7. 30.
  • prophylaxis reduces infectious complications in caesarean delivery. Evidence-Based Medicine 1999; 4: 179. Saf Health Care Burrows RF. Review
  • antibiotic Lofgren M, Poromaa IS, Stjerndahl JH, Renstrom B. Postoperative infections and antibiotic prophylaxis for hysterectomy in Sweden: a study by the Swedish National Register for Gynecologic Surgery.Acta 2004;83:1202-7. Gynecol
  • Scand. Chelmow D, Hennesy M, Evantash EG.Prophylactic antibiotics for non-laboring patients with intact membranes undergoing cesarean delivery: an economic analysis. Am J Obstet Gynecol. 2004;19:1661-5. Liabsuetrakul T, Islam M. Peeyananjarassri prophylaxis
  • delivery.Cochrane Database Syst Rev. 2004; 3:CD004455.
  • Antibiotic operative
  • vaginal Woodfield JC, Van Rij AM, Pettigrew RA, van der Linden AJ, Solomon C, Bolt D.Placebo-controlled, double-blind, randomized study of prophylactic antibiotics in elective abdominal 2002;52:302-6. 35.
  • Benthem PP.Antibiotic prophylaxis in clean and clean-contaminated
  • Database Syst Rev. 2004;3:CD003996.
  • Infect. Verschuur HP, de Wever WW, van ear surgery.
  • Cochrane Guaschino S, De Santo D, De Seta F. New perspectives in antibiotic prophylaxis for obstetric and gynaecological surgery. J Hosp Infect. 2002;50 Suppl A:S13-6.
  • Tanos V, Rojansky N. Prophylactic antibiotics in abdominal hysterectomy. J Am Coll Surg 1994; 179: 593-600. 38.
  • Williams MA, Kupelnick B, Klickstein A, et al. Avoiding serious infections associated with abdominal hysterectomy: a meta-analysis of antibiotic prophylaxis. Am J Obstet Gynecol 1993; 169: 1119-24. 39.
  • Grimes DA. Antibiotics at the time of induced abortion: the case for universal prophylaxis based on a meta-analysis. Obstet Gynecol 1996; 87: 884- 90.
  • Morlet N, Gatus B, Coroneo M. Patterns of perioperative prophylaxis for cataract surgery: a survey of Australian ophthalmologists. Aust N Z J Ophthalmol 1998; 26: 5-12. 41.
  • cataract operations. Mayo Clin Proc 1997; 72: 149- 59 42.
  • intracameral antibiotic prophylaxis and intraocular contamination during cataract surgery.J Cataract Refract Surg. 2004;30:2239-40. 43.
  • Yu VL, Wagener MM, Wagner RL, et al. The efficacy of perioperative antibiotic therapy on recovery following tonsillectomy in adults: randomized double-blind placebo-controlled trial. Otolaryngol Head Neck Surg 1992; 106: 137-42.
  • Colreavy MP, Nanan D, Benamer M, Donnelly M, Blaney AW, O'Dwyer TP, et al. Antibiotic prophylaxis post-tonsillectomy: is it of benefit? Int J Pediatr Otorhinolaryngol 1999; 50: 15-22.
  • Verschuur HP, de Wever WW, van Benthem PP.Antibiotic prophylaxis in clean and clean-contaminated ear surgery.Cochrane Database Syst Rev. 2004;3:CD003996.
  • Barker FG 2nd. Efficacy of prophylactic antibiotics for craniotomy: a meta-analysis. Neurosurgery 1994; 35: 484-90. 47.
  • Milner R. Efficacy of antimicrobial prophylaxis in placement of cerebrospinal fluid shunts: a meta analysis. Clin Infect Dis 1993; 17: 98-103. 48.
  • prophylaxis for cerebrospinal fluid shunts: a meta- analysis. Neurosurgery 1994; 34: 87-92.
  • Jones J. Prophylactic antibiotic use in clean neurosurgery: of potential benefit or harm to the patient? J Wound Care. 2005; 14:39-41. 50.
  • orthopaedic implant surgery - should we use a glycopeptide? J Antimicrob Chemother 1998; 41: 322-5. 51.
  • Hospital acquired infection - a framework for a national system of surveillance for the NHS in Scotland. Edinburgh: Scottish Office, 1999.
  • in Scottish Office Department of Health. Cerrahide proflaktik
  • antibiyotik kullanımı. Ankara Ü. Cerrahide Antibiyotik Proflaksi Rehberi. http://www.infection.org
  • MCW & FMLH Antibiotic guide. Suggested recommendations and guidelens for surgical İntmed.mcw.edu/drug/SurgProph.html 54.
  • Ortopedide antibiyotik proflaksisi. In: Ortopedik enfeksiyonlar. Ed: Tözün İR, Demirhan M, Özsüt H. Türk Ortopedi ve Travmatoloji Derneği, Pespektiv yayınevi 1999, s: 107-109.
  • www. Çalangu S, Göksan SB, Özsüt H. ASHP therapeutic prophylaxis in antimicrobial www.guideline.gov surgery.
There are 62 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Ali Uzunköy This is me

Publication Date April 1, 2008
Published in Issue Year 2008 Volume: 5 Issue: 1

Cite

Vancouver Uzunköy A. Cerrahi Branşlara Göre Yapılan Ameliyatlarda Antibiyotik Proflaksi Klavuzu. Harran Üniversitesi Tıp Fakültesi Dergisi. 2008;5(1):43-54.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty