İnatçı hipoglisemi lenfoma relapsının bir habercisi olabilir mi?
Year 2018,
Volume: 4 Issue: 4, 200 - 202, 03.01.2019
Damla Çağla Patır
,
Ahmet Peker
Harun Akar
Abstract
Hodgkin lenfoma bir lenfoproliferatif malignite olup genellikle soliter ya da generalize lenfadenomegali ile karakterizedir. Hipoglisemi, solid organ tümörlerine bağlı görülebilen paraneoplastik bir sendrom olarak prezente olabilmektedir. Literatürde Hodgkin lenfomaya bağlı gelişen hipoglisemiye dair sınırlı sayıda olgu bulunmaktadır. Bu yazıda kür Hodgkin lenfoma öz geçmişi olan tekrarlayan hipoglisemiler nedeni ile tarafımızca tetkik edilirken Hodgkin lenfoma nüksü saptanan bir paraneoplastik hipoglisemi olgusu sunuldu.
References
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Year 2018,
Volume: 4 Issue: 4, 200 - 202, 03.01.2019
Damla Çağla Patır
,
Ahmet Peker
Harun Akar
References
- 1. Villani F., Viola G., Vismara C., Lung function and serum concentrations of different cytokines in patients submitted to radiotherapy and intermediate/high dose chemotherapy for hodgkin’s disease. Anticancer Research 2002;22:2403-8.
- 2. Greer JP, Foerster J, Rodgers GM, Paraskevas F, Glader B, Arber DA, Means RT Jr, editors. Wintrobe’s Clinical Haematology, 12th ed. Philadelphia: Lippincot Williams and Wilkins; 2009.
- 3. Scott K. Non-islet cell tumor hypoglycemia. J Pain Symptom Manage 2009;37:1-3.
- 4. Bodnar TW, Acevedo MJ, Pietropaolo M. Management of non-islet-cell tumor hypoglycemia: a clinical review. J Clin Endocrinol Metab 2014;99:713-22.
- 5. Pink D, Schoeler D, Lindner T, Thuss-Patience PC, Kretzschmar A, Knipp H, et al. Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report of two cases. J Clin Oncol 2005;23:6809-11.
- 6. Lim HC, Munshi LB, Sharon D. Persistent Hypoglycemia in Patient with Hodgkin's Disease. Case Rep Oncol Med 2015;2015:820286.
- 7. Pavelic K, Odavic M, Pekic B, Hrsak I, Vuk-Pavlovic S. Correlation of substance(s) immunologically cross-reactive with insulin, glucose and growth hormone in Hodgkin lymphoma patients. Cancer Lett 1982;17:81-6.
- 8. Kulkarni A, Zlabek J, Farnen J, Capla R. Recurrent hypoglycemia and hypothermia in a patient with Hodgkin's disease. Haematologica 2006;91:CR50.
- 9. Braund WJ, Naylor BA, Williamson DH, Buley ID, Clark A, Chapel HM, et al. Autoimmunity to insulin receptor and hypoglycaemia in patient with Hodgkin's disease. Lancet 1987;1:237-40.
- 10. Abbasi A, Power L. Insulin and insulinlike activity in extracts of tumors associated with hypoglycemia. Diabetes 1973;22:762-7.