Serum Triiodothyronine, Thyroxine, and Thyroid Stimulating Hormone Concentrations of Domestic Female Cats at Different Reproductive Stages

Year 2020, , 200 - 205, 23.12.2020

Ruhi Kabakçı , Taha Burak Elifoglu

https://doi.org/10.31196/huvfd.819930

Abstract

Thyroid hormones have various roles in different physiological systems in the body. Thus, thyroid dysfunction is common in cats, in this study, we aimed to determine the normal values of triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) in the blood of female cats at different phases of the estrous cycle. Queens were divided into three groups as estrous (n=14), diestrus (n=12), and interestrus (n=10) according to findings of vaginal cytology, ovarian inspection, and serum estradiol (E2) and progesterone (P4) concentrations. Blood samples were collected before the ovariohysterectomy, and the obtained sera were analyzed for free T3, free T4, TSH, E2, and P4. The results showed that the highest T3 and T4 concentrations were found in cats at interestrus while the lowest T3 and T4 concentrations were found at diestrus and estrus, respectively. The level of TSH in all cats was below the detection limit of the assay. The mean concentrations of thyroid-related hormones in each group showed non-significant variations (P>0.05). The correlation between ovarian and thyroidal hormones was not statistically significant (P>0.05). In conclusion, it is required to further comprehensive/experimental studies to exhibit the interaction between ovarium and thyroid gland because of its importance.

Keywords

TSH, Feline, Thyroid hormones, Estrous stages, Reproductive cycle

Supporting Institution

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Project Number

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Thanks

We would like to thank Dear Dr. Ufuk Kaya for his valuable contribution to statistical analysis. However, this study did not receive any kind of financial support.

Farklı Üreme Dönemindeki Dişi Kedilerin Serum Triiyodotironin, Tiroksin ve Tiroit Uyarıcı Hormon Konsantrasyonları

Abstract

Tiroit hormonları vücuttaki birçok fizyolojik sistemin gelişim ve fonksiyonlarına dahil olmaktadır. Kedilerde tiroit bozuklukları sık görüldüğünden, bu çalışmada östrus siklusunun farklı evrelerindeki dişi kedilerin kanında bulunan tiriyodotironin (T3), tiroksin (T4) ve tiroit uyarıcı hormonun (TSH) normal değerlerinin belirlemesi amaçlandı. Kediler vajinal sitoloji, ovaryum muayenesi ve serum östrojen (E2) ve progesteron (P4) konsantrasyonlarının bulgularına göre östrus (n=14), diöstrus (n=12) ve interestrus (n=10) olmak üzere üç gruba ayrıldı. Ovariohisterektomiden önce kan örnekleri toplandı ve elde edilen serumlardan E2 ve P4'ün yanı sıra serbest T3, serbest T4 ve TSH analizi yapıldı. Bu çalışmanın sonuçları, en yüksek T3 ve T4 konsantrasyonlarının interöstrusdaki kedilerde olduğunu, en düşük T3 ve T4 konsantrasyonlarının sırasıyla diöstrus ve östrusdaki kedilerde olduğunu gösterdi. Tüm kedilerdeki serum TSH seviyeleri ise test kitinin tespit sınırının altındaydı. Gruplardaki tiroitle ilgili hormonların ortalama konsantrasyonları anlamlı olmayan farklılıklar gösterdi (P> 0,05). Ayrıca ovaryum ve tiroit hormonları arasındaki korelasyon istatistiksel olarak anlamlı bulunmadı (P> 0,05). Sonuç olarak, önemi nedeniyle ovaryum ve tiroit bezi arasındaki etkileşimi ortaya koymak için daha kapsamlı/deneysel çalışmalara ihtiyaç olduğu düşünüldü.

Keywords

TSH, kedi, Tiroit hormonları, Üreme döngüsü, Östrus siklusu

Project Number

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