Ovariohisterektomi Geçiren Köpeklerde Ovaryum ve Uterustaki Patolojik Lezyonların Değerlendirilmesi

Abstract

Bu çalışmanın amacı, XXXXX Üniversitesi Veteriner Fakültesi XXXXX Anabilim Dalı’nda rutin ovariohisterektomi uygulanan dişi köpeklerden elde edilen ovaryum ve uterus dokularında gözlenen patolojik lezyonların türlerini, sıklıklarını ve dağılımlarını değerlendirmektir. Farklı ırk ve yaşlardaki toplam 67 dişi köpeğe ait ovaryum ve uterus doku örneği incelendi. Doku örnekleri %10’luk formaldehit solüsyonunda tespit edildi, rutin histolojik işlemlerden geçirilerek parafin bloklara gömüldü, 4–5 µm kalınlığında kesitler alındı ve ışık mikroskobunda histopatolojik inceleme amacıyla Hematoksilen ve Eozin ile boyandı. Ovaryum dokularının %23,88’inde patolojik lezyonlar saptandı. En yaygın ovaryal lezyonlar foliküler kist (%7,46) ve luteal kist (%5,97) olup, bunları paraovaryan kist (%4,48) ve polikistik over (%2,98) izledi. Ooforitis ve ovaryum kalıntı sendromu ise ayrı ayrı %1,49 oranında belirlendi. Uterus dokularında piyometra %8,95 oranında saptanırken, kistik endometriyal hiperplazi ile birlikte görülen piyometra %11,94 oranında belirlendi. Metritis ve serozal kistler ise %1,49 oranında gözlendi. Bu bulgular, rutin ovariohisterektomi materyallerinde subklinik reprodüktif patolojilerin dikkate değer bir oranda bulunduğunu göstermektedir. Histopatolojik inceleme, klinik olarak belirti vermeyen lezyonların saptanmasında kritik bir rol oynamakta ve reprodüktif sağlığın değerlendirilmesine önemli katkı sağlamaktadır.

Keywords

• Histopatoloji
• Köpek
• Ovaryal Patoloji
• Ovariohisterektomi
• Uterin Patoloji

Supporting Institution

Bu çalışma herhangi bir kurum veya proje tarafından desteklenmemiştir.

Project Number

Not applicable.

Ethical Statement

Bu çalışma, Burdur Mehmet Akif Ersoy Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu tarafından onaylanmıştır (Etik Kurul Karar No: 1220, Tarih: 29.11.2023). Ayrıca, yazarlar Araştırma ve Yayın Etiği kurallarına uyulduğunu beyan etmişlerdir.

Thanks

Uygulanamaz.

Evaluation of Ovarian and Uterine Pathological Lesions in Dogs Undergoing Ovariohysterectomy

Abstract

This study aimed to evaluate the types, frequency, and distribution of pathological lesions observed in the ovarian and uterine tissues of female dogs subjected to ovariohysterectomy at the Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University. A total of 67 ovarian and uterine tissue samples obtained from bitches of different breeds and ages were examined. The samples were fixed in 10% formaldehyde, routinely processed, embedded in paraffin blocks, sectioned at 4-5 µm, and stained with Hematoxylin and Eosin for histopathological examination under a light microscope. Pathological lesions were detected in 23.88% of ovarian tissues. The most common ovarian lesions were follicular cysts (n=5; 7.46%) and luteal cysts (n=4; 5.97%), followed by paraovarian cysts (n=3; 4.48%) and polycystic ovaries (n=2; 2.98%). Oophoritis and ovarian remnant syndrome were each identified at a rate of (n=1;1.49%). In uterine tissues, pyometra was detected at a rate of (n=6; 8.95%), while pyometra associated with cystic endometrial hyperplasia was identified at a rate of (n=8; 11.94%). Metritis and serosal cysts were observed at a rate of (n=1; 1.49%). These findings indicate that reproductive pathological lesions, including clinically unapparent lesions, may be present at a considerable rate in ovariohysterectomy materials. Histopathological examination plays a crucial role in detecting clinically unapparent lesions and contributes significantly to the evaluation of reproductive health.

Keywords

• Dog
• histopathology
• ovarian pathology
• ovariohysterectomy
• uterine pathology

Supporting Institution

This study was not supported by any institution or project.

Project Number

Not applicable.

Ethical Statement

This study was approved by the Burdur Mehmet Akif Ersoy University Animal Experiments Local Ethics Committee (ethics committee decision no: 1220, date: 29.11.2023). In addition, the authors declared that Research and Publication Ethical rules were followed.

Thanks

Not applicable.

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