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Çocuk Acil Polikliniğine Kanama Şikayeti ile Başvuran Hastaların Değerlendirilmesi: Tek Merkez Deneyimi

Year 2024, Volume: 21 Issue: 1, 26 - 30, 29.04.2024
https://doi.org/10.35440/hutfd.1374760

Abstract

Amaç: Bu çalışmada, Çocuk Acil polikliniğimize kanama öyküsü ile başvuran hastaların demografik özelliklerinin ve etiyolojik nedenlerinin değerlendirilmesi amaçlandı.
Gereç ve yöntem: XXX Üniversitesi Çocuk Hastanesi Acil Polikliniğine Ocak 2010-Aralık 2012 tarihleri arasında kanama öyküsü ile başvuran 331 hastanın dosyası retrospektif incelendi. Çalışmaya alınan hastaların yaş, başvuru şikâyetleri, muayene bulguları, cinsiyet, başvuru zamanı, başvuru mevsimi ve kanama etiyolojisi kaydedildi.
Bulgular: Hasta grubu 133’ü kız, 198’i erkek olmak üzere toplam 331 hastadan oluşmaktaydı. Yaş aralığı 1-192 ay arasında idi. Çocuk acil polikliniğine başvuran hastalarda en sık burun ve ağız içi kanama tespit edilirken, en az sıklıkta enfeksiyöz trombositopeni saptandı. Diğer etiyolojik nedenler; immün trombositopenik purpura, gastrointestinal sistem kanamaları, faktör eksikliği, Henoch Schonlein Purpurası, Glanzmann trombastenisiydi. Kanama etiyolojisi ile cinsiyet arasında istatistiksel bir anlamlılık olup (p<0,05), erkeklerde kızlara göre daha sık olduğu gözlendi. Hastaların %40,8’lik bir kısmında kanama (ağız, burun), %20,8’lik bir kısmında ise ekimoz muayene bulgusuna rastlandı. Ayrıca purpura ile gelen olgularda en sık etiyolojik neden Henoch Schonlein purpurası, peteşi ve ekimoz ile gelenlerde immün trombositopenik purpura, hemartroz ve hematom ile gelenlerde faktör eksikliği ve solukluk ile gelenlerde ise gastrointestinal sistem kanamaları görüldü. Kanama etiyolojisi ile muayene bulguları arasında istatistiksel bir anlamlılık saptandı. Özellikle Glanzmann trombastenisi, Henoch Schonlein purpurası ve enfeksiyoz trombositopeni tanısı konulan hastalarda ay ve/veya mevsimin hastalıklar üzerine etkisi gözlendi.
Sonuç: Çocuk Acil polikliniğine kanama öyküsü ile başvuranlarda acil tetkik ve tedavi gerektiren klinik durumların tespiti açısından, doğru tanıya hızlı bir şekilde ulaşmada demografik özelliklerinin ve etiyolojilerinin tespit edilmesi önemlidir. Bunun sonucunda riskli hastaların erken fark edilmesi ve tedavi planlanması hem morbiditeyi hem de mortaliteyi azaltmada yol gösterici olabilir.

References

  • 1. Hussein HK, Nicolson P, Fordwor K, Lowe GC. Mild bleeding disorders: what every clinician should know. Br J Hosp Med 2017;78(12):684-710.
  • 2. Öztürk MA, Güneş T. Acil hastanın özellikleri ve acil hastaya yaklaşım. Turkiye Klinikleri J Ped Spec Top 2004;2(6):519-28.
  • 3. Allen GA, Glader B. (2002). Approach to the bleeding child. Pediatr Clin North Am 2002;49(6):1239-56.
  • 4. Viljoen J. Epistaxis in children: Approach and management. Contin Med Educ 2003;21(11):664-669.
  • 5. Stadler RR, Kindler RM, Landis BN, Vogel NI, Holzmann D, Soyka MB. (2018). Emergency consultation for epistaxis: A bad predictor for overall health?. Auris Nasus Larynx 2018;45(3):482-6.
  • 6. Adedeji TO, Bande SA. Epistaxis and its Management in a Tertiary Health Facility in Nigeria:A need for thorough Evalu-ation. West Afr J Med 2014;33(3):195-200.
  • 7. Akyüz FÇ, Kelekçi S, Söker M, Karabel M, Şen V, Üzel VH ve ark. İmmün Trombositopenik Purpura Olgularımızın Değer-lendirilmesi: Tek Merkez Deneyimi. J Turgut Ozal Med Cen 2013;20(3):246-51.
  • 8. D'Orazio JA, Neely J, Farhoudi N. İTP in children: pathophysi-ology and current treatment approaches. J Pediatr Hema-tol/Oncol 2013;35(1):1-13.
  • 9. Koç I. Prevalence and sociodemographic correlates of con-sanguineous marriages in Turkey. J Biosoc Sci 2008;40:137-48.
  • 10. Şalcıoğlu Z, Bayram C, Şen H, Ersoy G, Aydoğan G, Akçay A et al. Congenital Factor Deficiencies in Children: A Report of a Single-Center Experience. Clin Appl Thromb Hemost 2018;24(6):901-7.
  • 11. Ece A, Yolbaş İ, Balık H, Kocamaz H, Yel S, Uluca Ü ve ark. Çocuklarda Henoch- Schönlein purpurası: 214 hastanın de-ğerlendirilmesi. J Clin Exp Invest 2012;3(1):91-5.
  • 12. Gedalia A. Henoch-Schönlein purpura. Curr Rheumatol Rep 2004;6(3):195-202.
  • 13. Trapani S, Micheli A, Grisolia F, Resti M, Chiappini E, Falcini F et al. HenochSchönlein purpura in childhood: epidemiologi-cal and clinical analysis of 150 cases over a 5-year period and review of literature. Semin Arthritis Rheum 2005;35(3):143-53.
  • 14. Wilkinson A. Early recognition and treatment of Henoch-Schönlein purpura in children. Nurs Child Young People 2019;31(5):36-40.
  • 15. Botero JP, Lee K, Branchford BR, Bray PF, Freson K, Lambert MP et al. Glanzmann thrombasthenia: genetic basis and cli-nical correlates. Haematologica 2020;105(4):888-94.
  • 16. Pant C, Sankararaman S, Deshpande A, Olyaee M, Anderson MP, Sferra TJ. (2014). Gastrointestinal bleeding in hospitali-zed children in the United States. Curr Med Res Opin 2014;30(6):1065-9.
  • 17. Gerçeker E, Kasırga E, Doğan G, Soysal B. (2021). Üst ve alt gastrointestinal sistem endoskopisi yapılan çocuklarda gast-rointestinal kanamalarının retrospektif değerlendirilmesi. Sakarya Tıp Dergisi 2021;11(1):53-60.
  • 18. Güngör T, Bilir ÖA, Çulha VK, Güngör A, Kara A, Azık FM et al. Retrospective evaluation of children with immune throm-bocytopenic purpura and factors contributing to chronicity. Pediatr Neonatol 2019;60(4):411-6.
  • 19. Choudhary S, Kumar D, K Bohra G, Gupta A, Meena DS, Rat-hore RS et al. Clinical Evaluation of Febrile Thrombocytope-nia in Western Rajasthan- a Hospital-based Study. Infect Di-sord Drug Targets 2022;20(5):718-723.
  • 20. Oni L, Sampath S. Childhood IgA Vasculitis (Henoch Schon-lein Purpura)-Advances and Knowledge Gaps. Front Pediatr 2019;27(7):257.

Evaluation of Patients Applied to the Children’s Hospital Emergency Polyclin-ic with Complaint of Bleeding: A Single Center Experience

Year 2024, Volume: 21 Issue: 1, 26 - 30, 29.04.2024
https://doi.org/10.35440/hutfd.1374760

Abstract

Background: In this study, it was aimed to evaluate the demographic characteristics and etiologic causes of patients admitted to our Pediatric Emergency Clinic with a history of bleeding.
Materials and methods: The files of 331 patients admitted to the emergency outpatient clinic of XXX University Children's Hospital between January 2010 and December 2012 with a history of bleeding were retrospectively analyzed. Age, presenting complaints, examination findings, gender, time of presentation, season of presentation and etiology of bleeding were recorded.
Results: The patient group in the study consisted of a total of 331 patients, of whom 133 were female and 198 were male. The age range of the patients in the study was between 1-92 months. Patients applied to the pediatric emergency outpatient clinic were most frequently applied due to nasal and oral bleeding, and least frequently because of infectious thrombocytopenia. Other etiologic causes were immune thrombocytopenic purpura, gastrointestinal bleeding, factor deficiency, Henoch Schonlein Purpura and Glanzmann thrombasthenia. There was a statistical significance between the etiology of bleeding and gender (p<0,05), and it was observed that it was more common in boys than girls. Considering the examination findings, bleeding (mouth, nose) was found in 40.8% of the patients, and ecchymosis was found in 20.8% of the patients. In addition, the most common etiologic cause was immune thrombocytopenic purpura in patients presenting with petechiae and ecchymosis, Henoch Schonlein purpura in patients presenting with purpura, factor deficiency in patients presenting with hemarthrosis and hematoma, and gastrointestinal system bleeding in patients presenting with pallor. A statistical significance was found between the examination findings and the bleeding etiology. It was determined that the month and/or season had a significant effect on the diseases, especially in patients diagnosed with infectious tombocytopenia, Glanzmann’s thrombasthenia, and Henoch Schonlein purpura.
Conclusions: It is important to determine the demographic characteristics and etiologies of patients presenting to the Pediatric Emergency Outpatient Clinic with a history of bleeding in order to determine the clinical conditions requiring urgent examination and treatment, and to reach the correct diagnosis quickly. As a result, early recognition of risky patients and treatment planning may be guiding in reducing both morbidity and mortality.

References

  • 1. Hussein HK, Nicolson P, Fordwor K, Lowe GC. Mild bleeding disorders: what every clinician should know. Br J Hosp Med 2017;78(12):684-710.
  • 2. Öztürk MA, Güneş T. Acil hastanın özellikleri ve acil hastaya yaklaşım. Turkiye Klinikleri J Ped Spec Top 2004;2(6):519-28.
  • 3. Allen GA, Glader B. (2002). Approach to the bleeding child. Pediatr Clin North Am 2002;49(6):1239-56.
  • 4. Viljoen J. Epistaxis in children: Approach and management. Contin Med Educ 2003;21(11):664-669.
  • 5. Stadler RR, Kindler RM, Landis BN, Vogel NI, Holzmann D, Soyka MB. (2018). Emergency consultation for epistaxis: A bad predictor for overall health?. Auris Nasus Larynx 2018;45(3):482-6.
  • 6. Adedeji TO, Bande SA. Epistaxis and its Management in a Tertiary Health Facility in Nigeria:A need for thorough Evalu-ation. West Afr J Med 2014;33(3):195-200.
  • 7. Akyüz FÇ, Kelekçi S, Söker M, Karabel M, Şen V, Üzel VH ve ark. İmmün Trombositopenik Purpura Olgularımızın Değer-lendirilmesi: Tek Merkez Deneyimi. J Turgut Ozal Med Cen 2013;20(3):246-51.
  • 8. D'Orazio JA, Neely J, Farhoudi N. İTP in children: pathophysi-ology and current treatment approaches. J Pediatr Hema-tol/Oncol 2013;35(1):1-13.
  • 9. Koç I. Prevalence and sociodemographic correlates of con-sanguineous marriages in Turkey. J Biosoc Sci 2008;40:137-48.
  • 10. Şalcıoğlu Z, Bayram C, Şen H, Ersoy G, Aydoğan G, Akçay A et al. Congenital Factor Deficiencies in Children: A Report of a Single-Center Experience. Clin Appl Thromb Hemost 2018;24(6):901-7.
  • 11. Ece A, Yolbaş İ, Balık H, Kocamaz H, Yel S, Uluca Ü ve ark. Çocuklarda Henoch- Schönlein purpurası: 214 hastanın de-ğerlendirilmesi. J Clin Exp Invest 2012;3(1):91-5.
  • 12. Gedalia A. Henoch-Schönlein purpura. Curr Rheumatol Rep 2004;6(3):195-202.
  • 13. Trapani S, Micheli A, Grisolia F, Resti M, Chiappini E, Falcini F et al. HenochSchönlein purpura in childhood: epidemiologi-cal and clinical analysis of 150 cases over a 5-year period and review of literature. Semin Arthritis Rheum 2005;35(3):143-53.
  • 14. Wilkinson A. Early recognition and treatment of Henoch-Schönlein purpura in children. Nurs Child Young People 2019;31(5):36-40.
  • 15. Botero JP, Lee K, Branchford BR, Bray PF, Freson K, Lambert MP et al. Glanzmann thrombasthenia: genetic basis and cli-nical correlates. Haematologica 2020;105(4):888-94.
  • 16. Pant C, Sankararaman S, Deshpande A, Olyaee M, Anderson MP, Sferra TJ. (2014). Gastrointestinal bleeding in hospitali-zed children in the United States. Curr Med Res Opin 2014;30(6):1065-9.
  • 17. Gerçeker E, Kasırga E, Doğan G, Soysal B. (2021). Üst ve alt gastrointestinal sistem endoskopisi yapılan çocuklarda gast-rointestinal kanamalarının retrospektif değerlendirilmesi. Sakarya Tıp Dergisi 2021;11(1):53-60.
  • 18. Güngör T, Bilir ÖA, Çulha VK, Güngör A, Kara A, Azık FM et al. Retrospective evaluation of children with immune throm-bocytopenic purpura and factors contributing to chronicity. Pediatr Neonatol 2019;60(4):411-6.
  • 19. Choudhary S, Kumar D, K Bohra G, Gupta A, Meena DS, Rat-hore RS et al. Clinical Evaluation of Febrile Thrombocytope-nia in Western Rajasthan- a Hospital-based Study. Infect Di-sord Drug Targets 2022;20(5):718-723.
  • 20. Oni L, Sampath S. Childhood IgA Vasculitis (Henoch Schon-lein Purpura)-Advances and Knowledge Gaps. Front Pediatr 2019;27(7):257.
There are 20 citations in total.

Details

Primary Language Turkish
Subjects Pediatric Emergency
Journal Section Research Article
Authors

Rojan İpek 0000-0002-5636-0262

Meki Bilici 0000-0001-8316-7102

Ayfer Gözü Pirinççioğlu 0000-0002-2524-2124

Yusuf Kenan Haspolat 0000-0003-1930-9721

Early Pub Date March 18, 2024
Publication Date April 29, 2024
Submission Date October 11, 2023
Acceptance Date February 20, 2024
Published in Issue Year 2024 Volume: 21 Issue: 1

Cite

Vancouver İpek R, Bilici M, Pirinççioğlu AG, Haspolat YK. Çocuk Acil Polikliniğine Kanama Şikayeti ile Başvuran Hastaların Değerlendirilmesi: Tek Merkez Deneyimi. Harran Üniversitesi Tıp Fakültesi Dergisi. 2024;21(1):26-30.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty