İyon kanalları ve kanser

Mümin Alper Erdoğan; Oytun Erbaş

TR

İyon kanalları ve kanser

Abstract

İyon kanalları yaşayan hücrelerin temel yapısal elemanları içindedir. Son yıllarda iyon kanallarının tümör gelişiminde ve kanserin ilerleyişinde hayati öneme sahip olduğu ortaya çıkmıştır. Normal bir hücrenin kansere dönüşümü sırasında iyon kanallarının ekspresyonunu etkileyebilen veya iyon kanal aktivitesinde bir değişime neden olabilen bir seri genetik değişim meydana gelmektedir. İyon kanalları kanser hücresinde proliferasyon, apoptoz, migrasyon, anjiyogenez ve metastaz ile ilişkilidir. İyon kanalları halen onkolojide yeni bir araştırma alanını oluşturmaktadır. Sonuçta iyon kanallarının kanserle ilgili anahtar süreçlerdeki rollerinin ayrıntılı bir şekilde anlaşılması, tanı ve tedavi için moleküler-hedefli araçların geliştirilmesini kolaylaştıracaktır.

Keywords

Kanser,iyon kanalları,metastaz,yeni hedefler,proliferasyon

References

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Mümin Alper Erdoğan ^*

Oytun Erbaş This is me

Publication Date

April 18, 2018

Submission Date

February 5, 2018

Acceptance Date

-

Published in Issue

Year 2018 Volume: 4 Number: 1

IZ

https://izlik.org/JA24SC42RX

Cite

RIS / Bibtex

APA

Erdoğan, M. A., & Erbaş, O. (2018). İyon kanalları ve kanser. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, 4(1), 49-62. https://izlik.org/JA24SC42RX

AMA

1.Erdoğan MA, Erbaş O. İyon kanalları ve kanser. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi. 2018;4(1):49-62. https://izlik.org/JA24SC42RX

Chicago

Erdoğan, Mümin Alper, and Oytun Erbaş. 2018. “İyon Kanalları Ve Kanser”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 4 (1): 49-62. https://izlik.org/JA24SC42RX.

EndNote

Erdoğan MA, Erbaş O (April 1, 2018) İyon kanalları ve kanser. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 4 1 49–62.

IEEE

[1]M. A. Erdoğan and O. Erbaş, “İyon kanalları ve kanser”, İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, vol. 4, no. 1, pp. 49–62, Apr. 2018, [Online]. Available: https://izlik.org/JA24SC42RX

ISNAD

Erdoğan, Mümin Alper - Erbaş, Oytun. “İyon Kanalları Ve Kanser”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi 4/1 (April 1, 2018): 49-62. https://izlik.org/JA24SC42RX.

JAMA

1.Erdoğan MA, Erbaş O. İyon kanalları ve kanser. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi. 2018;4:49–62.

MLA

Erdoğan, Mümin Alper, and Oytun Erbaş. “İyon Kanalları Ve Kanser”. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi, vol. 4, no. 1, Apr. 2018, pp. 49-62, https://izlik.org/JA24SC42RX.

Vancouver

1.Mümin Alper Erdoğan, Oytun Erbaş. İyon kanalları ve kanser. İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi [Internet]. 2018 Apr. 1;4(1):49-62. Available from: https://izlik.org/JA24SC42RX