Abstract
Objectives: Our aim was to answer the question of Is there a statistically significant relationship between plasma ischemia modified albumin (IMA) levels of acute kidney failure (AKF) patients before the hospital admission and their clinical healing progress.Patients and methods: Between August 2014 and October 2014, we included 18 patients (9 males, 9 females) who were diagnosed with AKF and investigated the relationship between patients’ blood levels of IMA before admission to the hospital and clinical progress.Results: Plasma IMA average of 18 patients before treatment was 628. After treatment plasma IMA average was 428. A statistically reasonable relationship was detected.Conclusion: Our study suggest that hospital stay of patients who had higher plasma levels of IMA was remarkably longer than who had lower plasma levels of IMA. Also we detected that the more plasma levels of IMA increased, the need of patients’ for hemodialysis increased
References
- Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005;16:3365-70.
- Xue JL, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, et al. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol 2006;17:1135-42.
- Kellum JA, Angus DC. Patients are dying of acute renal failure. Crit Care Med 2002;30:2156-7.
- Goldman L, Ausiello D. Cecil Medicine. Çeviri editörü: Ünal S. Elsevier Türkçe 2011. s. 238.
- Piwowar A, Knapik-Kordecka M, Warwas M. Comparison of the usefulness of plasma levels of oxidatively modified forms of albumin in estimating kidney dysfunction in diabetic patients. Clin Invest Med 2010;33:E109.
- Dahiya K, Kumawat M, Kaur R, Yadav S, Singh J, Ghalaut VS, et al. Ischemia modified albumin and nitric oxide in diabetic nephropathy. Journal of Diabetology, February 2013;1:1-5.
Akut böbrek yetmezliği tanılı hastalarda tedavi öncesi ve sonrası iskemik modifiye albümin düzeylerinin incelenmesi
Abstract
Amaç: Bu çalışmadaki amacımız akut böbrek yetmezliği (ABY) olan hastalarda iskemi modifiye albümin (İMA) düzeyleri ile klinik iyileşme arasında istatistiksel olarak anlamlı bir fark var mıdır? sorusuna cevap bulabilmektir.
Hastalar ve yöntemler: Ağustos 2014 - Ekim 2014 tarihleri arasında kliniğimizde ABY tanısı konulan, çalışma kriterlerini karşılayan 18 hasta (9 erkek, 9 kadın) çalışmaya dahil edildi. Bu çalışmayla hastaneye yatmadan önceki İMA düzeyleri ile klinik iyileşme sonrası İMA düzeyleri arasındaki ilişki incelendi.
Bulgular: Hastaların tedavi öncesi İMA düzeyi ortalaması 628, tedavi sonrası İMA düzey ortalaması ise 428 olarak tespit edildi. İstatistiksel olarak her iki durum arasında anlamlı fark saptandı.
Sonuç: Çalışma sonucunda dikkat çekici olarak İMA değeri yüksek olan hastaların hastanede yatış süresinin uzun olduğu g.rüldü. Ayrıca İMA düzeyi ile diyaliz ihtiyacı arasında anlamlı ilişki saptandı.
Anahtar sözcükler: Diyaliz; iskemik modifiye albümin; böbrek yetmezliği.
References
- Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 2005;16:3365-70.
- Xue JL, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, et al. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol 2006;17:1135-42.
- Kellum JA, Angus DC. Patients are dying of acute renal failure. Crit Care Med 2002;30:2156-7.
- Goldman L, Ausiello D. Cecil Medicine. Çeviri editörü: Ünal S. Elsevier Türkçe 2011. s. 238.
- Piwowar A, Knapik-Kordecka M, Warwas M. Comparison of the usefulness of plasma levels of oxidatively modified forms of albumin in estimating kidney dysfunction in diabetic patients. Clin Invest Med 2010;33:E109.
- Dahiya K, Kumawat M, Kaur R, Yadav S, Singh J, Ghalaut VS, et al. Ischemia modified albumin and nitric oxide in diabetic nephropathy. Journal of Diabetology, February 2013;1:1-5.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | September 17, 2015 |
| Published in Issue | Year 2015 Volume: 1 Issue: 2 |
