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Akut böbrek yetmezliği

Year 2004, Volume: 1 Issue: 3, 48 - 63, 01.04.2004

Abstract

Akut böbrek yetmezliği ABY glomerüler filtrasyon hızında GFR gelişen azalma ve bunun sonucunda kan üre azotu, kreatinin ve diğer üremik toksinlerin vücutta birikimini ifade eden bir durumdur. GFR’deki düşüşün aylar hatta yıllar içerisinde geliştiği kronik böbrek yetmezliğinin aksine, akut böbrek yetmezliğindeki GFR düşüşü daha hızlıdır ve günler ile haftalar içeriside gelişir 1 . GFR’deki azalma önceden herhangi bir renal hasarı olmayan bireylerde oluşabileceği gibi, önceden kronik bir renal bozukluğu olan bireylerde de akut ekzazarbasyon şeklinde ortaya çıkabilmektedir. ABY’nde idrar miktarı değişkendir. Sıklıkla oligüri günde 400 ml’den daha az idrar ve anüri günde 100 ml’den daha az idrar ile birliktedir, ancak nadiren de olsa idrar miktarında azalma olmayabilmektedir nonoligürik ABY . Total anüri nadirdir ve bu durumda akut kortikal nekrozdan şüphelenilmelidir.

References

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  • Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996;334:1448-1460.
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  • Finn WF. Recovery from acute renal failure. In: Lazarus JM, Brenner BM, eds. Acute renal failure. 3d ed. New York: Churchill Livingstone, 1993:553-596.
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  • Nolan CR, Anderson RJ. Hospital- acquired acute renal failure, J Am Soc Nephrol 1998;9:710-718.
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  • detectable 16-Martinez-Maldonado M, Kumjian DA. Acute renal failure due to urinary tract obstruction. 1990;74:919-932. Clin North
  • Am 17-Blantz RC. Pathophysiology of pre- renal azotemia. Kidney Int 1998;53:512- 523.
  • Denton MD, Chertow GM, Brady HR. “Renal-dose” dopamine for the treatment of acute renal failure: Scientific rationale, experimental studies and clinical trials. Kidney Int 1996;50:4-14.
  • Burton CJ, Tomson CR. Can the use of low dose dopamine for treatment of acute renal failure be justified? Postgrad Med J 1999;75:269-274.
  • Kellum JA, Decker JM. Use of dopamine in acute renal failure: A meta- analysis. Crit Care Med 2001;29:1526- 1531.
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  • R. 23-Mehta RL, Letteri JM. Current status of renal replacement therapy for acute renal failure. A survey of US nephrologists. Am J Nephrology 1999;19:377-382.
  • Kellum JA. Use of diuretics in the acute care setting. Kidney Int Suppl 1998;66: 81-86.
  • Kleinknecht D, Ganeval D, Gonzales- Duque LA, Fermanian J. Furosemide in acute oliguric renal failure. A controlled trial. Nephron 1976;17: 51-58.
  • Brown CB, Ogg CS, Cameron JS. High dose furosemide in acute renal failure: A controlled trial. Clin Nephrol 1981;15: 90-96.
  • Shilliday IR, Quinn KJ, Allison ME. Loop diuretics in the management of acute renal failure: A prospective, double-blind, placebo-controlled
  • Nephrol Dial Transplant 1997;12:2592- 2596. randomized study. Acute Renal Failure. In: Brenner BM, eds. Brenner & Rector's The Kidney, 7th ed. W.B. Saunders, 2004; 1215-1270.
  • Bataller R, Sort P, Gines P, Arroyo V. Hepatorenal pathophysio-logy, clinical features and management. Kidney Int 1998;66:47–53.
  • Gines P, Sort P. Pathophysiology of renal dysfunction in cirrhosis. Digestion 1998;59:11–15.
  • Gines P, Arroyo V: Hepatorenal syndrome. 1999;10:1833–1839. Soc
  • Nephrol 38- Sort P, Navasa M, Arroyo V, Aldeguer X, Planas R, Ruiz-del-Arbol L, Castells L, Vargas V, Soriano G, Guevara M, Gines P, Rodes J. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med 1999;341:403– 409.
  • Hadengue A, Gadano A, Moreau R, Giostra E, Durand F, Valla D, Erlinger S, Lebrec D. Beneficial effects of the 2-day administration of terlipressin in patients with cirrhosis and hepatorenal syndrome. J Hepatol 1998;29:565–570.
  • Teschan PE, Baxter CR, O'brien TF, Freyhof JN, Hall WH. Prophylactic hemodialysis in the treatment of acute renal 1960;53:992-1016. Intern
  • Med 41-Fischer RP, Griffen WO Jr, Reiser M, Clark DS. Early dialysis in the treatment of acute renal failure. Surg Gynecol Obstet 1966;123:1019–1023.
  • Mault JR, Dechert RE, Lees P, Swartz RD, Port FK, Bartlett RH. Continuous arteriovenous filtra-tion: An effective treatment for surgical acute renal failure. Surgery 1987;101:478–484.
Year 2004, Volume: 1 Issue: 3, 48 - 63, 01.04.2004

Abstract

References

  • Abernethy VE, Lieberthal W. Acute renal failure in the critically ill patient. Crit Care Clin 2002;18:203-222.
  • Albright RC. Acute renal failure: a practical 2001;76:67-74. Mayo Clin
  • Proc 3-Hou SH, Bushinsky DA, Wish JB, Cohen JJ, Harrington JT. Hospital- acquired renal insufficiency: a prospective study. Am J Med 1983;74:243-248.
  • Brady HR, Singer GG. Acute renal failure. Lancet 1995;346:1533-1540.
  • Liano F, Junco E, Pascual J, Madero R, Verde E. The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study Group. Kidney Int Suppl 1998;66:16-24.
  • Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996;334:1448-1460.
  • Feest TG, Round A, Hamad S. Incidence of severe acute renal failure in adults: results of a community based study. BMJ 1993;306:481-483.
  • Finn WF. Recovery from acute renal failure. In: Lazarus JM, Brenner BM, eds. Acute renal failure. 3d ed. New York: Churchill Livingstone, 1993:553-596.
  • Brady HR, Singer GG. Acute renal failure. Lancet 1995;346:1533-1540.
  • Nolan CR, Anderson RJ. Hospital- acquired acute renal failure, J Am Soc Nephrol 1998;9:710-718.
  • Agrawal M, Swartz R. Acute renal failure. Am Fam Physician. 2000;61:2077- 2088. Erratum in: Am Fam Physician 2001;63:445.
  • Faber MD, Kupin WL, Krishna GG, Narins RG. The differential diagnosis of acute renal failure. In: Lazarus JM, Brenner BM, eds. Acute renal failure. 3d ed. New York: Churchill Livingstone, 1993:133-192.
  • Hricik DE, Chung-Park M, sedor JR. Glomerulonephritis. N Engl J Med 1998;339:888-99.
  • Abuelo JG. Diagnosing vascular causes of 1995;123:601-14. Ann Intern Med 15-Mayo RR, Swartz RD. Redefining the incidence atheroembolism. Am J Med 1996;100:524- 529.
  • detectable 16-Martinez-Maldonado M, Kumjian DA. Acute renal failure due to urinary tract obstruction. 1990;74:919-932. Clin North
  • Am 17-Blantz RC. Pathophysiology of pre- renal azotemia. Kidney Int 1998;53:512- 523.
  • Denton MD, Chertow GM, Brady HR. “Renal-dose” dopamine for the treatment of acute renal failure: Scientific rationale, experimental studies and clinical trials. Kidney Int 1996;50:4-14.
  • Burton CJ, Tomson CR. Can the use of low dose dopamine for treatment of acute renal failure be justified? Postgrad Med J 1999;75:269-274.
  • Kellum JA, Decker JM. Use of dopamine in acute renal failure: A meta- analysis. Crit Care Med 2001;29:1526- 1531.
  • Australian and New Zealand Intensive Care Society Clinical Trials Group. Low- dose dopamine in patients with early renal dysfunction: randomised trial. Lancet 2000;356:2139- 2143.
  • Pathophysiologic features and prevention of human and experimental acute tubular necrosis. J Am Soc Nephrol 2001;12: 20- 32. Vanholder
  • R. 23-Mehta RL, Letteri JM. Current status of renal replacement therapy for acute renal failure. A survey of US nephrologists. Am J Nephrology 1999;19:377-382.
  • Kellum JA. Use of diuretics in the acute care setting. Kidney Int Suppl 1998;66: 81-86.
  • Kleinknecht D, Ganeval D, Gonzales- Duque LA, Fermanian J. Furosemide in acute oliguric renal failure. A controlled trial. Nephron 1976;17: 51-58.
  • Brown CB, Ogg CS, Cameron JS. High dose furosemide in acute renal failure: A controlled trial. Clin Nephrol 1981;15: 90-96.
  • Shilliday IR, Quinn KJ, Allison ME. Loop diuretics in the management of acute renal failure: A prospective, double-blind, placebo-controlled
  • Nephrol Dial Transplant 1997;12:2592- 2596. randomized study. Acute Renal Failure. In: Brenner BM, eds. Brenner & Rector's The Kidney, 7th ed. W.B. Saunders, 2004; 1215-1270.
  • Bataller R, Sort P, Gines P, Arroyo V. Hepatorenal pathophysio-logy, clinical features and management. Kidney Int 1998;66:47–53.
  • Gines P, Sort P. Pathophysiology of renal dysfunction in cirrhosis. Digestion 1998;59:11–15.
  • Gines P, Arroyo V: Hepatorenal syndrome. 1999;10:1833–1839. Soc
  • Nephrol 38- Sort P, Navasa M, Arroyo V, Aldeguer X, Planas R, Ruiz-del-Arbol L, Castells L, Vargas V, Soriano G, Guevara M, Gines P, Rodes J. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med 1999;341:403– 409.
  • Hadengue A, Gadano A, Moreau R, Giostra E, Durand F, Valla D, Erlinger S, Lebrec D. Beneficial effects of the 2-day administration of terlipressin in patients with cirrhosis and hepatorenal syndrome. J Hepatol 1998;29:565–570.
  • Teschan PE, Baxter CR, O'brien TF, Freyhof JN, Hall WH. Prophylactic hemodialysis in the treatment of acute renal 1960;53:992-1016. Intern
  • Med 41-Fischer RP, Griffen WO Jr, Reiser M, Clark DS. Early dialysis in the treatment of acute renal failure. Surg Gynecol Obstet 1966;123:1019–1023.
  • Mault JR, Dechert RE, Lees P, Swartz RD, Port FK, Bartlett RH. Continuous arteriovenous filtra-tion: An effective treatment for surgical acute renal failure. Surgery 1987;101:478–484.
There are 35 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Mehmet Horoz This is me

Özden Özgür This is me

Publication Date April 1, 2004
Published in Issue Year 2004 Volume: 1 Issue: 3

Cite

Vancouver Horoz M, Özgür Ö. Akut böbrek yetmezliği. Harran Üniversitesi Tıp Fakültesi Dergisi. 2004;1(3):48-63.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty