Abstract
3,4-methylenedioxymethamphetamine (MDMA, ecstasy), which is a kind of synthetic amphetamine, is widely used in last years among young population. It is abused because of addiction and appliance to emergency service becaouse of that drug atrracts more and more attention. Twenty five year-old male patient without any other comorbidities, applied to the emergency room with chest pain and blurred vision. His chest pain was intermittent, did not spread to any aother location, and each time lastes 1-2 minutes. His physical examination was completely normal but his ecg revealed ST elevation in derivations of D1-aVL. When he was deeply questioned, he told that he had taken several pills of ectasy two hours before the admissin to the hospital. After that, cardiologists thought ecg changes might be due to vasospastic changes. That’s why they started to treat patient with nitrates. After appliance of nitrate his ECG became completely normal. We wanted to emphasize with our case report that whenever a young person with chest pain and without any comorbidities applies to emergency room, we should pay attention to probability of drug abuse and question them deeply. Drug abuse can lead mortal cardiac side effects
References
- Fathelrahman AI, Ab Rahman AF, Mohd Zain Z. MS 04-044: demographic features of drug and chemical poisoning in northern Malaysia. Clin Toxicol (Phila) 2005;43:89-94.
- Akkose S, Bulut M, Armagan E, Cebicci H, Fedakar R. Acute poisoning in adults in the years 1996-2001 treated in the Uludag University Hospital, Marmara Region, Turkey. Clin Toxicol (Phila) 2005;43:105-9.
- Hatzitolios AI, Sion ML, Eleftheriadis NP, Toulis E, Efstratiadis G, Vartzopoulos D, et al. Parasuicidal poisoning treated in a Greek medical ward: epidemiology and clinical experience. Hum Exp Toxicol 2001;20:611-7.
- Dorado Pombo S, Martín Fernández J, Sabugal Rodelgo G, Caballero Vallés PJ. Epidemiology of acute poisoning: study of 613 cases in the Community of Madrid in 1994. Rev Clin Esp 1996;196:150-6. [Abstract]
- Mauri MC, Cerveri G, Volonteri LS, Fiorentini A, Colasanti A, Manfré S, et al. Parasuicide and drug self- poisoning: analysis of the epidemiological and clinical variables of the patients admitted to the Poisoning Treatment Centre (CAV), Niguarda General Hospital, Milan. Clin Pract Epidemiol Ment Health 2005;1:5.
- Owens D, Wood C, Greenwood DC, Hughes T, Dennis M. Mortality and suicide after non-fatal self- poisoning: 16-year outcome study. Br J Psychiatry 2005;187:470-5.
- Available from: http://tr.wikipedia.org/wiki/Ekstazi [Eriim tarihi: 02.06.2008]
- Gahlinger PM. Club drugs: MDMA, gamma- hydroxybutyrate (GHB), Rohypnol, and ketamine. Am Fam Physician 2004;69:2619-26.
- Hollander JE. The management of cocaine- associated myocardial ischemia. N Engl J Med 1995;333:1267-72.
- Hoffman RJ. MDMA (ecstasy) intoxication. Available from: http://www.uptodate.com [Eriim tarihi: 06.06.2008]
- Kalant H. The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs. CMAJ 2001;165:917-28.
- http://www.drugfreeamerica.org Eriflim tarihi 06.06.2008.
- Burillo-Putze G, García BC, González AM. New cannabinoids use (Spice) and their detection in emergency departments. An Pediatr (Barc) 2010;73:287-8. [Abstract]
- Müller H, Huttner HB, Köhrmann M, Wielopolski JE, Kornhuber J, Sperling W. Panic attack after spice abuse in a patient with ADHD. Pharmacopsychiatry 2010;43:152-3.
- Ayhan H, Aslan AN, Süygün H, Durmaz T. Bonsai induced acute myocardial infarction. [Article in Turkish] Turk Kardiyol Dern Ars 2014;42:560-3.
Abstract
3,4-metilenedioksimetamfetamin (MDMA, ekstasi), amfetamin türevi bir maddedir ve son yıllarda genç/genç-erişkin popülasyonda oldukça yaygın olarak kullanılmaktadır. Maddenin bağımlılık yapıcı etkisinin yanı sıra yaygın k.tüye kullanımı, tüm dünyada acil servislere çok çeşitli nedenlerle başvuruları arttırması nedeniyle ilgi odağıdır. Yirmi beş yaşında bilinen kronik hastalık .yküsü olmayan erkek hasta acil servise çarpıntı, bulanık görme, gelip geçici ve yayılımı olmayan 1-2 dakika kadar süren g.ğüs ağrısı yakınması ile başvurdu. Çekilen EKG'lerinde D1-AVL derivasyonlarında ST segment elevasyonu saptandı. Hastanın anamnezi derinleştirildiğinde yaklaşık iki saat önce keyif verici amaçlı, sayısı net olmayan ekstazi hapı kullandığı öğrenildi. Tipik g.ğüs ağrısının olmaması, eleve olan segmentlerin dışında resiprokal değişikliklerin izlenmemesi nedeniyle öncelikle ekstazi alımına bağlı vazospastik değişiklik düşünüldü. Verilen nitrat sonrası EKG bulgusu düzeldi. Biz bu olgu ile bu tür uyuşturucu madde kullanımı sonrasında da ciddi kardiyak yan etkiler gelişebileceğini ve herhangi bir kardiyovasküler risk fakt.rü olmayan, akut g.ğüs ağrılı genç hastalarda bunun mutlaka sorgulanıp akılda tutulması gerektiğini vurgulamak istedik.
Anahtar sözcükler: Amfetamin; ekstazi; ST elevasyonlu miyokard enfarktüsü.
References
- Fathelrahman AI, Ab Rahman AF, Mohd Zain Z. MS 04-044: demographic features of drug and chemical poisoning in northern Malaysia. Clin Toxicol (Phila) 2005;43:89-94.
- Akkose S, Bulut M, Armagan E, Cebicci H, Fedakar R. Acute poisoning in adults in the years 1996-2001 treated in the Uludag University Hospital, Marmara Region, Turkey. Clin Toxicol (Phila) 2005;43:105-9.
- Hatzitolios AI, Sion ML, Eleftheriadis NP, Toulis E, Efstratiadis G, Vartzopoulos D, et al. Parasuicidal poisoning treated in a Greek medical ward: epidemiology and clinical experience. Hum Exp Toxicol 2001;20:611-7.
- Dorado Pombo S, Martín Fernández J, Sabugal Rodelgo G, Caballero Vallés PJ. Epidemiology of acute poisoning: study of 613 cases in the Community of Madrid in 1994. Rev Clin Esp 1996;196:150-6. [Abstract]
- Mauri MC, Cerveri G, Volonteri LS, Fiorentini A, Colasanti A, Manfré S, et al. Parasuicide and drug self- poisoning: analysis of the epidemiological and clinical variables of the patients admitted to the Poisoning Treatment Centre (CAV), Niguarda General Hospital, Milan. Clin Pract Epidemiol Ment Health 2005;1:5.
- Owens D, Wood C, Greenwood DC, Hughes T, Dennis M. Mortality and suicide after non-fatal self- poisoning: 16-year outcome study. Br J Psychiatry 2005;187:470-5.
- Available from: http://tr.wikipedia.org/wiki/Ekstazi [Eriim tarihi: 02.06.2008]
- Gahlinger PM. Club drugs: MDMA, gamma- hydroxybutyrate (GHB), Rohypnol, and ketamine. Am Fam Physician 2004;69:2619-26.
- Hollander JE. The management of cocaine- associated myocardial ischemia. N Engl J Med 1995;333:1267-72.
- Hoffman RJ. MDMA (ecstasy) intoxication. Available from: http://www.uptodate.com [Eriim tarihi: 06.06.2008]
- Kalant H. The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs. CMAJ 2001;165:917-28.
- http://www.drugfreeamerica.org Eriflim tarihi 06.06.2008.
- Burillo-Putze G, García BC, González AM. New cannabinoids use (Spice) and their detection in emergency departments. An Pediatr (Barc) 2010;73:287-8. [Abstract]
- Müller H, Huttner HB, Köhrmann M, Wielopolski JE, Kornhuber J, Sperling W. Panic attack after spice abuse in a patient with ADHD. Pharmacopsychiatry 2010;43:152-3.
- Ayhan H, Aslan AN, Süygün H, Durmaz T. Bonsai induced acute myocardial infarction. [Article in Turkish] Turk Kardiyol Dern Ars 2014;42:560-3.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | September 17, 2015 |
| Published in Issue | Year 2015 Volume: 1 Issue: 2 |
