İneklerde Tohumlama Sonrası Uygulanan Lesirelin Asetat (GnRH Analogu)'ın Gebelik Oranları Üzerine Etkisi

Abstract

Bu çalışmada, ineklere suni tohumlama sonrası farklı yollardan lesirelin asetat enjeksiyonlarının gebelik oranları üzerindeki etkisi araştırıldı. Materyal olarak postpartum 50-120. günler arasında kendiliğinden östrüse gelen, düzenli aralıklarla seksüel siklus gösteren ve bu süreçte herhangi bir klinik bozukluk göstermeyen farklı ırk ve yaştan 180 inek kullanıldı. Çalışmada kullanılan inekler rastgele 4 gruba ayrıldı. A grubunda bulunan (n= 50) hayvanlara suni tohumlamadan hemen sonra 50 µg lesirelin asetat, B grubu (n=40), hayvanlara 2 ml serum fizyolojik üst epidural boşluğa uygulandı. C grubu (n=50), hayvanlara suni tohumlamadan hemen sonra kas içi 50 µg lesirelin asetat, D grubuna (n=40), 2 ml serum fizyolojik gene kas içi olarak enjekte edildi. Lesirelin asetatın üst epidural boşluğa uygulandığı A ve B grubunda hayvanların gebelik oranları (sırasıyla % 64, % 45) arasında farklılığın istatistiki açıdan anlamlı olduğu (P<0.05) görüldü. Kas içi uygulama yapılan C ve D grubunda gebelik oranları (sırasıyla % 60, % 52,5) yönüyle arasındaki farkın anlamlı olmadığı (P>0.05) belirlendi. Ayrıca, üst epidural ve kas içi GnRH uygulanan gruplar arasında da istatistiki bir farkın (P>0.05) olmadığı tespit edildi. Sonuç olarak, yapılan çalışmada kendiliğinden östrüse gelen ineklere tohumlama ile birlikte epidural yolla uygulanan GnRH enjeksiyonlarının gebelik oranlarını artırmada faydalı olacağı kanaatine varıldı. 

Keywords

• İnek,Lesirelin asetat,Epidural uygulama,Gebelik oranı

Effect on Pregnancy Rates of Injected Lecirelin Acetate (GnRH analogue) after Insemination in the Cows

Abstract

In the present study the effects of lecirelin acetate injections applied in different ways after artificial insemination on the pregnancy rate of cows were investigated. As a material, 180 cows showing the spontaneous oestrus between 50-120 days after parturation and having the sexual cycle at regular intervals and showing no clinical disorders during the treatment process were used. The cows were randomly divided into 4 groups as A, B, C and D. In the group A (n = 50) 50 µg lecirelin acetate was injected to the sacrococcygeal epidural space of the animals immediately after the artificial insemination . The animals in the group B (n = 40) were injected with 2 ml physiological saline solution by the same route applied to the animals in the group A. The animals in the group C (n = 50) were injected with 50 µg lecirelin acetate intramuscularly immediately after the artificial insemination. The animals in the group D (n = 40) were injected with 2 ml physiological saline solution by the same route applied to the animals in the group C. Statistically significant in difference (P <0.05) were observed between the pregnancy rates of groups A and B (64%) and (45%). It was detected that there was no significant difference (P>0.05) in the pregnancy rates of the groups C and D (60% and 52,5%, respectively). In addition, no significant difference (P>0.05) was observed between the group A (applied epidural GnRH) and C (applied intramuscular GnRH). As a result, it was concluded that either intramuscular or epidural administration of Lecirelin Acetate to cows showing spontaneous oestrus can be used after artificial insemination to increase the pregnancy rates.

Keywords

• Cow,Lecirelin acetate,Epidural treatment,Pregnancy rate

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