Determination of vitamin B12, folate, and ferritin levels of inpatients in a psychiatry clinic: A one-year retrospective study

Abstract

Objectives: This study aims to compare the vitamin B12, folate, and ferritin levels of inpatients in a psychiatry clinic.
Materials and methods: The study included 286 inpatients (178 males, 108 females; mean age 35.4±12.9 years; range, 15 to 76 years) treated in
Adiyaman University Training and Research Hospital psychiatry clinic between 01 January 2017 and 31 December 2017. Patients’ diagnoses and vitamin
B12, folate, and ferritin levels were examined retrospectively.
Results: The most common diagnoses were schizophrenia (23.4%), bipolar affective disorder (23.1%), and major depressive disorder (11.5%). While
there was no significant difference in vitamin B12 levels according to sex (p=0.850), folate level was significantly lower in males (p=0.001) and ferritin
level was significantly lower in females (p=0.001). No difference was detected in the levels of vitamin B12, folate and ferritin in the comparison between
diagnoses.
Conclusion: Deficiency in vitamin B12, folate, and ferritin levels may cause psychiatric symptoms. Due to the high number of patients with low vitamin
B12 levels in our study, more attention may be paid to vitamin B12 replacement. Ferritin deficiency in females and folate deficiency in males are
noteworthy. Further research are needed to identify more specific and detailed algorithms related to vitamin B12, folate, and ferritin to support the
findings of this study and optimize the care given to patients suffering from psychiatric syndromes.

Keywords

• Ferritin
• folic acid
• inpatients
• psychiatry
• retrospective study
• vitamin B12

Bir psikiyatri kliniğinde yatan hastalarda B12 vitamini, folat ve ferritin düzeylerinin belirlenmesi: Bir yıllık retrospektif bir çalışma

Abstract

Amaç: Bu çalışmada bir psikiyatri kliniğinde yatan hastaların B12 vitamini, folat ve ferritin düzeyleri karşılaştırıldı.

Gereç ve yöntemler: Çalışmaya 01 Ocak 2017 ve 31 Aralık 2017 tarihleri arasında Adıyaman Üniversitesi Eğitim ve Araştırma Hastanesi psikiyatri servisinde yatarak tedavi gören 286 hasta (178 erkek, 108 kadın; ort. yaş 35.4±12.9 yıl; dağılım, 15-76 yıl) dahil edildi. Hastaların tanıları ve B12 vitamini, folat ve ferritin düzeyleri retrospektif olarak incelendi.

Bulgular: En sık görülen tanılar şizofreni (%23.4), bipolar affektif bozukluk (%23.1) ve majör depresif bozukluk (%11.5) idi. Cinsiyete göre B12 vitamini düzeylerinde anlamlı farklılık yokken (p=0.850) erkeklerde folat düzeyi (p=0.001) ve kadınlarda ferritin düzeyi (p=0.001) anlamlı olarak düşük idi. Tanılar arasındaki karşılaştırmada; B12 vitamini, folat ve ferritin düzeyleri arasında farklılık tespit edilmedi.

Sonuç: B12 vitamini, folat ve ferritin düzeylerinde eksiklik psikiyatrik semptomlara neden olabilir. Çalışmamızda B12 vitamini düzeyi düşük olan hasta sayısının fazla olmasına bağlı olarak B12 vitamini replasmanında daha dikkatli olunabilir. Kadınlardaki ferritin eksikliği ve erkeklerdeki folat eksikliği dikkat çekicidir. Bu çalışmanın bulgularını desteklemek ve psikiyatrik sendromu olan hastalara verilen bakımın optimize edilmesi için B12 vitamini, folat ve ferritine ilişkin daha spesifik ve ayrıntılı algoritmaları belirlemek amacıyla ileri araştırmalar gerekmektedir.

Keywords

• Ferritin
• folik asit
• yatan hastalar
• psikiyatri
• retrospektif çalışma
• B12 vitamini

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