COVİD-19 VACCİNATİON RATES IN PATİENTS WİTH SEVERE MENTAL

Year 2023, Volume: 6 Issue: 3, 435 - 444, 27.12.2023

Osman Hasan Tahsin Kılıç , Gülsüm Akdeniz , Merziye Gökçe Göksu , Burcu Gülün Manoğlu

https://doi.org/10.52538/iduhes.1334814

Abstract

The pandemic is thought to affect patients with severe mental illness (SMI). There are no data on COVID-19 vaccination in patients with SMI in Turkey. The aim of our study is to determine the vaccination rates and demographic and clinical characteristics that may be associated with vaccination in SMI patients followed in a community mental health center (TRSM). Data including demographic and clinical characteristics of 307 patients followed in TRSM were obtained. The mean age of the patients was 44.17±11.23. There were 199 (64.8%) men, 205 (66.8%) single, 247 (80.5%) unemployed, 288 (95%) living with their families. 242 (78.8%) were diagnosed with schizophrenia spectrum disorder and 65 (21.2%) were diagnosed with bipolar disorder. 78 (28.9%) of them had a suicide attempt in the past. 118 (38.4%) had chronic co-morbidities. Fifty (16.3%) of the patients had past Covid-19 infection. 257 (83.7%) 1 dose, 246 (80.1%) 2 doses, 173 (56.4%) 3 doses, 61 (19.9%) 4 doses and 9 (2.9%) 5 doses 150 (48.9%) patients were vaccinated. fully vaccinated, 50 (16.3%) unvaccinated and 107 (34.9%) partially vaccinated. In the current study, vaccination rates against covid 19 were lower in SMI patients than in the general population. There was no difference between full or partial/unvaccinated groups in terms of demographic or clinical characteristics except marital status in SMI patients. Organizational changes are needed to increase vaccination rates in SMI patients.

Keywords

Bipolar Disorder, COVID-19, Schizophrenia, Vaccination

Supporting Institution

TÜBİTAK 2209-A

Project Number

1919B012101952

AĞIR RUH HASTALIĞI OLAN HASTALARDA COVİD-19 AŞILAMA ORANLARI

Abstract

Özet
Pandeminin ciddi akıl hastalığı (SMI) olan hastaları etkilediği düşünülüyor. Türkiye'de SMI hastalarında COVID-19 aşısı ile ilgili veri bulunmamaktadır. Çalışmamızın amacı, bir toplum ruh sağlığı merkezinde (TRSM) takip edilen SMI hastalarında aşılama oranları ile aşılama ile ilişkili olabilecek demografik ve klinik özellikleri belirlemektir. TRSM'de izlenen 307 hastanın demografik ve klinik özelliklerini içeren veriler elde edildi. Hastaların yaş ortalaması 44,17±11,23 idi. 199 (%64,8) erkek, 205 (%66,8) bekar, 247 (%80,5) işsiz, 288 (%95) ailesiyle birlikte yaşıyordu. 242 (%78,8) kişiye şizofreni spektrum bozukluğu, 65 (%21,2) kişiye bipolar bozukluk tanısı kondu. 78'i (%28,9) geçmişte intihar girişiminde bulunmuştur. 118'inin (%38,4) kronik yandaş hastalığı vardı. Hastaların 50'sinde (%16,3) daha önce Covid-19 enfeksiyonu geçirilmişti. 257 (%83,7) 1 doz, 246 (%80,1) 2 doz, 173 (%56,4) 3 doz, 61 (%19,9) 4 doz ve 9 (%2,9) 5 doz 150 (%48,9) hasta aşılandı. tam aşılı, 50 (%16,3) aşısız ve 107 (%34,9) kısmen aşılı. Mevcut çalışmada, SMI hastalarında covid 19'a karşı aşılama oranları genel popülasyona göre daha düşüktü. SMI hastalarında medeni durum dışında demografik veya klinik özellikler açısından tam veya kısmi/aşılanmamış gruplar arasında fark yoktu. SMI hastalarında aşılama oranlarını artırmak için organizasyonel değişikliklere ihtiyaç vardır.

Keywords

Bipolar Bozukluk, COVİD-19, Şizofreni, Aşı

Project Number

1919B012101952

References

• Bai, W., Cai, H., Jin, Y., Zhang, Q., Cheung, T., Su, Z., Tang, Y.L., , Ng, C. H.,Xiang, Y.T. (2023). COVID-19 vaccine hesitancy in community-dwelling and hospitalized patients with severe mental illness. Psychological Medicine, 53(9), 4288–4290.
• Current Immunication Recommendations Against Covid-19. https://www.klimik.org.tr/2022/07/11/119309/ Accessed June 12, 2023.
• De Hert, M., Mazereel, V., Detraux, J.,Van Assche, K. (2021). Prioritizing COVID-19 vaccination for people with severe mental illness. World Psychiatry, 20, 54–55.
• De Picker, L. J., Dias, M. C., Benros, M. E., Vai, B., Branchi, I., Benedetti, F., Borsini, A., Leza, J. C., Kärkkäinen, H., Männikkö, M., Pariante, C. M., Güngör, E. S., Szczegielniak, A., Tamouza, R., van der Markt, A., Fusar-Poli, P., Beezhold, J.,Leboyer, M. (2021). Severe mental illness and European COVID-19 vaccination strategies. The lancet. Psychiatry, 8(5), 356–359.
• Hamada, K.,Fan, X. (2020). The impact of COVID-19 on individuals living with serious mental illness. Schizophrenia Research, 222, 3–5.
• Huang, H., Zhu, X. M., Liang, P. W., Fang, Z. M., Luo, W., Ma, Y. M., Zhong, B. L.,Chiu, H.F. (2021). COVID-19 Vaccine Uptake, Acceptance, and Hesitancy Among Persons With Mental Disorders During the Second Stage of China's Nationwide Vaccine Rollout. Frontiers in medicine, 8, 761601.
• Kozloff, N., Mulsant, B. H., Stergiopoulos, V.,Voineskos, A. N. (2020). The COVID-19 global pandemic: Implications for people with schizophrenia and related disorders. Schizophrenia Bulletin, 46, 752–757.
• Mazereel, V., Van Assche, K., Detraux, J.,De Hert, M. (2021). COVID-19 vaccination for people with severe mental illness: why, what, and how?. The lancet. Psychiatry, 8(5), 444– 450.
• Mazereel, V., Vanbrabant, T., Desplenter, F., Detraux, J., De Picker, L., Thys, E., Popelier, K.,De Hert, M. (2021). COVID-19 Vaccination Rates in a Cohort Study of Patients With Mental Illness in Residential and Community Care. Frontiers in psychiatry, 12, 1-13, 805528.
• Miles, L. W., Williams, N., Luthy, K. E., Eden, L. (2019). Adult Vaccination Rates in the Mentally Ill Population: An Outpatient Improvement Project. Journal of the American Psychiatric Nurses Association, 26, 172-180.
• Moreno, C., Wykes, T., Galderisi, S., Nordentoft, M., Crossley, N., Jones, N., Cannon, M., Correll, C. U., Byrne, L., Carr, S., Chen, E. Y. H., Gorwood, P., Johnson, S., Kärkkäinen, H., Krystal, J. H., Lee, J., Lieberman, J., López-Jaramillo, C., Männikkö, M., Phillips, M. R.,Uchida, H., Vieta, E., Vita, A., Arango, C. (2020). How mental health care should change as a consequence of the COVID-19 pandemic. The lancet. Psychiatry, 7(9), 813–824.
• Peritogiannis, V., Drakatos, I., Gioti, P.,Garbi, A. (2023). Vaccination rates against COVID-19 in patients with severe mental illness attending community mental health services in rural Greece. The International journal of social psychiatry, 69(1), 208–215.
• Raffard, S., Bayard, S., Eisenblaetter, M., Attal, J., Andrieu, C., Chereau, I., Fond, G., Leignier, S., Mallet, J., Tattard, P., Urbach, M., Misdrahi, D., Laraki, Y.,Capdevielle, D. (2022). Attitudes towards Vaccines, Intent to Vaccinate and the Relationship with COVID-19 Vaccination Rates in Individuals with Schizophrenia. Vaccines, 10(8), 1228.
• Republic Of Türkiye Ministry Of Health Covid-19 Vaccine Information Platform. https://covid19asi.saglik.gov.tr/ Accessed June 12, 2023.
• Stip, E., Javaid, S.,Amiri, L. (2021). People with mental illness should be included in COVID-19 vaccination. The lancet. Psychiatry, 8(4), 275–276.
• Toubasi, A. A., AbuAnzeh, R. B., Tawileh, H. B. A., Aldebei, R. H.,Alryalat, S. A. S. (2021). A meta-analysis: The mortality and severity of COVID-19 among patients with mental disorders. Psychiatry Research, 299, 1-14, 113856.
• Tzur Bitan, D., Kridin, K., Cohen, A. D., Weinstein, O. (2021). COVID-19 hospitalisation, mortality, vaccination, and postvaccination trends among people with schizophrenia in Israel: a longitudinal cohort study. The lancet. Psychiatry, 8(10), 901–908
• Vai, B., Mazza, M. G., Delli Colli, C., Foiselle, M., Allen, B., Benedetti, F., Borsini, A., Casanova Dias, M., Tamouza, R., Leboyer, M., Benros, M. E., Branchi, I., Fusar-Poli, P.,De Picker, L. J. (2021). Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis. The lancet. Psychiatry, 8(9), 797–812.
• Wiegand, H. F., Maicher, B., Rueb, M., Wessels, P., Besteher, B., Hellwig, S., Pfennig, A., Rohner, H., Unterecker, S., Hölzel, L. P., Philipsen, A., Domschke, K., Falkai, P., Lieb, K.,Adorjan, K. (2022). COVID-19 vaccination rates in hospitalized mentally ill patients compared to the general population in Germany: Results from the COVID Ψ Vac study. European psychiatry : the journal of the Association of European Psychiatrists, 65(1), e41,1-6.