Fare (Balb/C mice ) ve Sıçan (Wistar Albino Rat)'da Articulatio Genus’un Karşılaştırılmalı Morfolojik İncelenmesi
Abstract
Diz eklemi vücuttaki konumu nedeniyle travmalara açık ve korunmasız bir eklemdir. Bölgenin yapısı, farklı hayvan türlerinde morfolojik ve görüntüleme teknikleri gibi yöntemlerle ortaya konulsada hala konu ile ilgili eksik kısımlar bulunmaktadır. Altışar adet erişkin fare ve sıçanın kullanıldığı bu çalışmada articulatio genus'un karşılaştırmalı morfolojik incelemesinin yapılarak literatür eksiklerinin giderilmesi amaçlandı. Sıçanda insana benzer şekilde trochlea ossis femoris’i yanlardan sınırlayan labium laterale, labium mediale’ye göre daha proksimal’den başlarken farede bu yapılar diğer evcil memelilere benzer olarak aynı mesafeden başlamaktaydı. Meniscus’lerin şekli sıçanda ve farede farklıydı. Sıçanda her iki meniscus’de “C” harfi şeklindeydi. Fakat lateral meniscus insandakinin tersi olarak daha geniş yapıdaydı. Farede lateral meniscus tek parçalı iken medial meniscus iki parçalı melek kanadı görünümündeydi. Her iki türdede meniscus içerisinde kemik dokuya rastlanıldı. Femur’un distal kondüllerinde yer alan fabella’nın sayısı ve şekli sıçanda genel olarak köpeğe benzesede medial fabella’nın yuvarlak olması ve popliteal fabella’nın konumu farklılık oluşturdu. Farede saptanan iki fabella da yaklaşık olarak aynı boyuttaydı ve şekil olarak şapkaya benzemekteydi. Bu çalışma ile elde edilen verilerin literatürüne katkı sağlayacağı düşünüldü.
Ethical Statement
Bu çalışma “Hayvan Deneyleri Etik Kurullarının Çalışma Usul ve Esaslarına Dair Yönetmelik” Madde 8 (k) gereği HADYEK iznine tabi değildir.
Supporting Institution
Bu çalışma için herhangi finansal destek bulunmamaktadır.
References
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- Carballo CB, Hutchinson ID, Album ZM, Mosca MJ, Hall A, Rodeo Jr, S., ... and Rodeo SA, 2018: Biomechanics and microstructural analysis of the mouse knee and ligaments. J Knee Surg, 31(06), 520-527.
- Charles JP, Cappellari O, Spence AJ, Wells DJ, Hutchinson JR, 2016: Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model. J Anat, 229(4), 514-535.
- Dere F, 2012: Anatomi Atlası ve Ders Kitabı. 6. Baskı, Adana: Nobel Tıp Kitapevleri.
- Dursun N, 2008: Veteriner Anatomi I (12. Baskı). Medisan Yayınevi.
- Dyce KM, Sack WO, Wensing CJG, 2010: Textbook of veterinary anatomy. 4th ed. United States, Missouri: Saunders Elsevier.
- Esmer AF, Başarır K, Binnet M, 2011: Diz ekleminin cerrahi anatomisi. TOTBİD Dergisi, 10 (1):38 44.
- Fowlie JG, 2011: Functional anatomy of the equine meniscus: Pathogenesis and pathophysiology of injury to the cranial horn of the medial meniscus. Michigan State University. Large Animal Clinical Sciences.
- Glasson SS, Chambers MG, Van Den Berg WB, Little CB, 2010: The OARSI histopathology initiative- recommendations for histological assessments ofosteoarthritis in the mouse. Osteoarthr Cartil, 18 Suppl 3, S17–S23.
- Hildebrand C, Öqvist G, Brax L, Tuisku F, 1991: Anatomy of the rat knee joint and fibre composition of a major articular nerve. Anat Rec, 229(4), 545-555.
- König HE, Liebich HG, 2020: Veterinry Anatomy of Domestic Animals: Textbook and Colour Atlas, Barnes & Noble. Lin X, Xing L, 2018: Ultrasound as a New Imaging Tool to Assess Pathological Change of Joints in Preclinical Mouse Models of Osteoarthritis. J Orthop Physiother, 1(1), 102.
- Maulet BEB, Mayhew IG, Jones E, Booth TM, 2005: Radiographic anatomy of the soft tissue attachments of the equine stifle. Equine Vet J, 37(6), 530-535.
- Oláh T, Michaelis JC, Cai X, Cucchiarini M, Madry H, 2021: Comparative anatomy and morphology of the knee in translational models for articular cartilage disorders. Part II: Small animals. Ann Anat, 234, 151630.
- Pedersen HE, 1949: The ossicles of the semilulnar cartilages of rodents. Anat Rec, 105 (1), 1-9.
- Takahashi I, Matsuzaki T, Kuroki H, Hoso M, 2019: Disuse histological changes of an unloading environment on joint components in rat knee joints. Osteoarthr Cartil, 1(1-2), 100008.
- Üstüner Y, 2006: Total Diz Artroplastisi Erken Dönem Sonuçları (uzmanlık tezi). Đstanbul: TC Sağlık Bakanlığı Haseki Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği.
- Wendling O, Hentsch D, Jacobs H, Lemercier N, Taubert S, Pertuy F., ... and Herault, Y, 2021: High resolution episcopic microscopy for qualitative and quantitative data in phenotyping altered embryos and adult mice using the new “Histo3d” system. Biomedicines, 9(7), 767.
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Abstract
The knee joint is vulnerable to trauma and unprotected due to its location in the body. Although the structure of the region has been revealed by methods such as morphological and imaging techniques in different animal species, there still needs to be parts on the subject. This study, aimed to fill the literature gaps by performing a comparative morphological examination of the articulatio genus in which six adult mice and six rats were used. In the rat, similar to humans, the labium laterale, which limits the trochlea ossis femoris from the sides, started more proximal than the labium mediale, whereas in the mouse, these structures started from the same distance, similar to other domestic mammals. Both menisci were shaped like the letter "C" in the rat. However, the lateral meniscus was more comprehensive than in humans. While the lateral meniscus was in one piece, the medial meniscus looked like a two-piece angel wing in the mouse. Bone tissue was found within the meniscus in both species. Although the number and shape of the fabella located in the distal condyles of the femur were generally similar to the dog in the rat, the roundness of the medial fabella and the location of the popliteal fabella made a difference. The two fabellas detected in the mouse were approximately the same size and resembled a hat in shape. It is thought that the data obtained from this study will contribute to the literature.
References
- Akkoyun Sert Ö, Eken E, 2024; Yeni Zelanda Tavşanlarında Diz Ekleminin Bilgisayarlı Tomografi ve Manyetik Rezonans Görüntülerinden Üç Boyutlu Verilerinin Değerlendirilmesi. Selçuk Sağlık Dergisi, 5(1), 70 – 78.
- Carballo CB, Hutchinson ID, Album ZM, Mosca MJ, Hall A, Rodeo Jr, S., ... and Rodeo SA, 2018: Biomechanics and microstructural analysis of the mouse knee and ligaments. J Knee Surg, 31(06), 520-527.
- Charles JP, Cappellari O, Spence AJ, Wells DJ, Hutchinson JR, 2016: Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model. J Anat, 229(4), 514-535.
- Dere F, 2012: Anatomi Atlası ve Ders Kitabı. 6. Baskı, Adana: Nobel Tıp Kitapevleri.
- Dursun N, 2008: Veteriner Anatomi I (12. Baskı). Medisan Yayınevi.
- Dyce KM, Sack WO, Wensing CJG, 2010: Textbook of veterinary anatomy. 4th ed. United States, Missouri: Saunders Elsevier.
- Esmer AF, Başarır K, Binnet M, 2011: Diz ekleminin cerrahi anatomisi. TOTBİD Dergisi, 10 (1):38 44.
- Fowlie JG, 2011: Functional anatomy of the equine meniscus: Pathogenesis and pathophysiology of injury to the cranial horn of the medial meniscus. Michigan State University. Large Animal Clinical Sciences.
- Glasson SS, Chambers MG, Van Den Berg WB, Little CB, 2010: The OARSI histopathology initiative- recommendations for histological assessments ofosteoarthritis in the mouse. Osteoarthr Cartil, 18 Suppl 3, S17–S23.
- Hildebrand C, Öqvist G, Brax L, Tuisku F, 1991: Anatomy of the rat knee joint and fibre composition of a major articular nerve. Anat Rec, 229(4), 545-555.
- König HE, Liebich HG, 2020: Veterinry Anatomy of Domestic Animals: Textbook and Colour Atlas, Barnes & Noble. Lin X, Xing L, 2018: Ultrasound as a New Imaging Tool to Assess Pathological Change of Joints in Preclinical Mouse Models of Osteoarthritis. J Orthop Physiother, 1(1), 102.
- Maulet BEB, Mayhew IG, Jones E, Booth TM, 2005: Radiographic anatomy of the soft tissue attachments of the equine stifle. Equine Vet J, 37(6), 530-535.
- Oláh T, Michaelis JC, Cai X, Cucchiarini M, Madry H, 2021: Comparative anatomy and morphology of the knee in translational models for articular cartilage disorders. Part II: Small animals. Ann Anat, 234, 151630.
- Pedersen HE, 1949: The ossicles of the semilulnar cartilages of rodents. Anat Rec, 105 (1), 1-9.
- Takahashi I, Matsuzaki T, Kuroki H, Hoso M, 2019: Disuse histological changes of an unloading environment on joint components in rat knee joints. Osteoarthr Cartil, 1(1-2), 100008.
- Üstüner Y, 2006: Total Diz Artroplastisi Erken Dönem Sonuçları (uzmanlık tezi). Đstanbul: TC Sağlık Bakanlığı Haseki Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği.
- Wendling O, Hentsch D, Jacobs H, Lemercier N, Taubert S, Pertuy F., ... and Herault, Y, 2021: High resolution episcopic microscopy for qualitative and quantitative data in phenotyping altered embryos and adult mice using the new “Histo3d” system. Biomedicines, 9(7), 767.
- Xu H, Bouta EM, Wood RW, Schwarz EM, Wang Y, Xing L, 2017: Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis. Bone Res, 5(1), 1-7.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Anatomy and Physiology |
| Journal Section | Research |
| Authors | |
| Publication Date | June 25, 2024 |
| Submission Date | March 18, 2024 |
| Acceptance Date | May 23, 2024 |
| Published in Issue | Year 2024 Volume: 13 Issue: 1 |
