High-Intensity Interval Training (HIIT) and Chronic Diseases: An Emerging Trend in the Scientific Literature? A Bibliometric Analysis

Abstract

Aim: This study performs a bibliometric analysis to identify scientific trends regarding the effects of high-intensity interval training on individuals with chronic diseases. 
Method: A total of 1 312 English language articles obtained from the Web of Science database and published between 1989 and 2025 were evaluated. Within the scope of the study, only “article”-type publications were included, and language and index (SCIE, SSCI, ESCI) filters were applied. Publications were analyzed using VOSviewer software in terms of distribution by year, country collaborations, keyword clusters, time trends, and citation analysis. 
Results: According to the results of the analysis, a significant increase in publications on HIIT and chronic diseases was observed after 2016. Canada, the UK, Australia, and Iran are among the most productive countries, while the US, despite having a central position on the map of inter-country collaboration, did not make it to the top 10 in the number of publications. 
Conclusion: Keyword clusters revealed that HIIT was intensively studied in relation to metabolic and cardiovascular disorders such as diabetes, obesity, and hypertension. Citation analysis findings show that articles on heart diseases, metabolic syndrome, and insulin resistance are prominent. The findings indicate that HIIT has been adopted not only for athletic performance enhancement but also as an effective intervention tool in the management of chronic diseases. 

Keywords

• High-intensity interval training
• chronic diseases
• physical activity
• bibliometric analysis

Yüksek Yoğunluklu Aralıklı Antrenmanlar ve Kronik Hastalıklar: Bilimsel Literatürde Ortaya Çıkan Bir Eğilim mi? Bibliyometrik Bir Analiz

Abstract

Amaç: Bu çalışma, yüksek yoğunluklu aralıklı antrenmanların kronik hastalıklara sahip bireylerdeki etkilerine yönelik bilimsel eğilimleri belirlemek üzere bibliyometrik bir analiz gerçekleştirmektedir.
Yöntem: Web of Science veri tabanından elde edilen ve 1989–2025 yılları arasında yayımlanan 1,312 İngilizce makale değerlendirmeye alınmıştır. Araştırma kapsamında yalnızca “makale” türündeki yayınlar dahil edilmiş, dil ve indeks (SCIE, SSCI, ESCI) filtreleri uygulanmıştır. Yayınlar VOSviewer yazılımı kullanılarak yıllara göre dağılım, ülke iş birlikleri, anahtar kelime kümelenmeleri, zaman trendleri ve atıf analizleri bakımından incelenmiştir.
Bulgular: Analiz sonuçlarına göre, 2016 sonrası dönemde HIIT ve kronik hastalıklar konusundaki yayınlarda dikkate değer bir artış gözlenmiştir. Kanada, İngiltere, Avustralya ve İran en üretken ülkeler arasında yer alırken, ABD ülkeler arası işbirliği haritasında merkezi bir konuma sahip olmasına rağmen, yayın sayısında ilk 10’a girememiştir. 
Sonuç: Anahtar kelime kümelenmeleri incelendiğinde HIIT’in diyabet, obezite, hipertansiyon gibi metabolik ve kardiyovasküler bozukluklarla ilişkili olarak yoğun biçimde çalışıldığı tespit edilmiştir. Atıf analizi bulguları ise, kalp hastalıkları, metabolik sendrom ve insülin direnci konularındaki makalelerin öne çıktığını göstermektedir. Araştırma sonuçları, HIIT’in yalnızca sportif performans geliştirme amacıyla değil, aynı zamanda kronik hastalıkların yönetiminde etkin bir müdahale aracı olarak benimsendiğini göstermektedir. 

Keywords

• Yüksek yoğunluklu aralıklı antrenman
• Kronik hastalıklar
• Fiziksel aktivite
• Bibliyometrik analiz

References

1. 1. Laursen P, Buchheit M. Science And Application of High-Intensity Interval Training. Human Kinetics; 2019.
2. 2. Cassidy S, Thoma C, Houghton D, Trenell MI. High-intensity interval training: A review of its impact on glucose control and cardiometabolic health. Diabetologia. 2017;60(1):7-23.
3. 3. Nicolò A, Girardi M. The physiology of interval training: A new target to HIIT. The Journal of Physiology. 2016;594(24):7169. doi: 10.1113/JP273466.
4. 4. Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: Exercise effects on brain and cognition. Nature Reviews Neuroscience. 2008;9(1):58-65.
5. 5. Kao SC, Westfall DR, Soneson J, Gurd B, Hillman CH. Comparison of the acute effects of high‐intensity interval training and continuous aerobic walking on inhibitory control. Psychophysiology. 2017;54(9):1335-1345. doi: 10.1111/psyp.12889.
6. 6. Fang B, Kim Y, Choi M. Effect of cycle-based high-intensity interval training and moderate to moderate-intensity continuous training in adolescent soccer players. In Healthcare. 2021;(9)12:1628.
7. 7. Campbell E, Coulter EH, Paul L. High intensity interval training for people with multiple sclerosis: A systematic review. Multiple Sclerosis and Related Disorders. 2018;24:55-63.
8. 8. Lee S, Spector J, Reilly S. High-intensity interval training programme for obese youth (HIP4YOUTH): A pilot feasibility study. Journal of Sports Sciences. 2017;35(18):1794-1798. doi: 10.1080/02640414.2016.1237671.

9. 9. Amundsen BH, Rognmo Ø, Hatlen-Rebhan G, Slørdahl SA. High-intensity aerobic exercise improves diastolic function in coronary artery disease. Scandinavian Cardiovascular Journal. 2008;42(2):110-117. doi: 10.1080/14017430701744477.
10. 10. Motl RW, Fernhall B. Accurate prediction of cardiorespiratory fitness using cycle ergometry in minimally disabled persons with relapsing-remitting multiple sclerosis. Archives of Physical Medicine and Rehabilitation. 2012;93(3):490-495.
11. 11. Şenocak E. Tip-2 diyabetli hastalarda farklı şiddetteki gözetimli egzersiz programlarının egzersiz kapasitesi ve kognitif fonksiyon üzerine etkisi. [yüksek lisans tezi]. İstanbul, Türkiye: Marmara Üniversitesi, Sağlık Bilimleri Enstitüsü, Fizyoterapi ve Rehabilitasyon Anabilim Dalı; 2019.
12. 12. Mugele H, Freitag N, Wilhelmi J, et al. High-intensity interval training in the therapy and aftercare of cancer patients: A systematic review with meta-analysis. Journal of Cancer Survivorship. 2019;13:205-223. doi: 10.1007/s11764-019-00743-3.
13. 13. Sillet A. Definition and use of bibliometrics in research. Soins; La Revue de Reference Infirmiere. 2013;781:29-30.
14. 14. Durieux V, Gevenois PA. Bibliometric indicators: Quality measurements of scientific publication. Radiology. 2010;255(2):342-351. doi: 10.1148/radiol.09090626.
15. 15. Ikpaahindi L. An overview of bibliometrics: Its measurements, laws and their applications. Libri. 1985;35:163.
16. 16. Wisløff U, Støylen A, Loennechen JP, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: A randomized study. Circulation. 2007;115(24):3086-3094.
17. 17. Tjønna AE, Lee SJ, Rognmo Ø, et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: A pilot study. Circulation. 2008;118(4):346-354. doi: 10.1161/CIRCULATIONAHA.108.772822.
18. 18. Little JP, Gillen JB, Percival ME, et al. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. Journal of Applied Physiology. 2011;111(6):1554-1560.
19. 19. Ejaz H, Zeeshan HM, Ahmad F, et al. Bibliometric analysis of publications on the omicron variant from 2020 to 2022 in the Scopus database using R and VOSviewer. International Journal of Environmental Research and Public Health. 2022;19(19):12407.
20. 20. Brück O. A bibliometric analysis of geographic disparities in the authorship of leading medical journals. Communications Medicine. 2023. doi: 10.1038/s43856-023-00418-2.
21. 21. You Y, Li W, Liu J, Li X, Fu Y, Ma X. Bibliometric review to explore emerging high-intensity interval training in health promotion: A new century picture. Frontiers in Public Health. 2021;9:697-633. doi: 10.3389/fpubh.2021.697633.
22. 22. Liu H, Liu F, Ji H, Dai Z, Han W. A bibliometric analysis of high-intensity interval training in cardiac rehabilitation. International Journal of Environmental Research and Public Health. 2022;19(21):13745. doi: 10.3390/ijerph192113745.
23. 23. Liu JX, Zhu L, Li PJ, Li N, Xu YB. Effectiveness of high-intensity interval training on glycemic control and cardiorespiratory fitness in patients with type 2 diabetes: A systematic review and meta-analysis. Aging Clinical and Experimental Research. 2018;31:575-593. doi: 10.1007/s40520-018-1012-z.
24. 24. McGregor G, Powell R, Begg B, et al. High-intensity interval training in cardiac rehabilitation: A multi-centre randomized controlled trial. European Journal of Preventive Cardiology. 2023;30(9):745-755. doi: 10.1093/eurjpc/zwad039.
25. 25. Kristiansen J, Sjúrðarson T, Grove EL, et al. Feasibility and impact of whole-body high-intensity interval training in patients with stable coronary artery disease: A randomised controlled trial. Scientific Reports. 2022;12(1):17295. doi: 10.1038/s41598-022-21655-w.
26. 26. Romero-Vera L, Ulloa-Díaz D, Araya-Sierralta S, et al. Effects of high-intensity interval training on blood pressure levels in hypertensive patients: A systematic review and meta-analysis of randomized clinical trials. Life. 2024;14(12):1661. doi: 10.3390/life14121661.
27. 27. Matos MAD, Vieira DV, Pinhal KC, et al. High-intensity interval training improves markers of oxidative metabolism in skeletal muscle of individuals with obesity and insulin resistance. Frontiers in Physiology. 2018;9:1451. doi: 10.3389/fphys.2018.01451.
28. 28. Jelleyman C, Yates T, O'Donovan G, et al. The effects of high‐intensity interval training on glucose regulation and insulin resistance: A meta‐analysis. Obesity Reviews. 2015;16(11):942-961. doi: 10.1111/obr.12317.
29. 29. Sert H, Gulbahar Eren M, Gurcay B, Koc F. The effectiveness of a high-intensity interval exercise on cardiometabolic health and quality of life in older adults: A systematic review and meta-analysis. BMC Sports Science, Medicine and Rehabilitation. 2025;17(1):1-15.