A Glance at the Role of Sheep in the Transmission and Surveillance of Foot-and-Mouth Disease

Year 2026, Volume: 15 Issue: 1, 29 - 38, 27.03.2026

Cansu Yıldırım Deveci , Feray Alkan

https://doi.org/10.31196/huvfd.1860001

https://izlik.org/JA45XR64AR

Abstract

The study presented serological evidence of exposure to foot-and-mouth disease virus (FMDV) serotype O in sheep from two herds, named Farm A and Farm G, following the
detection of antibodies against non-structural proteins (NSPs), which serve as markers of viral exposure. The herds included unvaccinated animals with no history of foot-andmouth disease (FMD), as reported by their owners. Seropositivity was determined to be 59.09% and 6.25% for Farm A and Farm G, respectively. These findings are discussed with respect to subclinical FMDV infection in sheep and its potential implications for cattle, informed by previous reports.

Keywords

Antibody , ELISA , Foot-and-Mouth disease , Neutralization , Sheep , Vaccine.

Ethical Statement

This study was conducted in accordance with ethical principles and regulations, using materials obtained with the approval of the Foot-and-Mouth Disease (FMD) Institute Ethics Committee (decision no: 2023/07, dated: 13.07.2023).

Project Number

1

Thanks

This study is derived from the doctoral thesis of Cansu YILDIRIM DEVECİ, a doctoral student in the Department of Virology at Ankara University Faculty of Veterinary Medicine. We would like to thank the two private livestock farms in Ankara that provided the samples used in this study, the Foot-and-Mouth Disease Institute for enabling the relevant tests, and the Department of Virology at Ankara University Faculty of Veterinary Medicine for their support in conducting this thesis.

Koyunların Şap Hastalığının Bulaşması ve Surveyansındaki Rolüne Genel Bir Bakış

https://izlik.org/JA45XR64AR

Abstract

Bu çalışma, viral maruziyetin belirteçleri olarak işlev gören yapısal olmayan proteinlere (NSP'ler) karşı antikorların saptanmasının ardından, A ve G çiftlikleri olarak adlandırılan iki sürüdeki koyunlarda şap hastalığı virüsü (FMDV) serotip O'ya maruz kalmaya dair serolojik kanıtlar sunmuştur. Sürülerde, sahipleri tarafından bildirildiği üzere, şap hastalığı (FMD) öyküsü olmayan aşılanmamış hayvanlar yer almıştır. Seropozitiflik oranı A çiftliği için %59,09 ve G çiftliği için %6,25 olarak belirlenmiştir. Bu bulgular, koyunlarda subklinik FMDV enfeksiyonu ve bunun sığırlar için potansiyel etkileri açısından, önceki raporlardan yola çıkarak tartışılmıştır.

Keywords

Aşı , Koyun , Nötralizasyon , Şap hastalığı , ELISA , Antikor

Ethical Statement

Bu çalışma, etik ilke ve mevzuatlara uygun olarak, Türkiye Cumhuriyeti Tarım ve Orman Bakanlığı Hayvancılık Genel Müdürlüğü bünyesinde yer alan Şap Enstitüsü (FMD) Etik Kurulu’nun onayı ile temin edilen materyaller kullanılarak yürütülmüştür.

Project Number

1

Thanks

Bu çalışma, Ankara Üniversitesi Veteriner Fakültesi Viroloji Anabilim Dalı'nda doktora öğrencisi olan Cansu YILDIRIM DEVECİ'nin doktora tezinden üretilmiştir. Bu çalışmada kullanılan örneklerin alındığı Ankara'da bulunan iki özel hayvancılık işletmesine, ilgili testlerin yapılmasını sağlayan Şap Enstitüsü Müdürlüğü'ne ve bu tezin yürütülmesinde destek veren Ankara Üniversitesi Veteriner Fakültesi Viroloji Anabilim Dalı'na teşekkür ederiz.

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